Navigation Links
Research opens up new horizons to the design of customized medicines against breast cancer
Date:5/5/2009

This release is available in Spanish.

A research work carried out at the University of Granada (Spain), in collaboration with the Hospital Complex of Jan (Services of Medical Oncology, Radiology and Pathological Anatomy), has opened up new horizons to the design of customized medicines against breast cancer, from the genetic study of cancer cells. The scientists have also concluded that the study of the gene expression profile involves a promising strategy to individualize and improve tumour treatment, reducing toxicity and increasing its efficiency.

This research work has been carried out by Laura Vera Ramrez in the department of Legal Medicine, Toxicology and Psychiatry, and supervised by Professors Jos Antonio Lorente Acosta, Jos Luis Quiles Morales and Pedro Snchez Rovira. In order to carry out this work, the researchers worked with 90 patients with breast cancer who were being diagnosed and treated in the Hospital Complex of Jan.

This way, through the analysis of patients' genes, the UGR researchers have studied the changes that chemotherapy provokes in patients at a genetic level. The clinical interest of this work is that "allows us to study the response molecular mechanisms to medicines and to design from them other pharmacological medicines according to the genetic features of the patient".

Attacking weak points

According to the experts, the study of such mechanisms "offers information about the weak points of the cells affected by cancer and allows us to attack them directly". At present, almost half of the patients of breast cancer "are over-treated with chemotherapy", and in the opinion of the authors of this work "it is necessary to identify possible therapeutic goals will permit patients to show a better response to alternative treatments".

Besides a genetic approach of patients, the scientists of the UGR have carried out a biochemical approach, studying patients' oxidative stress before and after being subjected to chemotherapy. "Finally they explain-, we have carried out a nutritional and anthropometrical study of the patients to observe the influence of chemotherapy on nutrition".


'/>"/>

Contact: Laura Vera Ramrez
verala79@yahoo.es
34-638-007-535
University of Granada
Source:Eurekalert

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2017)... , ... February 23, 2017 , ... The 89th Academy ... winner of the 2016 National Education Policy Center Bunkum Award. We invite you to ... 2016. , This year’s Bunkum winner is the Center for American Progress (CAP), for ...
(Date:2/23/2017)... , ... February 23, 2017 , ... ... with a clinician-based audience, will be participating in Rare Disease Day events, hosted ... D.C. In addition, Rare Disease Report, a website, weekly e-newsletter and quarterly publication, ...
(Date:2/23/2017)... ... ... Los Angeles-based weight loss surgeon Michael Feiz, M.D., F.AC.S. will be appearing ... which will begin airing on February 24, 2017. The show chronicles the weight loss ... television series, “Here Comes Honey Boo Boo.” The earlier series from TLC lasted for ...
(Date:2/23/2017)... , ... February 23, 2017 , ... ... thought leadership , media relations, content marketing, social media management, corporate communications, SEO ... already in the state and in nearby New Hampshire, Massachusetts and Canada, Rosica ...
(Date:2/23/2017)... ... 23, 2017 , ... On April 13, 2017, The ... “Doping in Sport: How the Culture Might Change,” in conjunction with Pepperdine ... will be held at Pepperdine University in Malibu, California. , Sir Philip Craven, ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Feb. 23, 2017 ... insights on the various drugs being developed ... covers all the drugs that are in ... Clinical). The pipeline focuses on novel pharmacologic ... antibodies, stem cell therapies, recombinant proteins and ...
(Date:2/24/2017)... , Feb. 24, 2017  Xynomic Pharmaceuticals, Inc., ... announced that it has acquired exclusive worldwide rights ... best-in-class innovative HDAC inhibitor targeting hematological and solid ... 14 Phase 1 and 2 clinical trials of ... have already been completed, demonstrating that ...
(Date:2/23/2017)... Research and Markets has announced the addition of the ... report to their offering. ... The latest research Autism Spectrum Disorder Drugs Price ... in the global Autism Spectrum Disorder market. The research answers ... key drugs marketed for Autism Spectrum Disorder and their clinical attributes? ...
Breaking Medicine Technology: