Navigation Links
Research opens up new horizons to the design of customized medicines against breast cancer

This release is available in Spanish.

A research work carried out at the University of Granada (Spain), in collaboration with the Hospital Complex of Jan (Services of Medical Oncology, Radiology and Pathological Anatomy), has opened up new horizons to the design of customized medicines against breast cancer, from the genetic study of cancer cells. The scientists have also concluded that the study of the gene expression profile involves a promising strategy to individualize and improve tumour treatment, reducing toxicity and increasing its efficiency.

This research work has been carried out by Laura Vera Ramrez in the department of Legal Medicine, Toxicology and Psychiatry, and supervised by Professors Jos Antonio Lorente Acosta, Jos Luis Quiles Morales and Pedro Snchez Rovira. In order to carry out this work, the researchers worked with 90 patients with breast cancer who were being diagnosed and treated in the Hospital Complex of Jan.

This way, through the analysis of patients' genes, the UGR researchers have studied the changes that chemotherapy provokes in patients at a genetic level. The clinical interest of this work is that "allows us to study the response molecular mechanisms to medicines and to design from them other pharmacological medicines according to the genetic features of the patient".

Attacking weak points

According to the experts, the study of such mechanisms "offers information about the weak points of the cells affected by cancer and allows us to attack them directly". At present, almost half of the patients of breast cancer "are over-treated with chemotherapy", and in the opinion of the authors of this work "it is necessary to identify possible therapeutic goals will permit patients to show a better response to alternative treatments".

Besides a genetic approach of patients, the scientists of the UGR have carried out a biochemical approach, studying patients' oxidative stress before and after being subjected to chemotherapy. "Finally they explain-, we have carried out a nutritional and anthropometrical study of the patients to observe the influence of chemotherapy on nutrition".


Contact: Laura Vera Ramrez
University of Granada

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
(Date:11/30/2015)... (PRWEB) , ... November 30, 2015 , ... ... healthcare professionals worldwide today released the results of a survey of educational needs ... and Africa found a growing global demand for high quality online and face-to-face ...
(Date:11/30/2015)... , ... November 30, 2015 ... ... to announce their strategic partnership at the Radiological Society of North America ... Winscribe, global providers of cutting-edge dictation and speech-enabled documentation software, announced their ...
(Date:11/30/2015)... ... November 30, 2015 , ... Several significant ... coding changes are likely to include new codes for spine and hip X-rays, ... understand the effects of code changes in musculoskeletal, radiology and nervous system sections ...
(Date:11/30/2015)... TX (PRWEB) , ... November 30, 2015 , ... Bayco Products, Inc today announced the ... $11.95 each. Available in a choice of three different colors; red ( NSP-1632 ), yellow ... each run up to 18 hours in constant-on mode, or 27 hours in blinking strobe ...
(Date:11/29/2015)... ... November 30, 2015 , ... Gift ideas ... Sublime Beauty NATURALS®. All products are available on Amazon or its webstore. , ... facial serums and USDA Certified Organic Sesame Oil for Oil Pulling," says Kathy ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... , Nov. 30, 2015   Nuance Communications, Inc. ... National Decision Support Company (NDSC) today jointly announced ... collaboration capabilities that utilize the American College of Radiology,s ... provider organizations to comply with current and emerging ... --> By combining clinical decision support, ...
(Date:11/30/2015)... 2015  Hanger, Inc. (NYSE: HGR ) (the ... terms of its previously announced consent solicitation (as amended ... aggregate principal amount 7⅛% Senior Notes due 2018 (the ... fees payable pursuant to the Consent Solicitation, (ii) the ... the expiration date of the Consent Solicitation.    ...
(Date:11/30/2015)... LONDON and BOSTON , ... to research and develop potential new medicines directed at ... multiple therapeutic areas. --> PFE ) to ... to 10 G protein-coupled receptor (GPCR) targets across multiple ... clinical-stage GPCR structure-guided drug discovery and development company and ...
Breaking Medicine Technology: