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Research team identifies new mechanism with suspected role in cancer
Date:10/18/2010

a cell has, the more susceptible it is to this problem occurring, Chin said. Overexpression of prolactin receptors in patients has been linked to cancer in the past.

Chin, who has been investigating the molecular basis of cancer for years, said he is encouraged about uncovering this new step. He points to drugs, such as Herceptin, that target receptors to combat cancer.

"This will be extremely important for breast cancer and other cancer therapy by targeting receptors," he said.

One possibility will be developing monoclonal antibodies to target the prolactin receptors directly, he said. But artificial compounds could also be developed to block the receptors from joining as dimers.


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Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert

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