Navigation Links
Research hope for bladder cancer
Date:7/31/2013

Bladder cancer is a common condition an estimated 10,000 people are diagnosed with the disease each year in the UK. It is the seventh most common cancer in the UK, affecting men more than women.

Some people develop invasive bladder cancer, which is where the cancer has grown through the muscle layer of the bladder. When this occurs, there is a higher risk that the cancer will spread to other areas of the body and it is much more difficult to treat.

Until now the signalling process that allows a benign, small polyp to develop into something that spreads and is invasive has not been clear. But research carried out by a team at Plymouth University has for the first identified an important mechanism behind this process.

The research is published today 1st August 2013 in the American Journal of Physiology Renal Physiology.

Key to the research is a protein, pancreatic secretory trypsin inhibitor (PSTI), which is present in most bladder cancers. The research has identified the role PSTI plays in the signalling process that allows the spread and invasion of bladder cancer.

By understanding the process by which this protein helps the cells to spread, and invade into other tissue, researchers can start to develop ways to interrupt this process, potentially leading to new treatments.. This has the potential to improve the survival and life quality of those with early diagnosed bladder cancer, and reduce the instances where rigorous drug regimes or invasive surgery are required.

The research was led by Professor Raymond Playford and Dr. Tanya Marchbank from Plymouth University. Professor Playford said: "Although bladder cancer can be readily treated if caught early enough, once it starts to invade into deeper tissues and spread to distant sites it is a much more difficult, painful and life-affecting cancer to live with. Treatment becomes more difficult as tumours grow deeper into the bladder wall and spread, and survival rates decline it is estimated that just 25 per cent of those with severe invasive bladder cancer will be alive and well three years after diagnosis and treatment. By identifying the mechanism by which bladder cancer develops and spreads, we hope that in time therapies that manipulate this mechanism may be developed to improve the quality of life and survival rates of those with invasive bladder cancer."


'/>"/>

Contact: Andrew Gould
andrew.gould@plymouth.ac.uk
University of Plymouth
Source:Eurekalert

Related medicine news :

1. China Animal Vaccine Market Worth 15.9 Billion By 2016 in New Research Report at RnRMarketResearch.com
2. $1.8 million grant to support research on impact of social stress
3. BMJ editorial: Indias research participant protection policy
4. Eighth Annual Bladder Cancer Think Tank Set to Move Research Forward to Improve Treatment Landscape
5. Survey by Dissertation-Texas Reveals Exceptional Rise in Research Projects
6. U.S. Label Market Worth $19 Billion in 2017 Research Reports Now Available at ReportsnReports.com
7. Nanobiotechnology Market - New Industry Research Report is Now Available for Pre-Order at Transparency Market Research
8. New grant empowers young researchers to find a cure for pancreatic cancer
9. HealthCarePoint and ViS Research Streamline Sharing of Qualifications by Medical Researchers
10. Global Markets for Rapid Medical Diagnostic Kits (Mdks) to Surpass $24.2 Billion by 2017: BCC Research
11. Poland Health Insurance Market Analysis and 2015 Forecasts in New Research Report at RnRMarketResearch.com
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... ... May 04, 2016 , ... Qualitative research, which is ... a deeper understanding of the program, policy or intervention being studied. Both quantitative ... important questions. , In a new brief released today, Reading Qualitative Educational Policy ...
(Date:5/4/2016)... AZ (PRWEB) , ... May 04, 2016 , ... ... Annual Technology & Business Conference. The conference opened on Tuesday with Frank Luntz, ... discussion on NCPDP’s PDMP Solution provided a deep dive on NCPDP’s model solution ...
(Date:5/4/2016)... MA (PRWEB) , ... May 04, 2016 , ... ... help fund Dr. Todd Rider's research and development of DRACO broad-spectrum antiviral therapeutics. ... In the campaign that starts on May 3, 2016 at http://igg.me/at/EndTheVirus ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... (WOCN) Society™ and Canadian Association for Enterostomal Therapy (CAET) will be utilizing ... and planning tools to attendees and exhibitors for the 2016 WOCN Society & ...
(Date:5/4/2016)... ... ... May kicked off with Melanoma Monday , a multi-agency effort to raise ... encouraging her patients, as well as residents all around Dallas, Cleburne, Irving, and Plano, ... in the future. , The dermatology-specific awareness month ends with “Don’t Fry Day,” established ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... 4, 2016 Research ... "Global Acute Ischemic Stroke Market and Competitive ... offering.       (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ... Ischemic Stroke Market and Competitive Landscape Highlights ... Stroke pipeline products, Acute Ischemic Stroke epidemiology, ...
(Date:5/4/2016)... DUBLIN , May 4, 2016 /PRNewswire/ ... the addition of the  "Global Actinic Keratosis ...  report to their offering.       ... Actinic Keratosis Market and Competitive Landscape Highlights ... pipeline products, Actinic Keratosis epidemiology, Actinic Keratosis ...
(Date:5/3/2016)... , May 4, 2016 ... 154 pages, profiling 09 key companies and supported ... professional and in-depth study on the current state ... overview of the industry including definitions, classifications, applications ... analysis is provided for the international market including ...
Breaking Medicine Technology: