Navigation Links
Research team honored for innovative science to advance cancer research
Date:3/25/2011

ORLANDO, Fla. The Fifth Annual AACR Team Science Award will be given to a team of internationally renowned molecular biologists, epidemiologists, biostatisticians and clinicians from Fred Hutchinson Cancer Research Center and University of Washington who have worked together on human papillomavirus (HPV) for more than 20 years.

This award recognizes an outstanding interdisciplinary research team for its innovative and meritorious science that has advanced or will likely advance cancer research, detection, diagnosis, prevention or treatment.

"This team's work exemplifies how cancer research can dramatically impact public health," said Margaret Foti, Ph.D., M.D. (h.c.), chief executive officer of the AACR. "The researchers' long-term collaborations in basic science, epidemiology and clinical research played a vital role in increasing our understanding of HPV and developing the HPV vaccine, which has the potential to prevent more than half a million HPV-associated cancers each year, worldwide."

By combining molecular assays to detect and characterize HPV infections with epidemiologic approaches, the 12-member team, led by Denise Galloway, Ph.D., head of the Cancer Biology Program at Fred Hutchinson Cancer Research Center, showed that HPVs are associated with nearly all genital-tract cancers and with a significant proportion of head and neck cancers. They conducted what is among the largest case-control studies of HPV-associated cancers and revealed that a variety of exposures notably a high number of sexual partners and early age at first intercourse were common across most of the anogenital cancer sites. The researchers also identified factors beyond sexual activity, such as immunosuppression, that contributed to HPV infection.

The team played a pivotal role in making virus-like particle-based vaccines a reality, from the early basic science work to the epidemiology, to the proof-of-principle clinical trial that showed that a monovalent HPV 16 vaccine protected against HPV 16 infection and disease.

"Our team is thrilled to receive such a wonderful honor," said Galloway. "Credit is due to the entire HPV research community the investigators, research fellows, students and study participants who helped to make our efforts a reality. We are delighted to have been able to contribute to an international team of scientists that collectively moved the field from a state in which the etiology of cervical cancer was not known, to now have vaccines to prevent HPV."

Additionally, Galloway and colleagues developed and tested new strategies for early detection and treatment of HPV-related cancers. Their clinical studies demonstrated the cost-effectiveness of using HPV DNA testing of clinician-collected cervical samples or self-collected vaginal samples in screening programs as well as the potential for using novel biomarkers to more accurately diagnose HPV-related cancers and precancerous lesions.

The AACR Team Science Award, generously supported by a grant from Eli Lilly and Company, is given to affect change within the traditional cancer research culture by recognizing those individuals and institutions that value and foster interdisciplinary team science. The team will collectively receive a $50,000 prize and will be cited for its leadership role in fostering team science. Honorees include (in alphabetical order):

  • Janet Daling, Ph.D., member emeritus, public health sciences division, Fred Hutchinson Cancer Research Center, and professor emeritus, department of epidemiology, University of Washington;

  • Denise Galloway, Ph.D., member, human biology and public health sciences divisions, Fred Hutchinson Cancer Research Center, and research professor, departments of microbiology and pathology, University of Washington;

  • James Hughes, Ph.D., professor, department of biostatistics, University of Washington;

  • Nancy Kiviat, M.D., professor, department of pathology, University of Washington;

  • Laura Koutsky, Ph.D., professor, department of epidemiology, University of Washington;

  • Margaret Madeleine, Ph.D., assistant member, public health sciences division, Fred Hutchinson Cancer Research Center, and assistant professor, department of epidemiology, University of Washington;

  • Constance Mao, M.D., assistant professor, department of obstetrics and gynecology, University of Washington, and director, Harborview Women's Colposcopy Clinic;

  • Barbara McKnight, Ph.D., member, public health sciences division, Fred Hutchinson Cancer Research Center, and professor, department of biostatistics, University of Washington;

  • Peggy Porter, M.D., member, human biology and public health sciences divisions, Fred Hutchinson Cancer Research Center, and professor, department of pathology, University of Washington;

  • Stephen Schwartz, Ph.D., member, public health sciences division, Fred Hutchinson Cancer Research Center, and professor, department of epidemiology, University of Washington;

  • Hisham Tamimi, M.D., professor, department of obstetrics and gynecology, University of Washington; and,

  • Long-fu Xi, Ph.D., research associate professor, department of pathology, University of Washington.

The AACR Team Science Award will be presented at the AACR 102nd Annual Meeting 2011 during the Opening Ceremony on Sunday, April 3 in the Orange County Convention Center, in Orlando, Fla.


'/>"/>

Contact: Michele Sharp
Michele.Sharp@aacr.org
267-646-0622
American Association for Cancer Research
Source:Eurekalert

Related medicine news :

1. Embedded Mobile & M2M Device revenues to Rise to Almost $19 Billion Globally by 2014, Says Juniper Research
2. 2010 HSR Impact Award recognizes surgical safety research
3. MSU launches first anti-counterfeiting research program
4. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
5. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
6. Researchers discover new way to kill pediatric brain tumors
7. Family Research Council: Planned Parenthood Report Oversexualizes Ten-Year-Olds, Undermines Parental Authority
8. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
9. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
10. International Diabetes Federation awards $2 million to 9 global diabetes research projects
11. Gladstones Robert Mahley to receive Research!America advocacy award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... 24, 2016 , ... A recent article published June 14 on ... article goes on to state that individuals are now more comfortable seeking to undergo ... such as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills ...
(Date:6/24/2016)... ... 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out of ... verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... ... is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening ... Talker Award, an essay contest in which patients and their families pay tribute to ... at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this ...
(Date:6/24/2016)... Nevada (PRWEB) , ... June 24, 2016 , ... ... Vegas client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations ... in Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... DUBLIN , June 27, 2016 Jazz ... the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act ... proposed acquisition of Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: ... 11:59 p.m. (Eastern Daylight Time). As previously ... entered into a definitive merger agreement under which Jazz ...
(Date:6/24/2016)... HILL, N.C. , June 24, 2016 /PRNewswire/ ... healthcare decisions and regulators/payers have placed more emphasis ... new environment, patient support programs in the pharmaceutical ... for patients, medications. Consequently, pharmaceutical companies are focusing ... ensure they are providing products and services that ...
(Date:6/24/2016)... , June 24, 2016   Bay Area ... Network,s Dean Center for Tick Borne Illness ... and Rehabilitation, MIT Hacking Medicine, University of California, ... today announced the five finalists of Lyme ... disease.  More than 100 scientists, clinicians, researchers, entrepreneurs, ...
Breaking Medicine Technology: