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Research highlights need to address hemophilia in developing world
Date:11/16/2009

ward our goal of treatment for all."

In the first study, the researchers found that prevalence of hemophilia A in high-income countries was approximately 12.8 per 100,000 males. The prevalence in lower-income countries was approximately 6.6 per 100,000 males. "The medical community tells us that the incidence of hemophilia A or the number of people born with the condition is the same around the world," Stonebraker explains, "so the difference in prevalence or the number of people living with the condition at any given moment appears to be due to much higher mortality in developing countries."

The study also showed that prevalence of hemophilia has increased over the past 30 years, as treatments for the disorder have improved. In other words, better treatment is helping those with hemophilia A live longer. For example, the United Kingdom had a prevalence of 9.3 per 100,000 in 1974, but it had risen to 21.6 per 100,000 by 2006.

In a second study, Stonebraker and his colleagues found that decreased mortality related to hemophilia A is tied to a willingness by government health-care agencies or private insurers to pay for treatment. Correspondingly, the consumption of factor VIII drugs has increased significantly in developed countries and that trend appears poised to continue, with high-income countries expected to consume more and more factor VIII drugs in the future.

Stonebraker says the two studies should be incredibly helpful as budget-planning tools for insurance companies and those countries that provide national health care, as well as for pharmaceutical companies that will want to project the amount of factor VIII drugs they will need to make to meet market demand. But, Stonebraker says, "the studies also show how much more needs to be done to address hemophilia in the developing world."


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Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University
Source:Eurekalert

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