Navigation Links
Research team led by Cedars-Sinai identifies genes linked to ulcerative colitis
Date:3/17/2010

LOS ANGELES (March 16, 2010) A study of the human genome led by Cedars-Sinai researchers has now identified genes linked to ulcerative colitis, offering clues as to what causes the condition and potential avenues for new therapies to treat the disease.

The study, published in Nature Genetics, examined genes of nearly 13,000 patients to determine which parts of the genome are linked to ulcerative colitis. The study demonstrated more than 30 regions of the genome are connected to the risk of developing ulcerative colitis.

"This gives us a number of insights into the disease," said Dermot P.B. McGovern, M.D., Ph.D., director of Translational Medicine for the Inflammatory Bowel and Immunobiology Research Institute at Cedars-Sinai Medical Center and primary author of the paper. "An increased understanding of the genetics gives us some insight into what causes ulcerative colitis and will potentially help us indentify new therapies for ulcerative colitis."

Understanding the genetics of the disease may also explain why the condition varies so much from patient to patient in severity, symptoms and response to therapies. In turn, said McGovern, this can lead to a more personalized approach to treating ulcerative colitis patients. For example, in addition to more effectively matching currently available medications to patients, the study may help identify entirely new avenues for research, enabling doctors to develop new treatments for ulcerative colitis.

Ulcerative colitis, one of the most common types of Inflammatory Bowel Disease or IBD, is a chronic digestive disorder. An estimated 1.4 million Americans have IBD, and about 30,000 new cases are diagnosed each year. Ulcerative colitis causes inflammation and ulcers in the top layers of the lining of the large intestine. The most common symptoms include abdominal pain, bloody diarrhea and bleeding from the rectum. Patients may also experience fatigue, weight loss and loss of
'/>"/>

Contact: Nicole White
nicole.white@cshs.org
310-423-5215
Cedars-Sinai Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers ID brain abnormalities in children exposed to methamphetamine in utero
2. New Research from EBRI: Older Workers Trending Toward More Part-Time Work
3. Mount Sinai researchers are the first to identify heart abnormalities in World Trade Center workers
4. Autism Research Study Announced By Children's Health Council
5. Research identifies potential new use for cancer treatment
6. Researchers discover chemical that may protect hearts of muscular dystrophy patients
7. Nuvo Research enrolls first patient in Phase 2 WF10 allergic rhinitis trial
8. Researchers recommend curriculum on unhealthy substance use
9. Using new approach, Mayo Clinic researchers find level of gene alters risk of Alzheimers disease
10. CEMPER.COM Launches New Link Research Tool Version with New Data Source Support for SeoMoz, Sistrix, SEMrush and Majestic SEO
11. Carnegie Mellon research provides insight into brains decision-making process
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... July 24, 2014 The federal ... ) in the U.S. District Court, District ... for plaintiff medical information covered by the federal ... the July 16th Order, U.S. District Judge Douglas ... Fresenius Medical Care the right to receive HIPAA- ...
(Date:7/24/2014)... IL (PRWEB) July 24, 2014 In a ... infertility expert and founder of Lotus Blossom Consulting LLC ... Rosato entitled Three Ways to Cut the High Cost ... way to minimize costs is to maximize your chance of ... advice on choosing a clinic. , “I am always ...
(Date:7/24/2014)... of Association Executives (ASAE) announced its 2014 Power of ... American Society of Anesthesiologists (ASA). , The ASA ... A Gold Award, one of the top honors from ... of the world through education on the global anesthesia ... care. , ASA was also honored with a Power ...
(Date:7/24/2014)... Kathleen Doheny HealthDay Reporter ... children often don,t view their kids as unhealthy or recognize ... a new study. The children of the families surveyed ... the Hasbro Children,s Hospital in Providence, R.I. "A third ... study researcher Dr. Kyung Rhee, now an assistant professor of ...
(Date:7/24/2014)... Pools and beaches are the place to ... dangerous, especially for small children, so Amica Insurance ... to the Centers for Disease Control and Prevention, children between ... for water-related injuries and deaths. It’s important to know the ... Amica is offering the following tips from the American Red ...
Breaking Medicine News(10 mins):Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 4Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 2Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 3Health News:Parents of Obese Kids Often View Them as Healthy 2Health News:Parents of Obese Kids Often View Them as Healthy 3Health News:Keep Kids Safe in the Water with 5 Tips from Amica 2
... , MONDAY, Aug. 29 (HealthDay News) -- Kids who ... preschoolers to grow into adults who lack self-control, a ... there are some individuals who consistently presented as high ... cognitive neuroscientist at the Sackler Institute for Developmental Psychobiology ...
... of improved management at the acute stage, the risk ... decreased by about 50% in the past 10 years. ... hospital, has resulted in improved survival and fewer recurrent ... try and further decrease long-term mortality in patients who ...
... 30, 2011] Vaccinating infants against rotavirus also prevents serious disease ... by the Centers for Disease Control and Prevention (CDC). This ... results of the study are published in The Journal ... . Rotavirus is a major cause of severe diarrhea ...
... HealthDay Reporter , MONDAY, Aug. 29 (HealthDay News) -- ... and Armageddon. Current events have left adults reeling as ... the last with no relent and no apparent end in ... kids who are worriers, they see this stuff is everywhere," ...
... , MONDAY, Aug. 29 (HealthDay News) -- ... be hazardous business, a new study shows. It found ... of being hit at crosswalks, and listening to music is ... environment lab that simulated cars moving in multiple directions, more ...
... multidisciplinary educational programme in cardiovascular prevention directed to ... cardiovascular risk. Cardiovascular prevention could have more success ... in the whole family, "said investigator Luciana Fornari, ... inspiration for this study, presented today at the ...
Cached Medicine News:Health News:'Gimme' Kids Often Grow Into 'Gimme' Adults 2Health News:'Gimme' Kids Often Grow Into 'Gimme' Adults 3Health News:What do patients receiving optimal medical therapy after a heart attack die from? 2Health News:Rotavirus vaccination of infants also protects unvaccinated older children and adults 2Health News:For Kids, Natural Disasters Can Whip Up Worries 2Health News:For Kids, Natural Disasters Can Whip Up Worries 3Health News:Mobile Devices Dangerous for Pedestrians, Too 2Health News:How a cardiovascular prevention program in a Brazilian school reduced parent's CVD risk 2
(Date:7/24/2014)... , July 24, 2014 LSI Medience ... an Agreement with Kineticos, a Raleigh-Durham, ... Kineticos will support LSI Medience in identifying opportunities ... to demonstrate utility in clinical trials. ... utility in diagnosis of sepsis, prognosis of septic ...
(Date:7/24/2014)...  The American Association for Homecare (AAHomecare) yesterday ... help address audit issues in the HME industry ... the information technology lead in shaping its HME ... billing and business management solutions for nearly 3,000 ... support this important initiative on behalf of all ...
(Date:7/24/2014)... 24, 2014 Decision Resources Group finds that, ... countries ( France , Germany ... Spain and the United Kingdom ... first once-daily long-acting beta2 agonist/inhaled corticosteroid (LABA/ICS) fixed-dose combination ... Relvar as a first-line LABA/ICS FDC in the treatment ...
Breaking Medicine Technology:LSI Medience Corporation and Kineticos Sign Agreement Related to the Presepsin Biomarker in Sepsis Management and Treatment 2Brightree Joins AAHomecare as Corporate Partner and IT Lead on HME Audit Key 2Surveyed EU5 Pulmonologists Expect that Relvar, the First Once-Daily LABA/ICS FDC, Will Experience Healthy Uptake in Asthma 2Surveyed EU5 Pulmonologists Expect that Relvar, the First Once-Daily LABA/ICS FDC, Will Experience Healthy Uptake in Asthma 3
... Shire plc (LSE: SHP, NASDAQ: SHPGY ... on the approval status and availability of ProAmatine® (midodrine ... orthostatic hypotension (SOH).  Shire has engaged in consistent dialogue ... the past 12 months in the hopes of either ...
... 22, 2011 PediaVision, maker of the new Spot vision ... upgrading their PediaVision screening units to the new Spot vision ... into the Lions Clubs on-going screening program. Dr. Hauser Weiler, ... the Lions Clubs in 1987.  He has dedicated himself to ...
Cached Medicine Technology:Shire Provides Update on ProAmatine® (midodrine HCl) 2Shire Provides Update on ProAmatine® (midodrine HCl) 3Shire Provides Update on ProAmatine® (midodrine HCl) 4Lions Clubs of Virginia Acquire 8 New Spot Vision Screeners 2Lions Clubs of Virginia Acquire 8 New Spot Vision Screeners 3Lions Clubs of Virginia Acquire 8 New Spot Vision Screeners 4
Sera available in three levels for the control of accuracy and precision for up to 31 analytes...
Human based material available in two levels for the control of accuracy and precision for upto 23 analytes....
CRP Liquid Conrtols level 3...
The GLU method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of glucose in serum, plasma, urine and cerebrospinal fluid....
Medicine Products: