Navigation Links
Research suggests promise of cell therapy for bowel disease
Date:9/19/2012

WINSTON-SALEM, N.C. Sept. 19, 2012 New research shows that a special population of stem cells found in cord blood has the innate ability to migrate to the intestine and contribute to the cell population there, suggesting the cells' potential to treat inflammatory bowel disease (IBD).

"These cells are involved in the formation of blood vessels and may prove to be a tool for improving the vessel abnormalities found in IBD," said lead author Graca Almeida-Porada, M.D., Ph.D., a professor at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine. The research is published in the current print issue of the journal Hepatology.

Up to 1 million Americans have IBD, which is characterized by frequent diarrhea and abdominal pain. IBD actually refers to two conditions ulcerative colitis and Crohn's disease in which the intestines become red and swollen and develop ulcers. With IBD, blood vessels in the intestine leak and contribute to inflammation.

While there is currently no cure for IBD, there are drug therapies aimed at reducing inflammation and preventing the immune response. However, these therapies aren't always effective. The long-term aim of the research is to develop an injectable cell therapy to induce tissue recovery.

The work, performed while Almeida-Porada was at the University of Nevada, also involved colleagues from Indiana University School of Medicine. The researchers studied a special population of cells, known as endothelial colony-forming cells, found in cord blood, bone marrow and circulating blood. The finding in 1997 that the cells can contribute to blood vessel formation in adults, not just embryos, initiated the notion of using them for therapy. Studies in humans have validated the ability of these cells to improve reduced blood flow to the limbs and to treat heart diseases.

However, there have been few studies to explore the inherent biologic ability of these cells to home t
'/>"/>

Contact: Karen Richardson
krchrdsn@wakehealth.edu
336-716-4453
Wake Forest Baptist Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. UCLA Brain Injury Research Center gets NCAA funding for research on sports concussions
2. NIH awards $20 million over 5 years to train next generation of global health researchers
3. Researchers develop a new cell and animal model of inflammatory breast cancer
4. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
5. Sexually abused boys at risk for more unsafe sex: UBC research
6. Researchers Find Gene Mutations That May Be a Key to Autism
7. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
8. Researchers find evidence of banned antibiotics in poultry products
9. Presidential keynote address and new research highlights from the American Society of Pediatric Otolaryngology meeting
10. Scientific session and new research highlights
11. NJ stroke researchers report advances in spatial neglect research at AAN Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... one out of three survivors of critical illness, ... The Lancet Respiratory Medicine , and the majority ... mentally. , It is one of the largest ... outcomes of critical care survivors, according to lead ... and it highlights a significant public health issue, ...
(Date:4/24/2014)... National Science Foundation has awarded LSU Health Sciences ... (REU) Site grant in the amount of $295,635. ... from diverse social and educational backgrounds, underrepresented in ... The project will provide students with training ... It will be led by Principal Investigator ...
(Date:4/23/2014)... from Sub-Saharan Africa, Latin America and Caribbean islands ... new research from St. Michael,s Hospital. , The ... of Obstetrics and Gynaecology , assessed the differences ... native-born women in six high-immigration countries Australia ... Valencia) and the United States (California, New Jersey ...
(Date:4/23/2014)... 2014 The American Society for Radiation Oncology (ASTRO) ... Postoperative Radiation Therapy for Endometrial Cancer: An ASTRO ... radiation therapy in the treatment of endometrial cancer. ... May-June 2014 issue of Practical Radiation Oncology ... ASTRO. The full-length guideline is available as an ...
(Date:4/23/2014)... The internal surface area of the gastro-intestinal tract has ... square meters. Scientists at the Sahlgrenska Academy have used ... , "Actually, the inner surface of the gastro-intestinal tract ... says scientist Lars Fndriks. , The digestive tract, which ... through the intestines, has a length of about 5 ...
Breaking Medicine News(10 mins):Health News:Vanderbilt study finds physical signs of depression common among ICU survivors 2Health News:Vanderbilt study finds physical signs of depression common among ICU survivors 3Health News:Pregnancy complications may be more common in immigrants from certain regions 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 3Health News:The surface area of the digestive tract 'only' as large as a studio apartment 2
... ... Mr. Ohad Goren will function as Pollogen,s CEO. Pollogen recently launched its latest technology- ... action - fat reduction. , ... Tel-Aviv, Israel (PRWEB) April 19, 2010 -- Pollogen Ltd , a ...
... ... accumulated medical records knowledge to offer a full Electronic Medical Records (EMR) data conversion ... ... in healthcare connectivity solutions, now offers a full range of EMR to EMR Data ...
... those who get something lodged in their throat die , ... young children who choke after swallowing a foreign object is ... real, the latest research indicates. , "In such cases, the ... K. Shah, a pediatric otolaryngologist with the Children,s National Medical ...
... first study of vitamin K and Non-Hodgkin lymphoma ... found that people who have higher intakes of vitamin K ... lymphoma. Non-Hodgkin Lymphoma is a cancer of the immune ... United States. At the 101st Annual Meeting ...
... SAN MARCOS, TXStudents, perceptions of their overall experience on ... accomplishments, but research has also found a solid relationship ... perceptions of quality of life. Are campus green spaces ... undergrads? A new study investigating this question revealed some ...
... screening, diagnosis , MONDAY, April 19 (HealthDay News) -- Researchers ... tests could be a sign that patients are at higher ... that in blacks, a common germ boosts the risk of ... often become cancerous. , Both studies are slated to be ...
Cached Medicine News:Health News:Pollogen Ltd. Names Ohad Goren Chief Executive Officer 2Health News:Pollogen Ltd. Names Ohad Goren Chief Executive Officer 3Health News:ELLKAY Launches Electronic Medical Records (EMR) Conversion Division to Healthcare Industry 2Health News:ELLKAY Launches Electronic Medical Records (EMR) Conversion Division to Healthcare Industry 3Health News:Fatal Choking a Real Risk Among Toddlers 2Health News:Fatal Choking a Real Risk Among Toddlers 3Health News:Vitamin K may protect against developing non-Hodgkin's lymphoma, say Mayo Clinic researchers 2Health News:Vitamin K may protect against developing non-Hodgkin's lymphoma, say Mayo Clinic researchers 3Health News:Campus green space more important for undergrads 2Health News:New Risk Factors for Colon Cancer Studied 2
(Date:1/15/2014)... January 15, 2014 BreedIT Corp (OTC: ... worldwide distributor of highly sophisticated agro-breeding solutions for plant ... 2014, the Company,s board of directors appointed chemistry and ... its new member of the board. From ...
(Date:1/15/2014)... 2014  In an unprecedented effort to curb the spread of "superbugs" ... transport vehicles, an advanced and portable UV germicidal lamp manufactured by ... time. In order to prevent EMS paramedics and ... West Palm Beach Fire Rescue is the first ...
(Date:1/15/2014)... MultiCell Technologies, Inc. (OTC Bulletin Board: MCET.OB ... composition of matter, biological targets, mechanism of action, methods ... This patent application describes a novel class ... which interfere with the basic homeostatic cellular processes in ...
Breaking Medicine Technology:BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3Superbugs No Longer Ride In Rescue Vehicles 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 3
... announced that 12-month outcomes data from a subset analysis ... of print in the Journal of Interventional Cardiology ... company,s Genous Stent in diabetic patients, with low definite ... The study investigated the 1,236 diabetic patients from ...
... 23, 2011 NephRx Corporation today announced issuance ... peptide NX002, which currently is in preclinical development ... reported that NX002 had demonstrated significant efficacy when ...  Mucositis is a debilitating and often dose-limiting condition ...
Cached Medicine Technology:Data Published in the Journal of Interventional Cardiology Demonstrate Effectiveness and Safety of OrbusNeich's Genous™ Stent in Diabetic Patients 2Data Published in the Journal of Interventional Cardiology Demonstrate Effectiveness and Safety of OrbusNeich's Genous™ Stent in Diabetic Patients 3NephRx Corp. Awarded New U.S. Patent for Oral Mucositis Agent NX002 2NephRx Corp. Awarded New U.S. Patent for Oral Mucositis Agent NX002 3
Image Diagnostics' Aspect100U is specifically designed for ease of use and high quality image outcome during urological procedures. Aspect tables benefit from a trim, lightweight design, ensuring a s...
The design of this table top is based on advanced functionality for specific urological requirements. This composite product sets a new standard for urological imaging....
... A revolutionary urological imaging ... benefits that translate into improved ... x 1k imaging technology physicians ... to see more anatomical detail ...
Drew Scientific has been making leading edge and top quality CBC systems for over 15 years.,The Excell 16/18 offers a reliable alternative for a 3 part differential....
Medicine Products: