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Research from the 2012 Genitourinary Cancers Symposium highlights new treatments, compares existing therapies for prostate cancer
Date:1/31/2012

ALEXANDRIA, Va. Research on promising new therapies and data on the relative benefits of established treatments for prostate cancer were released today, in advance of the fourth annual Genitourinary Cancers Symposium, being held February 2-4, 2012, at the San Francisco Marriott Marquis in San Francisco, Calif.

The results of five studies were highlighted in a media presscast (press briefing via live webcast):

1) Vigorous Exercise Linked to Expression of Certain Genes in Early-Stage Prostate Cancer: A study shows that men with early-stage prostate cancer who exercise vigorously at least three hours a week have more than 180 genes that are expressed differently in the prostate than those who did not exercise as intensively. These genes include known tumor suppressor genes and DNA repair pathways, suggesting a number of potential mechanisms by which vigorous exercise may help delay cancer progression, as prior studies have shown.

2) IMRT Better Than Conformal Radiation Therapy for Reducing Prostate Cancer Recurrence and Side Effects, May Also Be Superior to Proton Beam Therapy: A large comparative effectiveness study shows that men with localized prostate cancer who are treated with intensity modulated radiation therapy (IMRT) are less likely to experience cancer recurrence or significant side effects from treatment than those who receive conventional conformal radiation therapy (CRT). The analysis also found that proton beam therapy, a newer and more costly form of radiation treatment, did not significantly improve outcomes compared to IMRT.

3) External Beam Radiation Leads to Most Side Effects, Highest Costs of Three Common Prostate Cancer Treatments: An analysis of more than 100,000 prostate cancer patients shows that treatment with external beam radiation therapy (EBRT) resulted in higher long-term toxicities and treatment-related costs than prostatectomy and brachytherapy, two other common treatments for the disease.


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Contact: Susie Tappouni
susie.tappouni@asco.org
571-483-1355
American Society of Clinical Oncology
Source:Eurekalert

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