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Research on the effects of stem cell source and patient age on transplantation outcomes
Date:12/7/2008

(SAN FRANCISCO, December 7, 2008) Two studies examining the effects of stem cell source and patient age on stem cell transplantation outcomes will be explored at a press conference taking place on Sunday, December 7, at 8:00 a.m., during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA. Preliminary results from a study examining a specialized technique for increasing the presence of stem cells in cord blood for transplantation will also be shared during the press conference.

"For years, stem cell transplants have been a standard treatment option for many blood cancers and other hematologic conditions," said Armand Keating, MD, moderator of the press conference and Director, Division of Hematology, and Professor of Medicine at the University of Toronto, Ontario, Canada. "The results of these studies add to the growing body of knowledge about the best regimens available to help produce durable responses and prolonged survival in many groups of patients."

Blood cancers leukemia, lymphoma, and myeloma are typically treated with a combination of treatments including chemotherapy, biological therapy, radiation therapy, and stem cell transplantation. Stem cell transplantation is the process by which blood stem cells are collected from a donor, or from the patient prior to chemotherapy, and then infused into the patient after treatment. The transplanted stem cells travel to the bone marrow and begin to produce new blood cells, replacing those that are destroyed as a side effect of chemotherapy. Stem cell transplants are categorized by the source of the stem cells (bone marrow, peripheral blood, or cord blood) and by their origin autologous (from the patient) or allogeneic (from a donor).

Effect of Stem Cell Source on Transplant Outcomes in Adults With Acute Leukemia: A Comparison of Unrelated Bone Marrow, Peripheral Blood, and Cord Blood [Abstract #151]
Mary Eapen, MBBS, the Cent
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Contact: Laura Stark
lstark@hematology.org
415-978-3505
American Society of Hematology
Source:Eurekalert

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