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Research from the 2012 Genitourinary Cancers Symposium highlights new treatments, compares existing therapies for prostate cancer
Date:1/31/2012

4) Novel Investigational Drug Targeting Bone Metastases Improves Survival for Metastatic Prostate Cancer: A randomized, phase III trial shows that a new radiation-emitting agent aimed at treating bone metastases both improved survival and delayed cancer-related bone problems in men with castration-resistant prostate cancer (CRPC). The agent, radium-223 chloride, is the first alpha particle emitting agent targeting bone metastases shown to improve survival in metastatic CRPC.

5) Study Shows New Targeted Drug Improves Overall Survival in Metastatic Prostate Cancer: An international, randomized phase III trial shows for the first time that an investigational oral drug that halts androgen signaling significantly improves overall survival in patients with metastatic castration-resistant prostate cancer.

"It's gratifying that two of the presentations reported today provide us with new options to improve survival for patients with advanced castrate-resistant prostate cancer, an especially difficult disease with few effective treatments," said Nicholas J. Vogelzang, MD, Chair and Medical Director of the Developmental Therapeutics Committee of US Oncology, who moderated today's presscast. "Just as importantly, today's studies will help guide our use of several established treatments in the field, ensuring that more patients receive the best possible therapies while avoiding unnecessary side effects and costs."

Genitourinary cancers include those of the prostate, kidney, bladder and testis, as well as less common cancers such as those of the penis, ureters and other urinary organs. In 2012, more than 390,000 people in the United States are expected to be diagnosed with genitourinary cancers, with more than an estimated 58,000 deaths. The most common genitourinary cancer is prostate cancer, which according to estimates, will be diagnosed in more than 241,000 men in the United States in 2012, and claim more than 28,000 lives.*


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Contact: Susie Tappouni
susie.tappouni@asco.org
571-483-1355
American Society of Clinical Oncology
Source:Eurekalert

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