Navigation Links
Research opens up new horizons to the design of customized medicines against breast cancer
Date:5/5/2009

This release is available in Spanish.

A research work carried out at the University of Granada (Spain), in collaboration with the Hospital Complex of Jan (Services of Medical Oncology, Radiology and Pathological Anatomy), has opened up new horizons to the design of customized medicines against breast cancer, from the genetic study of cancer cells. The scientists have also concluded that the study of the gene expression profile involves a promising strategy to individualize and improve tumour treatment, reducing toxicity and increasing its efficiency.

This research work has been carried out by Laura Vera Ramrez in the department of Legal Medicine, Toxicology and Psychiatry, and supervised by Professors Jos Antonio Lorente Acosta, Jos Luis Quiles Morales and Pedro Snchez Rovira. In order to carry out this work, the researchers worked with 90 patients with breast cancer who were being diagnosed and treated in the Hospital Complex of Jan.

This way, through the analysis of patients' genes, the UGR researchers have studied the changes that chemotherapy provokes in patients at a genetic level. The clinical interest of this work is that "allows us to study the response molecular mechanisms to medicines and to design from them other pharmacological medicines according to the genetic features of the patient".

Attacking weak points

According to the experts, the study of such mechanisms "offers information about the weak points of the cells affected by cancer and allows us to attack them directly". At present, almost half of the patients of breast cancer "are over-treated with chemotherapy", and in the opinion of the authors of this work "it is necessary to identify possible therapeutic goals will permit patients to show a better response to alternative treatments".

Besides a genetic approach of patients, the scientists of the UGR have carried out a biochemical approach, studying patients' oxidative stress before and after being subjected to chemotherapy. "Finally they explain-, we have carried out a nutritional and anthropometrical study of the patients to observe the influence of chemotherapy on nutrition".


'/>"/>

Contact: Laura Vera Ramrez
verala79@yahoo.es
34-638-007-535
University of Granada
Source:Eurekalert

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... ... March 22, 2017 , ... ... leading digital and print media enterprise focused on cancer patients, cancer centers and ... released a special 12-part educational video series, “No Ifs, Ands, or Butts,” that ...
(Date:3/22/2017)... ... 22, 2017 , ... The Rett Syndrome Research Trust (RSRT) ... that afflicts 350,000 individuals worldwide. Rett Syndrome is caused by alterations in ... females. Following a normal infancy, Rett Syndrome takes effect in toddlerhood depriving ...
(Date:3/22/2017)... , ... March 22, 2017 , ... ... to its Department of Orthopedic Surgery, Division of Hand, Upper Extremity and Microvascular ... surgery. She is board-certified in both Orthopedics and Hand Surgery. , ...
(Date:3/22/2017)... ... March 22, 2017 , ... Intrinsic Imaging, ... therapeutic experience and operational excellence in oncology clinical trials, proudly announces today that ... treatment of non-small cell lung cancer and small cell lung cancer. , Throughout ...
(Date:3/22/2017)... Norwich, NY (PRWEB) , ... March 22, 2017 , ... ... to communities in the greater Nassau County region, is embarking on a combined charity ... breast cancer. , For the last 25 years, the Great Neck Breast Cancer ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... March 22, 2017 AMRI , a ... been working with the life sciences industry to improve ... 25 years, has been recognized for its excellence as ... as part of the Life Science Leader,s 2017 ... expertise, quality and reliability. "Competing with ...
(Date:3/22/2017)... STOCKHOLM , March 22, 2017 ... biopharmaceutical company developing novel anticancer therapies targeting the ... with Memorial Sloan Kettering Cancer Center to study ... p53 by APR-246. The goal of ... efficacy of APR-246 in combination with multiple other ...
(Date:3/22/2017)... Research and Markets has announced the addition of the "Global ... ... market to grow at a CAGR of 14.58% during the period ... been prepared based on an in-depth market analysis with inputs from ... prospects over the coming years. The report also includes a discussion ...
Breaking Medicine Technology: