Navigation Links
Research says TB infection may be underestimated among people taking corticosteroid pills
Date:6/25/2014

TORONTO, June 26, 2014Tuberculosis infection among people taking corticosteroid pills may be underestimated, new research suggests. Current guidelines for what constitutes a positive TB skin test among corticosteroid pill users may not be capturing all those who are infected, said

Dr. Nicholas Vozoris, a respirologist in the Tuberculosis Program at St. Michael's Hospital.

Previous research has shown that people who take corticosteroid pills, such as Prednisone, and have inhaled the TB bacteria, have an eight times higher risk of the bacteria becoming active than people who are not taking the drugs.

Dr. Vozoris said that would suggest they should be screened more often for TB infection.

However, an examination of more than 7,300 people in the U.S. National Health and Nutrition Examination Survey found this was not the case. The survey, a series of studies designed to assess the health and nutritional status of adults and children in the United States, is unique in that it combines interviews and physical examinations.

The findings were published today in the European Respiratory Journal.

He found that although taking corticosteroid pills was a risk factor for turning latent TB into active TB, those patients were screened less often for TB than others. They were also less likely to be prescribed TB-fighting drugs prophylactically.

Dr. Vozoris said that for the general population, producing a bump at least 10 millimetres in diameter following a TB skin test likely means that one has inhaled the TB bacteria. Current guidelines recommend that the bump be only five millimetres long if the patient is taking corticosteroid pills, but Dr. Vozoris said there is no evidence to support that is the correct cut-off. The study results show that 3.5-mm might be a more appropriate cut-off.

Corticosteroid pills are commonly prescribed for people with asthma, chronic obstructive pulmonary disease, inflammatory bowel disease, inflammatory arthritis and cancer. They work by decreasing inflammation, but they also suppress the immune system.

The Respirology Division of St. Michael's Hospital has a Tuberculosis Program dedicated exclusively to caring for patients with TB disease and infection. The program's clinic has 1,900 patient visits a year, making it one of the largest TB clinics in Canada.


'/>"/>

Contact: Leslie Shepherd
shepherdl@smh.ca
416-864-6094
St. Michael's Hospital
Source:Eurekalert  

Related medicine news :

1. Researchers call for patients who receive home nutritional care to have emergency plans
2. Chronic brain damage not as prevalent in NFL players, say researchers
3. St. Jude Childrens Research Hospital names James R. Downing, M.D., CEO
4. Researchers treat incarceration as a disease epidemic, discover small changes help
5. New research shows link unlikely between insomnia symptoms and high blood pressure
6. Researchers publish one of the longest longitudinal studies of cognition in MS
7. UF part of research team that finds equine influenza virus in camels
8. Endocrine Society honors Sen. Dick Durbin with Biomedical Research Champion Award
9. Picture books for visually impaired kids go 3-D thanks to CU-Boulder research team
10. SLU researchers see possible answer to chemo pain in a multiple sclerosis drug
11. Beaumont research finds advanced CT scanners reduce patient radiation exposure
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Research says TB infection may be underestimated among people taking corticosteroid pills
(Date:2/23/2017)... , ... February 23, 2017 , ... The 89th Academy ... winner of the 2016 National Education Policy Center Bunkum Award. We invite you to ... 2016. , This year’s Bunkum winner is the Center for American Progress (CAP), for ...
(Date:2/23/2017)... ... February 23, 2017 , ... Rare Disease Report®, which is ... in Rare Disease Day events, hosted by the Rare Disease Legislative Advocates (RDLA) ... website, weekly e-newsletter and quarterly publication, will be conducting interviews with patients and ...
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... Los Angeles-based ... episodes of WE TV’s “Mama June: From Not to Hot,” which will begin airing ... “Mama” June Shannon, known to millions from the 2012 reality television series, “Here Comes ...
(Date:2/23/2017)... NJ (PRWEB) , ... February 23, 2017 , ... ... in thought leadership , media relations, content marketing, social media management, corporate ... several clients already in the state and in nearby New Hampshire, Massachusetts and ...
(Date:2/23/2017)... ... February 23, 2017 , ... On April 13, 2017, ... on “Doping in Sport: How the Culture Might Change,” in conjunction ... The symposium will be held at Pepperdine University in Malibu, California. , Sir ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Feb. 23, 2017  Directors from Pharma To Market Pty ... have joined forces, resulting in the founding of Pharma To Market ... Pharma To Market are pleased to announce their expansion into ... Singapore . The company are delighted to appoint ... of the Singapore based entity. Joelle brings ...
(Date:2/24/2017)... Feb 24, 2017 Medivir AB ... for a new Board of Directors that will be ... Nomination Committee comprises representatives of the company,s three largest ... 2016 who have accepted a seat on the Nomination ... of the 2016-2017 Nomination Committee was as follows:  ...
(Date:2/23/2017)... Research and Markets has announced the addition ... - 2016" report to their offering. ... The latest research Autism Spectrum Disorder ... and benchmarks in the global Autism Spectrum Disorder market. The ... are the key drugs marketed for Autism Spectrum Disorder and their ...
Breaking Medicine Technology: