Navigation Links
Research program focuses on genetic mutations and cancer risk
Date:5/5/2008

PITTSBURGH, May 5 The University of Pittsburgh Cancer Institute (UPCI) today announced the establishment of the Frieda G. and Saul F. Shapira BRCA Cancer Research Program. BRCA 1 and 2 are two genes that, when mutated, dramatically increase the risk of breast, prostate, ovarian and pancreatic cancers.

I am excited about the addition of this research program to UPCI, said Ronald Herberman, M.D., director of UPCI and the University of Pittsburgh Medical Center (UPMC) Cancer Centers. The more we learn about these mutations, the better chance we have to target high-risk patients and to find innovative ways to reduce their cancer risk.

Women who possess either mutation have a 50 to 80 percent lifetime risk of developing breast cancer, and the disease progresses more quickly than in individuals without the mutations. Experts estimate that as many as one out of every 345 people in the U.S. carries a BRCA mutation, but for individuals of Ashkenazi (Eastern European) Jewish descent, the number is approximately one in 40.

These mutations have been linked primarily with an increased risk of breast cancer in women, but they also increase the risk for other cancers. Both men and women can carry the genetic mutations, which means they can be passed to children from either parent.

The David S. and Karen A. Shapira Foundation committed an initial $1 million for the program, structuring the gift as a matching grant to raise an additional $1.5 million from individuals and foundations. UPMC is matching these gifts on a dollar-for-dollar basis, for an overall goal of $5 million.

Currently, the burden of cancer costs each American approximately $936 a year, said Dr. Herberman. The National Cancer Institutes budget supporting research amounts to only $21 per American annually. To fund promising cancer research, researchers need other means of support. A gift like the one we have received from the Shapira Foundation, complemented by funds from the community and UPMC, will go a long way to supporting this important program.


'/>"/>

Contact: Courtney McCrimmon
McCrimmonCP@upmc.edu
412-647-3555
University of Pittsburgh Medical Center
Source:Eurekalert

Related medicine news :

1. ESA contributes to ocean carbon cycle research
2. CNS Response, Inc: rEEG(R) Research to be Presented at 38th National Council Conference
3. Stanford researchers synthesize compound to flush HIV out of hiding
4. World first: researchers develop completely automated anesthesia system
5. St. Davids HealthCare and Texas Cardiac Arrhythmia Announce International Center For Training, Research and Treatment of Heart Rhythm Disorders
6. Rutgers research partner Stemcyte, Inc., expands to New Jersey
7. Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology Meeting
8. New research on hearing health underscores the importance of better hearing and speech month
9. Family history places women at risk of pelvic organ prolapse, SLU research finds
10. Researchers Develop Quick Way to Create Human Antibodies
11. New Research From Packard Childrens Hospital Experts Presented at 2008 Pediatric Academic Societies Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... California (PRWEB) , ... June 25, 2016 , ... "With ... fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... customizable and all within Final Cut Pro X . Simply select a ProHand ...
(Date:6/25/2016)... ... 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland ... iHire in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness ... & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle Cell ... pain and the benefits of holistic treatments, Serenity Recovery Center of Marne, ... Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red blood ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all ... brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented its ... Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor the outstanding ... Medicine Practice and Pediatric Emergency Medicine Practice. , “With this award, we ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 2016 Jazz Pharmaceuticals plc (Nasdaq: ... Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended ("HSR"), ... Inc. ("Celator"; Nasdaq: CPXX ) expired effective ... As previously announced on May 31, 2016, ... agreement under which Jazz Pharmaceuticals has commenced a tender ...
(Date:6/24/2016)... 24, 2016  Consumers have taken a more ... placed more emphasis on patient outcomes. ... in the pharmaceutical industry have evolved beyond just ... companies are focusing on becoming more patient-oriented across ... and services that improve health. ...
(Date:6/24/2016)... , June 24, 2016   Bay Area ... Network,s Dean Center for Tick Borne Illness ... and Rehabilitation, MIT Hacking Medicine, University of California, ... today announced the five finalists of Lyme ... disease.  More than 100 scientists, clinicians, researchers, entrepreneurs, ...
Breaking Medicine Technology: