Navigation Links
Research team documents benefits of endovascular stent repair for traumatic aortic injury
Date:4/30/2010

(SACRAMENTO, Calif.) A UC Davis team of cardiovascular specialists has demonstrated the effectiveness of using stents -- as compared to traditional open-chest surgery -- to repair aortas that are torn as the result of accidents. The researchers will present their findings at the American Association for Thoracic Surgery Aortic Symposium 2010, which takes place April 29-30 in New York City.

"We are always looking for ways to reduce the impact of surgical treatment for patients, especially in instances where there can be multiple and potentially life-threatening injuries," said Royce Calhoun, a cardiothoracic surgeon and principal investigator of the research. "Our results show that it is possible to use stents to repair thoracic aortic tears due to trauma and improve results at the same time."

For the study, the team compared outcomes for 31 patients who received endovascular stent implantation with outcomes for 32 patients who received traditional open-chest surgery between June 2001 and October 2009. Those included in the study had sustained blunt-force injuries to their aortas as a result of wide range of traumas, including car or motorcycle crashes, falls or being crushed by heavy objects.

Stents are slender, small fabric sleeves that maintain their shape by means of an outer mesh. During the procedure, a stent is inserted into a blood vessel through a small incision -- typically in the groin -- then guided to the injury site, where it is triggered to expand against blood vessel walls and patch the injured area. In contrast, the standard surgical method requires long incisions down the length of the chest, sometimes extending into the abdomen. Ribs must be spread or removed, and patients usually must be connected to a heart-lung machine.

In general, stent procedures are associated with fewer complications and reduced recovery time than more-invasive surgical approaches. Patients in the UC Davis study who received stents, as compared to those who received open-chest surgery, were in the operating room for less than half the time and needed significantly fewer blood transfusions. The group who received stents also experienced less kidney failure and had a lower death rate.

While traditional open-chest surgical methods remain appropriate in certain circumstances -- for example, when multiple branches of the aorta are injured in addition to the aorta -- Calhoun said the study shows promise for the endovascular technique becoming the preferred approach for treating aortic tears. Moreover, while stents can be a temporary treatment until a patient's condition allows a more definitive procedure, follow-up care of the study participants has shown no evidence of stent-related problems or issues for those who were still growing physically.

"Patients in the study are doing really well," said Calhoun, who in 2006 helped launch the UC Davis thoracic endovascular aortic repair program, which combines the institution's extensive expertise in vascular medicine, surgery, cardiology and trauma care. "We're very optimistic -- even if stents prove in the long-run to be most appropriate only as a temporary fix for aortic tears -- that this procedure can save lives."

The stents used in the UC Davis study are approved by the U.S. Food and Drug Administration for repairing aneurysms. Their application in trauma repair, however, is currently considered off-label usage. Calhoun and his colleagues are preparing to participate with other select institutions in a large clinical trial evaluating the efficacy of new stent devices designed specifically for repairing thoracic aorta damage. The manufacturer will apply that data to seek broader FDA approval of the devices.


'/>"/>

Contact: Karen Finney
karen.finney@ucdmc.ucdavis.edu
916-734-9064
University of California - Davis - Health System
Source:Eurekalert

Related medicine news :

1. Top Researcher Writes on Autism for Britannica; Baron-Cohen, Others, Report on Causes, Diagnosis and Treatment of Widespread Condition
2. New research about human genetic diseases and human development
3. New Finding Could Mark Shift in Alzheimers Research
4. Researchers attack stem cells that cause colon cancer
5. Canada joins international network providing free access to health research
6. Journal editors call for standards in comparative effectiveness research
7. Outstanding young gastroenterologists receive AGA Foundation 2010 Research Scholars Award
8. Second AGA Foundation/Bernard Lee Schwartz Foundation Research Scholar Award presented
9. LA BioMed awarded research grant to study HIV prevention gel
10. New research reinforces anti-inflammatory properties of tart cherries
11. Are research participants safe enough?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from PsychTests.com reveals ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... San Diego, CA (PRWEB) , ... June 24, 2016 , ... ... up with the American Cancer Society and the Road To Recovery® program to drive ... care to seniors and other adults to ensure the highest quality of life and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... WAYNE, Pa. , June 23, 2016 ... provider, will launch its next generation clinical outcomes platform, Bracket ... DIA Meeting held on June 26 – 30, 2016 in ... 6.0, the first electronic Clinical Outcome Assessment product of its ... DIA Booth #715. Bracket eCOA 6.0 is a ...
(Date:6/23/2016)... 23, 2016 Revolutionary technology includes ... Oticon , industry leaders in advanced audiology and hearing ... Oticon Opn ™, the world,s first internet connected hearing ... IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... number of ,world firsts,: , TwinLink™ - ...
(Date:6/23/2016)... , June 23, 2016  Experian Health, ... and transforming the patient payment and care ... innovative new products and services that will ... revenue cycle offerings. These award-winning solutions will ... workflows, remain compliant in an ever-changing environment ...
Breaking Medicine Technology: