Navigation Links
Research shows rapid adoption of newer, more expensive prostate cancer treatments

Boston, MA With 180,000 men diagnosed with prostate cancer each year, it is one of the most common types of cancer in the country. For this reason, it has been cited as a good marker for health care spending in general, reflective of the greater trends across the United States. New research from the Dana-Farber/Brigham and Women's Cancer Center (DF/BWCC) shows that newer, more expensive treatment options for prostate cancer were adopted rapidly and widely during 2002 2005 without proof of their cost-effectiveness, and may offer explanations for why health care spending accounts for 17 percent of the nation's GDP. This research is published online March 14 and will appear in an upcoming print edition of the Journal of Clinical Oncology.

"In an era of limited resources, it is important for us as a society to take stock of how we're spending our money", said Paul Nguyen, MD, lead author of the study and a radiation oncologist at the Dana-Farber/Brigham and Women's Cancer Center. "We don't think these patterns are unique to prostate cancer, but used it as an example and found that in the United States, newer and more expensive technologies were rapidly adopted before we knew if they were worth the added cost, or in the case of robotic surgery, whether they provide benefits over standard treatment."

Researchers evaluated the use and cost of surgical and radiation treatments for prostate cancer using Medicare linked data from more than 45,000 men who were 65 years or older between 2002 and 2005. The data accounted for patients who received two types of surgical treatments: the older treatment, open radical prostatectomy and the newer treatment, robot-assisted or laparoscopic prostatectomy; and two types of radiation treatments: the older type, three-dimensional conformal radiation therapy (3D-CRT) and the newer option, intensity-modulated radiation therapy (IMRT).

Researchers report that among surgical patients, the number who received robot-assisted or laparoscopic prostatectomy increased substantially from 1.5 percent of diagnoses in 2002 to 28.7 percent of diagnoses in 2005. Among patients who received radiation therapy, researchers observed the same trend towards rapid adoption of IMRT, the newer treatment option. In 2002, 28.7 percent of men diagnosed received IMRT compared to 81.7 percent in 2005. Additionally, among men who received brachytherapy, supplemental IMRT increased from 8.5 percent in 2002 to 31.1 percent in 2005. Patients receiving the newer type of therapy tended to live in higher-income and metropolitan regions, and were more likely to have earlier stage disease and be of Asian descent.

Researchers also report that Medicare spending on the newer treatment options was significantly higher than on traditional treatments, with the difference between IMRT and 3D-CRT being nearly $11,000 per patient and the difference between robot-assisted prostatectomy and open radical prostatectomy being $293, although the authors suggest that this is an underestimate of the underlying cost differences in the surgeries since it does not account for the cost of purchasing and maintaining the robot. After extrapolating these numbers to the total U.S. population, researchers report an additional of spending adding up to nearly $350 million in 2005 on newer treatment options when compared to the traditional and less costly alternative therapy for men diagnosed with prostate cancer.

"Our paper should not be interpreted as being "anti-technology", and we do not want to stand in the way of bringing newer and better treatments to market. On the other hand, health care spending is a zero-sum game, and a greater emphasis on comparative effectiveness research is needed so we can better separate the wheat from the chaff. While IMRT has proven itself to significantly reduce the rate of serious rectal bleeding after prostate radiation, the study to show it is cost-effective was not published until 2006, when over 80% of the country was already using it. In the case of robotic surgery, there are still uncertainties over what benefits it has over the open procedure," Nguyen said.


Contact: Lori J. Shanks
Brigham and Women's Hospital

Related medicine news :

1. Embedded Mobile & M2M Device revenues to Rise to Almost $19 Billion Globally by 2014, Says Juniper Research
2. 2010 HSR Impact Award recognizes surgical safety research
3. MSU launches first anti-counterfeiting research program
4. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
5. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
6. Researchers discover new way to kill pediatric brain tumors
7. Family Research Council: Planned Parenthood Report Oversexualizes Ten-Year-Olds, Undermines Parental Authority
8. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
9. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
10. International Diabetes Federation awards $2 million to 9 global diabetes research projects
11. Gladstones Robert Mahley to receive Research!America advocacy award
Post Your Comments:
(Date:11/24/2015)... N.Y. (PRWEB) , ... November 24, 2015 , ... Autism ... Tuesday, the global movement driven by social media and the generosity of people around ... then encourage their social media networks to give – and share the personal stories ...
(Date:11/24/2015)... ... 2015 , ... All her life, Don Peck’s mother wondered if she was a descendant of ... been. After a 25-year search for information, Don and his aunt discovered that she ... name. Turns out, it was Don’s father who was descended from not one, but ...
(Date:11/24/2015)... ... , ... Dehydration, defined as a loss of body water content, can make ... and heat stroke and death will quickly follow. A normal human body is 70 ... system and structure requires water to function properly. Kleyne, who believes that medical research ...
(Date:11/24/2015)... , ... November 24, 2015 , ... ... , the only authorized OSHA Training Institute Education Center in Northern California, is ... the holiday season’s major sales events. As the volume of sales and ...
(Date:11/24/2015)... ... November 24, 2015 , ... Add a fresh touch to this ... and affordable way to bring long-lasting style and cheer to any space. , Holiday ... the air and keep on giving all year long. , “Holiday plants make a ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Nov. 24, 2015  Ascendant Solutions, Inc. (Pink Sheets: ... Board of Directors has declared a special 1 percent stock ... is payable December 14, 2015, to shareholders of record December ... of additional shares of common stock. ... is a strong endorsement of our confidence in Ascendant,s growth ...
(Date:11/24/2015)... st  Scientific Assembly and Annual Meeting of ... taking place in Chicago on Nov-29 th ... --> st  Scientific Assembly and Annual Meeting of the Radiological ... in Chicago on Nov-29 th through ... Molecular Dynamics will present its revolutionary whole body CZT digital SPECT/CT ...
(Date:11/24/2015)... November 24, 2015 --> ... Inhibitors, MTTP Inhibitors, ApoB Inhibitors and PPAR Agonists ... to grow at the fastest rates? This visiongain ... data, trends, opportunities and prospects there. ,  ,Our 199-page ... most lucrative areas in the industry and the future ...
Breaking Medicine Technology: