Navigation Links
Research opens up new horizons to the design of customized medicines against breast cancer
Date:5/5/2009

This release is available in Spanish.

A research work carried out at the University of Granada (Spain), in collaboration with the Hospital Complex of Jan (Services of Medical Oncology, Radiology and Pathological Anatomy), has opened up new horizons to the design of customized medicines against breast cancer, from the genetic study of cancer cells. The scientists have also concluded that the study of the gene expression profile involves a promising strategy to individualize and improve tumour treatment, reducing toxicity and increasing its efficiency.

This research work has been carried out by Laura Vera Ramrez in the department of Legal Medicine, Toxicology and Psychiatry, and supervised by Professors Jos Antonio Lorente Acosta, Jos Luis Quiles Morales and Pedro Snchez Rovira. In order to carry out this work, the researchers worked with 90 patients with breast cancer who were being diagnosed and treated in the Hospital Complex of Jan.

This way, through the analysis of patients' genes, the UGR researchers have studied the changes that chemotherapy provokes in patients at a genetic level. The clinical interest of this work is that "allows us to study the response molecular mechanisms to medicines and to design from them other pharmacological medicines according to the genetic features of the patient".

Attacking weak points

According to the experts, the study of such mechanisms "offers information about the weak points of the cells affected by cancer and allows us to attack them directly". At present, almost half of the patients of breast cancer "are over-treated with chemotherapy", and in the opinion of the authors of this work "it is necessary to identify possible therapeutic goals will permit patients to show a better response to alternative treatments".

Besides a genetic approach of patients, the scientists of the UGR have carried out a biochemical approach, studying patients' oxidative stress before and after being subjected to chemotherapy. "Finally they explain-, we have carried out a nutritional and anthropometrical study of the patients to observe the influence of chemotherapy on nutrition".


'/>"/>

Contact: Laura Vera Ramrez
verala79@yahoo.es
34-638-007-535
University of Granada
Source:Eurekalert

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2017)... , ... January 15, 2017 , ... The Gravity Vault ... in Radnor, Pennsylvania. As construction wraps up on the 14,000+ square foot climbing gym, ... Vaults sixth location, including three in New Jersey and two in New York. With ...
(Date:1/14/2017)... ... January 13, 2017 , ... According to ... magnesium-rich Mediterranean diet may lower the risk of type 2 diabetes, Alzheimer’s, and ... many health and wellness benefits linked to a Mediterranean diet are only some ...
(Date:1/13/2017)... California (PRWEB) , ... January 13, 2017 , ... ... carbohydrates that raise blood sugar levels. Counting carbohydrates is as easy as checking ... the only nutrient that affects blood sugar levels. Despite being sugar-free, proteins can ...
(Date:1/13/2017)... ... ... KOAMTAC ®, Inc., a leading manufacturer of Bluetooth barcode scanners and mobile ... collector at the National Retail Federation’s Big Show (NRF17) held January 15-17 in New ... need for more compact and rugged devices for collecting barcode data paired with a ...
(Date:1/13/2017)... , ... January 13, 2017 , ... An inventor from ... black or brown belt in order to diversify my outfits, so he decided to ... wear. , THE T.O.O.B. enhances the appearance of a belt to allow for quick, ...
Breaking Medicine News(10 mins):
(Date:1/13/2017)... 2017 Constant research ongoing in the ... contribute to the demand for western blotting technique. The global  ... US$ 551.0 Mn by 2016 end. Developing economies in ... markets for western blotting, whereas North America ... ...
(Date:1/13/2017)... 13, 2017  Alfalfa, cattle, leafy greens and rosy cheeked ... film , which emphasizes the food industry,s shift from response ... COPAN,s Swab Rinse Kit (SRK™) ... sampling process in the wake of the new FDA ... COPAN is expanding the U.S. production of the ...
(Date:1/13/2017)... -- This morning, Stock-Callers.com draws attention to ... at yesterday,s closing bell: Clovis Oncology Inc. (NASDAQ: ... GALE ), and ACADIA Pharmaceuticals Inc. (NASDAQ: ... to develop technologies and products that combat debilitating and ... use less and cleaner energy, and provide safer, cleaner ...
Breaking Medicine Technology: