Navigation Links
Research team recognizes predator-producing bacteria
Date:12/11/2012

Unique viruses called bacteriophages may play an important role in competition among bacterial strains, influencing the overall ecosystem of the human intestine, scientists at The University of Texas at Arlington and UT Southwestern Medical Center say.

A team led by Lora V. Hooper, an associate professor of immunology and microbiology at The University of Texas Southwestern Medical Center, and including UT Arlington assistant professor of biology Jorge Rodrigues examined the bacteriophages, or phages, produced by genetic information harbored in the chromosome of the mammalian gut bacterium Enterococcus faecalis. They found that a phage unique to Enterococcus faecalis strain V583 in mice acts as a predator, infecting and harming other similar, competing bacterial strains. They believe these lab results suggest what goes on in the human intestine.

"This organism is using phage as a way to compete in your gut. If the phage is released and gets rid of all the other microbes, then strain V583 will have more nutrients available," Rodrigues said. "It opens up new questions about the role of phages in the gut system. Ultimately, you could use this as a technique to control bacteria in a natural way."

The findings were presented in October in the Proceedings of the National Academy of Sciences in a paper called, "A composite bacteriophage alters colonization by an intestinal commensal bacterium." It is available online here. Other co-authors were members of Hooper's lab: Breck A. Duerkop, Charmaine V. Clements and Darcy Rollins.

"Now that we've established the role of these bacteriophages, our team is working on trying to discover the specific triggers that lead to phage production in the gut," said Hooper, a Howard Hughes Medical Institute investigator. "We also want to understand whether there are other phages that play a role in shaping the composition of gut bacterial communities."

Bacteria are abundant in the human gastrointestinal tract, and scientists are increasingly trying to understand their role in human health. Of those bacteria, Enterococcus faecalis, also known asE. faecalis, can constitute as much as 0.5 to 0.9 percent of gut microflora, according to the researchers. Outside of the gut, E. faecalis can cause dangerous infections, such as endocarditis, and is often resistant to standard antibiotics like vancomycin.


'/>"/>

Contact: Traci Peterson
tpeterso@uta.edu
817-272-9208
University of Texas at Arlington
Source:Eurekalert

Related medicine news :

1. UAlberta medical researchers make key discovery in fight against Alzheimers disease
2. NIH scientists reflect on gains in emerging infectious disease awareness, research and response
3. 2 UT Southwestern scientists honored as rising stars in Texas research
4. Anti-aging gene identified as tumor suppressor in mice, research finds
5. Moffitt researchers say effective immunotherapy for melanoma hinges on blocking suppressive factors
6. Kinsey research: Postpartum women less stressed by threats unrelated to the baby
7. Family Counseling & Crisis Intervention Services in the US Industry Market Research Report from IBISWorld has Been Updated
8. Wayne State researcher finds possible clue to childrens early antisocial behavior
9. Pharmacy researcher finds most popular weight-loss drug strongly alters other drug therapies
10. Boston College researcher looks to stop a deadly parasite in its tracks
11. Survey shows breakthrough medical research relies heavily on NIH funding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... (PRWEB) , ... February 24, 2017 , ... The International ... 7th annual “Imagine Me Beyond What You See” body image mannequin art competition. Selected ... will be showcased and the winner revealed at the 31st annual iaedp Symposium, March ...
(Date:2/24/2017)... ... February 24, 2017 , ... Congratulations to Head Over ... on February 12th. Ms. Esparza qualified into this prestigious status after winning ... in Las Vegas, Nevada. Frida is one of approximately 25 gymnasts in the ...
(Date:2/23/2017)... CO (PRWEB) , ... February 23, 2017 , ... The ... announce the winner of the 2016 National Education Policy Center Bunkum Award. We invite ... reviewed in 2016. , This year’s Bunkum winner is the Center for American Progress ...
(Date:2/23/2017)... ... February 23, 2017 , ... Los Angeles-based weight loss surgeon Michael Feiz, ... June: From Not to Hot,” which will begin airing on February 24, 2017. The ... millions from the 2012 reality television series, “Here Comes Honey Boo Boo.” The earlier ...
(Date:2/23/2017)... Los Angeles, California (PRWEB) , ... February 23, ... ... for Global Sports Development will host a diverse symposium on “Doping ... School of Law and Sheppard Mullin Richter & Hampton LLP. The symposium will ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Feb. 24, 2017 Research and Markets ... Analysis & Trends - Industry Forecast to 2025" report to ... ... CAGR of around 23.8% over the next decade to reach approximately ... market estimates and forecasts for all the given segments on global ...
(Date:2/24/2017)... Research and Markets has announced the addition of the ... offering. ... Hemophilia Drugs Price Analysis and Strategies - 2016, provides drug pricing data ... following questions: What are the key drugs ... the Global Hemophilia market? What are the unit prices ...
(Date:2/24/2017)... -- In conjunction with DURECT Corporation,s (Nasdaq: DRRX ... are invited to listen to a conference call that ... March 14, 2017 at 4:30 pm Eastern Time (1:30 ... of the presentation will be available by accessing DURECT,s ... If you are unable to participate during the live ...
Breaking Medicine Technology: