Navigation Links
Research hope for bladder cancer
Date:7/31/2013

Bladder cancer is a common condition an estimated 10,000 people are diagnosed with the disease each year in the UK. It is the seventh most common cancer in the UK, affecting men more than women.

Some people develop invasive bladder cancer, which is where the cancer has grown through the muscle layer of the bladder. When this occurs, there is a higher risk that the cancer will spread to other areas of the body and it is much more difficult to treat.

Until now the signalling process that allows a benign, small polyp to develop into something that spreads and is invasive has not been clear. But research carried out by a team at Plymouth University has for the first identified an important mechanism behind this process.

The research is published today 1st August 2013 in the American Journal of Physiology Renal Physiology.

Key to the research is a protein, pancreatic secretory trypsin inhibitor (PSTI), which is present in most bladder cancers. The research has identified the role PSTI plays in the signalling process that allows the spread and invasion of bladder cancer.

By understanding the process by which this protein helps the cells to spread, and invade into other tissue, researchers can start to develop ways to interrupt this process, potentially leading to new treatments.. This has the potential to improve the survival and life quality of those with early diagnosed bladder cancer, and reduce the instances where rigorous drug regimes or invasive surgery are required.

The research was led by Professor Raymond Playford and Dr. Tanya Marchbank from Plymouth University. Professor Playford said: "Although bladder cancer can be readily treated if caught early enough, once it starts to invade into deeper tissues and spread to distant sites it is a much more difficult, painful and life-affecting cancer to live with. Treatment becomes more difficult as tumours grow deeper into the bladder wall and spread, and survival rates decline it is estimated that just 25 per cent of those with severe invasive bladder cancer will be alive and well three years after diagnosis and treatment. By identifying the mechanism by which bladder cancer develops and spreads, we hope that in time therapies that manipulate this mechanism may be developed to improve the quality of life and survival rates of those with invasive bladder cancer."


'/>"/>

Contact: Andrew Gould
andrew.gould@plymouth.ac.uk
University of Plymouth
Source:Eurekalert

Related medicine news :

1. China Animal Vaccine Market Worth 15.9 Billion By 2016 in New Research Report at RnRMarketResearch.com
2. $1.8 million grant to support research on impact of social stress
3. BMJ editorial: Indias research participant protection policy
4. Eighth Annual Bladder Cancer Think Tank Set to Move Research Forward to Improve Treatment Landscape
5. Survey by Dissertation-Texas Reveals Exceptional Rise in Research Projects
6. U.S. Label Market Worth $19 Billion in 2017 Research Reports Now Available at ReportsnReports.com
7. Nanobiotechnology Market - New Industry Research Report is Now Available for Pre-Order at Transparency Market Research
8. New grant empowers young researchers to find a cure for pancreatic cancer
9. HealthCarePoint and ViS Research Streamline Sharing of Qualifications by Medical Researchers
10. Global Markets for Rapid Medical Diagnostic Kits (Mdks) to Surpass $24.2 Billion by 2017: BCC Research
11. Poland Health Insurance Market Analysis and 2015 Forecasts in New Research Report at RnRMarketResearch.com
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... a leader in post-acute health care, have expanded their existing home health joint ... Health. , AccentCare has been operating a joint venture home health company with ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned and Grand Rapids-based ... and Brightest in Wellness® by Best and Brightest. OnSite Wellness will be honored ... 20 from 7:30 a.m. to 2 p.m. at the Henry Autograph Collection Hotel, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Vohra ... care advancements to physician colleagues, skilled nursing facility medical directors and other clinicians ... Waters of Wound Care." , "At many of these conferences we get to ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... Oct. 10, 2017  NDS received FDA 510(k) clearance in May ... battery-powered display stand specifically designed for endoscopy environments. An innovative secondary ... a clinical solution to support the improvement of patient outcomes, procedural ... ... ...
(Date:10/5/2017)... , Oct. 5, 2017  In response ... of Oral and Maxillofacial Surgeons (AAOMS) released prescribing ... – to be used as a first-line therapy ... Recognizing the ... AAOMS White Paper "Opioid Prescribing: Acute and Postoperative ...
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
Breaking Medicine Technology: