Navigation Links
Research presented at ISHLT shows promise of addressing critical organ shortage and
Date:4/10/2008

Boston, MA April 10, 2008 Data from experimental work on the use of organs from cardiac arrested donors will be presented this week at the International Society for Heart and Lung Transplantations 28th Annual Meeting and Scientific Sessions. Utilizing donors after cardiac death (DCD), also known as non-heart-beating donors (NHBDs) has the potential to overcome a critical shortage of suitable donor organs for lung, and possibly heart, transplantation.

In addition, strategies for organ preservation during transport from donor to recipient will be a primary topic of discussion at the ISHLT meeting running through Saturday at the Boston Marriott Copley Place and Hynes Convention Center.

There is a worldwide shortage of quality donor organs for transplantation. This year, we are going to hear about clinical updates on non-heart-beating lung donors, and also exciting new experimental work on the possible use of hearts from cardiac-arrested donors, said Steven Tsui, M.D., F.R.C.S., Director of Transplantation and Surgeon, Papworth Hospital, U.K. In addition, there has been a lot of interest in techniques aiming to maintain, and possibly improve, donor organ function once they have been removed from the donor.

NON-HEART-BEATING DONORS

Organ transplantation is currently limited by a shortage of suitable donors, which results in longer waiting times for patients and a substantial risk of dying before transplantation.

Promising research results suggest the potential to immediately increase the number of lungs available for transplantation. Although thousands of patients are on lung transplant waiting lists around the world, only a small percentage actually receive transplants. And likewise, a small proportion of individuals identified as organ donors actually have suitable lungs for transplantation.

During the ISHLT mini-oral session I: The Non-Heart Beating Donor for Heart Transplantation, Ayyaz Ali, F.R.C.S., Transplant Fellow from Papworth, will provide a report regarding the potential for resuscitating donor hearts from NHBDs using extracorporeal perfusion, which in turn could mean a larger portion of donor hearts being used to transplant patients who need them (Abstract #143).

RE-CONDITIONING DONOR ORGANS

Donor organs tend to deteriorate with time after brain-stem death. They may suffer further injury during transport to the recipient hospital. From time-to-time, their function declines so much that they can no longer be transplanted safely. It may be possible to maintain donor organs in a more healthy state during transport or even improve their function to make transplantation safer.

Recently introduced concepts such as various Ex-Vivo Lung Perfusion (EVLP) techniques will be discussed during the Meeting. Likewise, clinical experience of the innovative Organ Care System (OCS) for donor hearts will be reported, said Dr. Tsui.

The cold preservation method, which has been in practice for more than 25 years, delivers the organ in a non-functioning state immersed in a cold solution for preservation during transport. The time during transport in this method is referred to as cold ischemic time, more specifically the interval beginning when an organ is removed from the donor and is cooled with the solution, to the time when the organ is implanted.

Conversely, the Organ Care System (OCS) is based on warm blood perfusion technology, which it uses to maintain organs in a warm, functioning state. With OCS, the warm state mimics the environment of the human body during transport from organ donor to recipient. Nutrient rich, oxygenated blood is continuously pumped through the heart in order to maintain the organ in a living, beating state. Preserving an organ with this method reduces cold ischemic time and allows for evaluation of organ function during transport.


'/>"/>

Contact: Lauren Mason
lmason@masonpr.com
210-857-2521
International Society for Heart and Lung Transplantation
Source:Eurekalert

Related medicine news :

1. DeBakey Awards to Recognize Excellence in Biomedical Research Journalism
2. Deafness Research Foundation 50th Anniversary Celebration
3. Researchers pilot new electronic system for infectious illness
4. Researchers Find Gene Mutation That Increases Asthma Risk
5. How fast youll age is written in the bones, TAU research finds
6. Boston College biologists build a better mouse model for cancer research
7. Massachusetts Affiliate of Susan G. Komen for the Cure to Spotlight Gaps in Breast Cancer Research
8. Researchers Define Mechanism of Methamphetamine Addiction
9. New research shows neuroprotective effect of lovastatin
10. Attacks against medical researchers: Time to take a stand
11. New research for mechanical support devices in pediatrics to be released at ISHLT
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... ambulance transport experience for the millions of people who require these medical transport ... taxi industry through the use of technology. Now, SmartEMS has put forth an ...
(Date:6/26/2016)... ... 26, 2016 , ... PawPaws brand pet supplements owned by Whole ... enhance the health of felines. The formula is all-natural and is made from Chinese ... PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and ...
(Date:6/25/2016)... ... 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to ... a new, often overlooked aspect of head lice: the parasite’s ability to live away from ... common occurrence, but a necessary one in the event that lice have simply gotten out ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and ... their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took ... the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...  Collagen Matrix, Inc., ("Collagen Matrix") the driving ... collagen and mineral based medical devices for tissue ... Messer has joined the company as Vice ... growing portfolio of oral surgery, neurosurgery, orthopaedic and ... the Collagen Matrix executive team as an accomplished ...
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... Research and Markets has announced the addition of ... report to their offering. ... The World Market for Companion Diagnostics covers the world market ... the report includes the following: , World ... Region (N. America, EU, ROW), 2015-2020 , World IVD ...
Breaking Medicine Technology: