Navigation Links
Research presented at ISHLT shows promise of addressing critical organ shortage and
Date:4/10/2008

Boston, MA April 10, 2008 Data from experimental work on the use of organs from cardiac arrested donors will be presented this week at the International Society for Heart and Lung Transplantations 28th Annual Meeting and Scientific Sessions. Utilizing donors after cardiac death (DCD), also known as non-heart-beating donors (NHBDs) has the potential to overcome a critical shortage of suitable donor organs for lung, and possibly heart, transplantation.

In addition, strategies for organ preservation during transport from donor to recipient will be a primary topic of discussion at the ISHLT meeting running through Saturday at the Boston Marriott Copley Place and Hynes Convention Center.

There is a worldwide shortage of quality donor organs for transplantation. This year, we are going to hear about clinical updates on non-heart-beating lung donors, and also exciting new experimental work on the possible use of hearts from cardiac-arrested donors, said Steven Tsui, M.D., F.R.C.S., Director of Transplantation and Surgeon, Papworth Hospital, U.K. In addition, there has been a lot of interest in techniques aiming to maintain, and possibly improve, donor organ function once they have been removed from the donor.

NON-HEART-BEATING DONORS

Organ transplantation is currently limited by a shortage of suitable donors, which results in longer waiting times for patients and a substantial risk of dying before transplantation.

Promising research results suggest the potential to immediately increase the number of lungs available for transplantation. Although thousands of patients are on lung transplant waiting lists around the world, only a small percentage actually receive transplants. And likewise, a small proportion of individuals identified as organ donors actually have suitable lungs for transplantation.

During the ISHLT mini-oral session I: The Non-Heart Beating Donor for Heart Transplantation, Ayyaz Ali, F.R.C.S., Transplant Fellow from Papworth, will provide a report regarding the potential for resuscitating donor hearts from NHBDs using extracorporeal perfusion, which in turn could mean a larger portion of donor hearts being used to transplant patients who need them (Abstract #143).

RE-CONDITIONING DONOR ORGANS

Donor organs tend to deteriorate with time after brain-stem death. They may suffer further injury during transport to the recipient hospital. From time-to-time, their function declines so much that they can no longer be transplanted safely. It may be possible to maintain donor organs in a more healthy state during transport or even improve their function to make transplantation safer.

Recently introduced concepts such as various Ex-Vivo Lung Perfusion (EVLP) techniques will be discussed during the Meeting. Likewise, clinical experience of the innovative Organ Care System (OCS) for donor hearts will be reported, said Dr. Tsui.

The cold preservation method, which has been in practice for more than 25 years, delivers the organ in a non-functioning state immersed in a cold solution for preservation during transport. The time during transport in this method is referred to as cold ischemic time, more specifically the interval beginning when an organ is removed from the donor and is cooled with the solution, to the time when the organ is implanted.

Conversely, the Organ Care System (OCS) is based on warm blood perfusion technology, which it uses to maintain organs in a warm, functioning state. With OCS, the warm state mimics the environment of the human body during transport from organ donor to recipient. Nutrient rich, oxygenated blood is continuously pumped through the heart in order to maintain the organ in a living, beating state. Preserving an organ with this method reduces cold ischemic time and allows for evaluation of organ function during transport.


'/>"/>

Contact: Lauren Mason
lmason@masonpr.com
210-857-2521
International Society for Heart and Lung Transplantation
Source:Eurekalert

Related medicine news :

1. DeBakey Awards to Recognize Excellence in Biomedical Research Journalism
2. Deafness Research Foundation 50th Anniversary Celebration
3. Researchers pilot new electronic system for infectious illness
4. Researchers Find Gene Mutation That Increases Asthma Risk
5. How fast youll age is written in the bones, TAU research finds
6. Boston College biologists build a better mouse model for cancer research
7. Massachusetts Affiliate of Susan G. Komen for the Cure to Spotlight Gaps in Breast Cancer Research
8. Researchers Define Mechanism of Methamphetamine Addiction
9. New research shows neuroprotective effect of lovastatin
10. Attacks against medical researchers: Time to take a stand
11. New research for mechanical support devices in pediatrics to be released at ISHLT
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... ... March 28, 2017 , ... For many women, getting birth control isn’t as easy as it ... either don’t have access to a health care facility or a pharmacy within 60 minutes ... the United States or for many who are faced with health or personal issues that ...
(Date:3/28/2017)... SEATTLE, Washington and CARTERSVILLE, Georgia (PRWEB) , ... ... ... adding another senior analyst to its award-winning team. Ruel Williamson brings his extensive ... Advisors, which has been a leader in the real estate valuation industry for ...
(Date:3/28/2017)... ... March 28, 2017 , ... Revolution for Truth has ... to protect parental rights and civil liberties, and to restore transparency within government ... demonstration coincides with a press conference taking place Friday morning calling on President ...
(Date:3/28/2017)... ... , ... Dr. Isabella Wentz, PharmD, FASCP, one of the leading thyroid experts ... Secret. Dr. Wentz talked about journey and research recently on a blog and discussed ... the only solution to deal with thyroid disease. , Dr. Wentz completed her ...
(Date:3/28/2017)... ... March 28, 2017 , ... Medforce Technologies, Inc., a leading ... it has joined the National Association for Home Care and Hospice (NAHC), the ... and dying Americans of all ages and the caregiver who provide them with ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... Summary GBI ... a Key Component of Multichannel Marketing" provides a ... in the digital age. While the pharmaceutical ... advancements, it has been much slower to adopt ... traditional channels and methods. However, the decreasing effectiveness ...
(Date:3/28/2017)... 2017  Orexigen Therapeutics, Inc. (Nasdaq: OREX ... fourth quarter and year ended December 31, 2016. ... progress for Orexigen, beginning with the re-acquisition of the ... March, the team at Orexigen demonstrated remarkable focus, executing ... and strengthened our Company while rewarding us full control ...
(Date:3/28/2017)... and TORONTO , March 28, 2017 ... leading full service medical device development firm, announced today ... Toronto -based medical device industrial design ... serve medtech companies throughout North America ... experienced medical device talent spanning the design, engineering, regulatory, ...
Breaking Medicine Technology: