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Research results show new way for cholesterol treatment
Date:2/5/2014

bad cholesterol. This opens the way for a completely new strategy for treating increased cholesterol," says postdoc Camilla Gustafsen from Aarhus University, who also participated in the survey.

Possible alternative to statins

The positive effect of inhibiting sortilin has been demonstrated in mice and studies in humans suggest that the same correlation is present here. The next step is now larger studies on humans. The hope is that the discovery can be used to develop medicine that can act as an alternative to statins, which are the most widely used cholesterol-reducing medication. Particularly because not everyone can either tolerate or benefit from statins.

"All eyes have been on PCSK9 for ten years. Now we present a new discovery, which contributes to the understanding of PCSK9 and can, at the same time, pave the way for a treatment that apparently has the same effect as PCSK9 inhibitors. The PCSK9 market is already limited by patents and copyrights, so this can make it possible for new pharmaceutical companies to enter the scene for the benefit of the patients," emphasises Simon Glerup.


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Contact: Simon Glerup
sg@biokemi.au.dk
45-51-22-17-27
Aarhus University
Source:Eurekalert

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