Navigation Links
Research finds newer radiation therapy technology improves patients' quality of life
Date:1/26/2012

(SACRAMENTO, Calif.) -- Patients with head and neck cancers who have been treated with newer, more sophisticated radiation therapy technology enjoy a better quality of life than those treated with older radiation therapy equipment, a study by UC Davis researchers has found.

The findings, presented today at the Multidisciplinary Head and Neck Cancer Symposium in Phoenix, is the first of its kind to measure long-term quality of life among cancer patients who have undergone radiation therapy for advanced cancers of the throat, tongue, vocal cords, and other structures in the head and neck.

Allen Chen, assistant professor and director of the residency and fellowship training program in the UC Davis Department of Radiation Oncology, reported that the use of intensity-modulated radiation therapy, or IMRT, was associated with fewer long-term side effects, which led to a better quality of life. Standard radiation therapy to the head and neck has been known to affect a patient's ability to produce saliva, taste, and even chew food. These side effects historically have resulted in permanent disabilities.

"With the newer machines using IMRT, physicians are skillfully able to deliver higher doses of radiation to the tumor and lower doses to surrounding normal tissues than ever before," Chen said. "I wanted to see if this theoretical advantage resulted in any tangible improvements in quality of life for patients."

For the study, Chen used the University of Washington Quality of Life instrument, a standardized, previously validated questionnaire that patients complete after radiation therapy. The survey was administered prospectively to 155 patients at UC Davis Cancer Center diagnosed with head and neck cancers, 54 percent of whom were initially treated with IMRT and 46 percent of whom were treated with other radiation therapy technologies. All of the patients receiving IMRT also underwent image-guided radiotherapy (IGRT), which has been available at UC Davis since 2006 and is used to increase accuracy by taking a high-quality scan of the tumor daily.

Chen and his colleagues found that the early gains observed in quality of life became magnified over time for those who received IMRT treatment. For example, one year after treatment, 51 percent of the IMRT patients rated their quality of life as very good or outstanding, compared to 41 percent of non-IMRT patients. But two years after treatment, the percentages changed to 73 percent and 49 percent respectively.

John Torres of Sacramento was diagnosed in early 2010 with a large tumor at the base of his tongue on the right side of his throat. Fearing that surgery might result in the loss of his voice box, Torres opted for IMRT with IGRT and had 33 treatments.

Torres, now 73 and in remission, points out that the treatments were "no walk in the park," but said he is faring much better than he expected. Although his mouth is often dry and he has lost some taste sensation, he is enjoying an active life.

"I golf a couple of time a week," he said. "My wife and I like to socialize. We go out, and we dance. And we are planning to take a cruise through the Panama Canal in next two or three months. Life has gotten back to pretty much exactly what it was."

Chen acknowledged that quality of life is difficult to measure because of its subjective nature. Nonetheless, he said the findings support the more widespread use of IMRT in radiation clinics throughout the country.

"There has been some reluctance to utilize it because it is expensive, resource intensive, and takes on average 10 to 12 hours to prepare a single patient's treatment," he said. "I think this is further evidence that our investment in developing newer technologies is really paying off."


'/>"/>
Contact: Dorsey Griffith
dorsey.griffith@ucdmc.ucdavis.edu
916-734-9118
University of California - Davis Health System
Source:Eurekalert

Related medicine news :

1. Embedded Mobile & M2M Device revenues to Rise to Almost $19 Billion Globally by 2014, Says Juniper Research
2. 2010 HSR Impact Award recognizes surgical safety research
3. MSU launches first anti-counterfeiting research program
4. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
5. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
6. Researchers discover new way to kill pediatric brain tumors
7. Family Research Council: Planned Parenthood Report Oversexualizes Ten-Year-Olds, Undermines Parental Authority
8. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
9. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
10. International Diabetes Federation awards $2 million to 9 global diabetes research projects
11. Gladstones Robert Mahley to receive Research!America advocacy award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... temporary closing of Bruton Memorial Library on June 21 due to a possible lice infestation, ... aspect of head lice: the parasite’s ability to live away from a human host, and ... necessary one in the event that lice have simply gotten out of control. , As ...
(Date:6/25/2016)... ... 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the ... to iHire in recognition of their exemplary accomplishments in worksite health promotion. , The ... Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... ... ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for ... $12 an hour by 2020 and then adjusting it yearly to increase at the same ... wage, assure the wage floor does not erode again, and make future increases more predictable. ...
(Date:6/24/2016)... ... 2016 , ... Strategic Capital Partners, LLC (SCP) in concert ... capital for emerging technology companies. SCP has delivered investment events and professional ... than a million dollars of capital investment for five companies. The ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016 /PRNewswire/ ... pulmonary function testing company, is now able to perform sophisticated lung ... ndd Medical Technologies , Inc. Patients are ... labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients like ... any needed testing done in the comfort of her own home. ...
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
(Date:6/23/2016)... June 23, 2016  MedSource announced today that ... e-clinical software solution of choice.  This latest decision ... value to their clients by offering a state-of-the-art ... relationship establishes nowEDC as the EDC platform of ... full-service clients.  "nowEDC has long been a preferred ...
Breaking Medicine Technology: