Navigation Links
Research from the 2012 Genitourinary Cancers Symposium highlights new treatments, compares existing therapies for prostate cancer
Date:1/31/2012

ALEXANDRIA, Va. Research on promising new therapies and data on the relative benefits of established treatments for prostate cancer were released today, in advance of the fourth annual Genitourinary Cancers Symposium, being held February 2-4, 2012, at the San Francisco Marriott Marquis in San Francisco, Calif.

The results of five studies were highlighted in a media presscast (press briefing via live webcast):

1) Vigorous Exercise Linked to Expression of Certain Genes in Early-Stage Prostate Cancer: A study shows that men with early-stage prostate cancer who exercise vigorously at least three hours a week have more than 180 genes that are expressed differently in the prostate than those who did not exercise as intensively. These genes include known tumor suppressor genes and DNA repair pathways, suggesting a number of potential mechanisms by which vigorous exercise may help delay cancer progression, as prior studies have shown.

2) IMRT Better Than Conformal Radiation Therapy for Reducing Prostate Cancer Recurrence and Side Effects, May Also Be Superior to Proton Beam Therapy: A large comparative effectiveness study shows that men with localized prostate cancer who are treated with intensity modulated radiation therapy (IMRT) are less likely to experience cancer recurrence or significant side effects from treatment than those who receive conventional conformal radiation therapy (CRT). The analysis also found that proton beam therapy, a newer and more costly form of radiation treatment, did not significantly improve outcomes compared to IMRT.

3) External Beam Radiation Leads to Most Side Effects, Highest Costs of Three Common Prostate Cancer Treatments: An analysis of more than 100,000 prostate cancer patients shows that treatment with external beam radiation therapy (EBRT) resulted in higher long-term toxicities and treatment-related costs than prostatectomy and brachytherapy, two other common treatments for the disease.

4) Novel Investigational Drug Targeting Bone Metastases Improves Survival for Metastatic Prostate Cancer: A randomized, phase III trial shows that a new radiation-emitting agent aimed at treating bone metastases both improved survival and delayed cancer-related bone problems in men with castration-resistant prostate cancer (CRPC). The agent, radium-223 chloride, is the first alpha particle emitting agent targeting bone metastases shown to improve survival in metastatic CRPC.

5) Study Shows New Targeted Drug Improves Overall Survival in Metastatic Prostate Cancer: An international, randomized phase III trial shows for the first time that an investigational oral drug that halts androgen signaling significantly improves overall survival in patients with metastatic castration-resistant prostate cancer.

"It's gratifying that two of the presentations reported today provide us with new options to improve survival for patients with advanced castrate-resistant prostate cancer, an especially difficult disease with few effective treatments," said Nicholas J. Vogelzang, MD, Chair and Medical Director of the Developmental Therapeutics Committee of US Oncology, who moderated today's presscast. "Just as importantly, today's studies will help guide our use of several established treatments in the field, ensuring that more patients receive the best possible therapies while avoiding unnecessary side effects and costs."

Genitourinary cancers include those of the prostate, kidney, bladder and testis, as well as less common cancers such as those of the penis, ureters and other urinary organs. In 2012, more than 390,000 people in the United States are expected to be diagnosed with genitourinary cancers, with more than an estimated 58,000 deaths. The most common genitourinary cancer is prostate cancer, which according to estimates, will be diagnosed in more than 241,000 men in the United States in 2012, and claim more than 28,000 lives.*


'/>"/>

Contact: Susie Tappouni
susie.tappouni@asco.org
571-483-1355
American Society of Clinical Oncology
Source:Eurekalert

Related medicine news :

1. Embedded Mobile & M2M Device revenues to Rise to Almost $19 Billion Globally by 2014, Says Juniper Research
2. 2010 HSR Impact Award recognizes surgical safety research
3. MSU launches first anti-counterfeiting research program
4. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
5. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
6. Researchers discover new way to kill pediatric brain tumors
7. Family Research Council: Planned Parenthood Report Oversexualizes Ten-Year-Olds, Undermines Parental Authority
8. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
9. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
10. International Diabetes Federation awards $2 million to 9 global diabetes research projects
11. Gladstones Robert Mahley to receive Research!America advocacy award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... ... a crisis. Her son James, eight, was out of control. Prone to extreme mood shifts ... upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife ... and say he was going to kill them. If we were driving on the ...
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... ... 2016 , ... People across the U.S. are sharpening their pencils and honing ... contest in which patients and their families pay tribute to a genetic counselor by ... Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In ...
(Date:6/24/2016)... ... 24, 2016 , ... The Haute Beauty Network, affiliated with ... as a prominent plastic surgeon and the network’s newest partner. , Dr. ... handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands by ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... FRANCISCO, Calif. , June 24, 2016 /PRNewswire/ ... ), a biopharmaceutical company developing novel therapeutics for ... unmet needs, today announced the closing of its ... of common stock, at the public offering price ... in the offering were offered by GBT. GBT ...
(Date:6/24/2016)... , June 24, 2016 The Academy of ... recommendations that would allow biopharmaceutical companies to ... entities that make formulary and coverage decisions, a move ... of new medicines. The recommendations address restrictions ... appear on the drug label, a prohibition that hinders ...
(Date:6/24/2016)... -- According to a new market research ... Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, 8mm, ... Purchase (Retail, Non-Retail) - Trends & Global Forecasts to ... for the forecast period of 2016 to 2021. This ... 2021 from USD 1.65 Billion in 2016, growing at ...
Breaking Medicine Technology: