Navigation Links
Research identifies potential new use for cancer treatment
Date:3/15/2010

Drugs increasingly used to treat cancer could have a major impact on a wide range of infectious diseases, according to new research.

Anti-angiogenic drugs are used to try and prevent cancers from stimulating the growth of the blood vessels they need to survive and grow.

New research by the Centre for Immunology and Infection at the University of York suggests the same drugs may help in the treatment of other diseases including visceral leishmaniasis which kills 70,000 people worldwide every year.

The findings, published online today by the Journal of Clinical Investigation, show that anti-angiogenic drugs can improve the structure of tissues where immune responses are generated and which are often destroyed by chronic infection or inflammation.

The resulting improvement in the immune response can increase the effectiveness of conventional treatments for leishmaniasis, allowing doctors to use lower doses of existing drugs that otherwise have harmful side effects.

Professor Paul Kaye, Director of the Centre for Immunology and Infection, said: "While our research has focused on leishmaniasis the findings could have implications for a range of globally important diseases.

"It is particularly exciting that this potential has been discovered in a class of drugs that are already well-established in clinical practice.

"Our research also identifies ways that anti-angiogenic drugs might be used more effectively in the treatment of cancers."

The research was funded by the Medical Research Council and the Wellcome Trust.

These findings have led to further research, supported by Yorkshire Cancer Research, into the potential use of anti-angiogenic drugs as a "preconditioning agent" in the treatment of melanoma.


'/>"/>

Contact: James Reed
jr576@york.ac.uk
44-190-443-2029
University of York
Source:Eurekalert

Page: 1

Related medicine news :

1. Researchers discover chemical that may protect hearts of muscular dystrophy patients
2. Nuvo Research enrolls first patient in Phase 2 WF10 allergic rhinitis trial
3. Researchers recommend curriculum on unhealthy substance use
4. Using new approach, Mayo Clinic researchers find level of gene alters risk of Alzheimers disease
5. CEMPER.COM Launches New Link Research Tool Version with New Data Source Support for SeoMoz, Sistrix, SEMrush and Majestic SEO
6. Carnegie Mellon research provides insight into brains decision-making process
7. Researchers discover brain tumors grow-or-go switch
8. Get up, get out and go: NC State research tackles childhood obesity
9. A new beat in heart research
10. Harvard School of Public Health unveils comprehensive, public online library of firearms research
11. Penn researcher, Louis J. Soslowsky, PhD, winner of the AAOS Kappa Delta Ann Doner Vaughan Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... Village, CA (PRWEB) , ... April 29, 2016 ... ... Philadelphia Pet Expo to promote their animal line of probiotics, Petbiotics ™, ... see the large turnout of animal rescue groups networking for their non-profit organizations. ...
(Date:4/29/2016)... Wilmington, DE (PRWEB) , ... April 29, 2016 ... ... annual SMG Finance, which will be held May 16th to 18th at the ... all of the SMG managed facilities to collaborate on best practices in public ...
(Date:4/29/2016)... , ... April 29, 2016 , ... In its efforts ... Caregiver Services continues its successful franchise development and expansion as it welcomes Ferdie Vasquez ... managerial and administrative experience in his 32 years of working in various industries. ...
(Date:4/28/2016)... CITY (PRWEB) , ... April 28, 2016 , ... ... is on the world stage this week. A group of researchers and leaders ... on the Progress of Regenerative Medicine and Its Cultural Impact ” and receive ...
(Date:4/28/2016)... (PRWEB) , ... April 28, 2016 , ... University of ... McDonald to the role of vice president of Student Engagement. In addition to ... facilities, athletics and student life areas. , “In the space of just one ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... SHAWNEE, Kan. , April 27, 2016 /PRNewswire/ ... Martabano , a senior from the University of ... winner of the Bayer Excellence in Communication Award ... veterinary schools, which were awarded a total of ... Over the last four years, Bayer has provided ...
(Date:4/27/2016)... 2016 Global  urinalysis market ... by 2022, according to a new report by ... http://photos.prnewswire.com/prnh/20150105/723757 ) , Automation ... and accuracy delivered by the new generation urinalysis ... urinalysis instruments and consumables. For instance, the automatic ...
(Date:4/26/2016)... April 26, 2016 Hill-Rom Holdings, Inc. (NYSE: ... presentation at the Deutsche Bank 41 st Annual Health ... EDT. You are invited to listen to the ... or access it directly at http://edge.media-server.com/m/p/mr4uxgas . A recorded ... conclusion of the live event and accessible at the links ...
Breaking Medicine Technology: