Navigation Links
Research finds gallium nitride is non-toxic, biocompatible - holds promise for implants
Date:10/24/2011

Researchers from North Carolina State University and Purdue University have shown that the semiconductor material gallium nitride (GaN) is non-toxic and is compatible with human cells opening the door to the material's use in a variety of biomedical implant technologies.

GaN is currently used in a host of technologies, from LED lighting to optic sensors, but it is not in widespread use in biomedical implants. However, the new findings from NC State and Purdue mean that GaN holds promise for an array of implantable technologies from electrodes used in neurostimulation therapies for Alzheimer's to transistors used to monitor blood chemistry.

"The first finding is that GaN, unlike other semiconductor materials that have been considered for biomedical implants, is not toxic. That minimizes risk to both the environment and to patients," says Dr. Albena Ivanisevic, who co-authored a paper describing the research. Ivanisevic is an associate professor of materials science and engineering at NC State and associate professor of the joint biomedical engineering program at NC State and the University of North Carolina at Chapel Hill.

Researchers used a mass spectrometry technique to see how much gallium is released from GaN when the material is exposed to various environments that mimic conditions in the human body. This is important because gallium oxides are toxic. But the researchers found that GaN is very stable in these environments releasing such a tiny amount of gallium that it is non-toxic.

The researchers also wanted to determine GaN's potential biocompatibility. To do this they bonded peptides the building blocks that make up proteins to the GaN material. Researchers then placed peptide-coated GaN and uncoated GaN into cell cultures to see how the material and the cells interacted.

Researchers found that the peptide-coated GaN bonded more effectively with the cells. Specifically, more cells bonded to the material and those cells spread over a larger area.

"This matters because we want materials that give us some control over cell behavior," Ivanisevic says. "For example, being able to make cells adhere to a material or to avoid it.

"One problem facing many biomedical implants, such as sensors, is that they can become coated with biological material in the body. We've shown that we can coat GaN with peptides that attract and bond with cells. That suggests that we may also be able to coat GaN with peptides that would help prevent cell growth and keep the implant 'clean.' Our next step will be to explore the use of such 'anti-fouling' peptides with GaN."


'/>"/>
Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University
Source:Eurekalert  

Related medicine news :

1. Embedded Mobile & M2M Device revenues to Rise to Almost $19 Billion Globally by 2014, Says Juniper Research
2. 2010 HSR Impact Award recognizes surgical safety research
3. MSU launches first anti-counterfeiting research program
4. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
5. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
6. Researchers discover new way to kill pediatric brain tumors
7. Family Research Council: Planned Parenthood Report Oversexualizes Ten-Year-Olds, Undermines Parental Authority
8. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
9. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
10. International Diabetes Federation awards $2 million to 9 global diabetes research projects
11. Gladstones Robert Mahley to receive Research!America advocacy award
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Research finds gallium nitride is non-toxic, biocompatible - holds promise for implants
(Date:5/23/2017)... ... May 23, 2017 , ... PM360, the premier information ... announced the winners of its 3rd Annual ELITE Awards. The ELITE (Exceptional • ... the healthcare industry today. , Out of more than 500 submissions, 100 winners ...
(Date:5/23/2017)... ... May 23, 2017 , ... London, May 23, 2017: Walter Schindler, ... this month as a Guest Speaker and Contributor to a weeklong series of classes, ... Purpose. , Walter Schindler and SAIL Capital have received ...
(Date:5/23/2017)... ... May 23, 2017 , ... ... chat as a standard feature on its secure clinical communication platform. The platform ... to video depending on the type and urgency of a situation. , ...
(Date:5/23/2017)... ... May 23, 2017 , ... Therachat , a smart guided journaling ... infographic on the current state of anxiety in support of National Mental Health Awareness ... in April 2017 and benchmarked general anxiety levels as well as identified the top ...
(Date:5/22/2017)... ... May 22, 2017 , ... Today, Our Urgent Care ... with a public ribbon cutting ceremony. Since opening over a month ago, ... to the emergency room. The new Our Urgent Care walk-in clinic is located ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... May 10, 2017 Hologic, Inc. (Nasdaq: ... for the fiscal second quarter ended April 1, 2017 ... $1.84 increased 666.7% compared to the prior year period ... in a significant gain, while non-GAAP diluted EPS of ... or 3.8% in constant currency terms.  Excluding the effects ...
(Date:5/9/2017)... , May 9, 2017 Zimmer Biomet Holdings, ... musculoskeletal healthcare, today announced it has earned a spot ... 2017" list. The Company was ranked among 500 U.S. ... Employers and Healthcare Equipment and Services. The ... on an anonymous, independent survey of over 30,000 employees ...
(Date:5/8/2017)... May 8, 2017  Diplomat Pharmacy, Inc. (NYSE: DPLO)., ... ("WRB"), a health care service center company based ... WRB specializes in relationship management programs for leading pharmaceutical ... WRB will join Envoy Health ... services for manufacturers, biotech firms, and other service companies. ...
Breaking Medicine Technology: