Navigation Links
Research findings may lead to new ways to study and fight diabetes
Date:2/14/2008

COLLEGE STATION Diabetes can be a killer, but the recent findings of four Texas A&M University researchers could lead to new ways to study and fight the dreaded disease.

Diabetics not only have high blood glucose (sugar) levels, they also have elevated fatty acid levels because they have trouble metabolizing glucose and fatty acids. In the past, scientists have studied the glucose and fatty acid aspects of diabetes separately because there was nothing linking them together.

Texas A&M researchers Heather Hostetler, Huan Huang, Ann Kier, and Friedhelm Schroeder, however, were able to link the two areas of study by identifying a single molecule in the nucleus of cells that regulates the metabolism of both glucose and fatty acids. The results of their study were recently published in the Journal of Biological Chemistry.

Scientists have long known that fatty acids bind with a protein called PPAR-alpha in the nucleus of cells. PPAR-alpha is a nuclear receptor, which means it is responsible for regulating the expression of specific genes. When fatty acids bind to PPAR-alpha, certain genes are turned on or off to control the metabolism of fatty acids.

Hostetler and her colleagues recently found that glucose also binds to PPAR-alpha, which presents an opportunity for scientists to study and understand one mechanism that regulates both glucose and fatty acid metabolism.

This provides a direct link for the first time between fat and sugar metabolism and shows they are intimately linked and share the same receptor in the nucleus, Schroeder said. This could be a paradigm-shifter and cause people to rethink the way they look at diabetes because we now have a central player PPAR-alpha thats impacted by both glucose and fatty acids.

Normally, a hormone called insulin signals a persons cells to take in and metabolize glucose. In diabetics, however, either not enough insulin is being produced or the persons insulin recept
'/>"/>

Contact: Keith Randall
keith-randall@tamu.edu
979-845-4644
Texas A&M University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... 2015 Spring and summer are popular ... visiting family for the holidays or simply taking vacations. ... to travel can be a difficult choice. Pet-friendly accommodations ... pets is becoming a more common option. Royal ... stay at pet-friendly accommodations a positive experience. , 1.) ...
(Date:4/21/2015)... CA (PRWEB) April 21, 2015 “The warm ... SunGrubbies.com. “Doesn’t every mother want to look younger than her ... is the first line of defense. Signs of ... are the evidence of too much time spent in the ... only reason to cover up. The dangers of UV ...
(Date:4/20/2015)... Virginia (PRWEB) April 20, 2015 ... Health facility in Stuarts Draft, an independent, nonprofit ... Staunton, and Waynesboro, Virginia. The project was an ... The Stuarts Draft facility is expected to provide ... Located on Stuarts Draft Highway, the new facility ...
(Date:4/20/2015)... NOVI, Mich. (PRWEB) April 21, 2015 ... sisters, daughters and girlfriends at the twentieth annual Michigan ... Collection Showplace in Novi. , “There is lots to ... cooking demonstration to shopping for fashion and gifts,” said ... three stages are entertaining and encouraging with appearances from ...
(Date:4/20/2015)... Global Lyme Alliance (GLA) announced today that its ... Hyatt Regency Greenwich, raised over $850,000 to fund research ... tick-borne diseases. , “We are extremely grateful to ... this year’s Gala such a success,” said Robert Kobre, ... initiatives to ultimately find a cure for Lyme ...
Breaking Medicine News(10 mins):Health News:Royal Flush Havanese Announces 5 Tips for a Successful Stay in Pet-Friendly Accommodations 2Health News:Royal Flush Havanese Announces 5 Tips for a Successful Stay in Pet-Friendly Accommodations 3Health News:Royal Flush Havanese Announces 5 Tips for a Successful Stay in Pet-Friendly Accommodations 4Health News:Sun’s the Word this Mother’s Day Say’s SunGrubbies.com, a Leading Retailer of Sun Protection Products 2Health News:Augusta Health Construction Wraps Up at Stuarts Draft 2Health News:Perfect Girls Day Out at Michigan International Women’s Show Opening Thursday, April 30 in Novi Presented by Southern Shows 2Health News:Perfect Girls Day Out at Michigan International Women’s Show Opening Thursday, April 30 in Novi Presented by Southern Shows 3Health News:Global Lyme Alliance's “Time for Lyme” Gala Raises Over $850,000 for Tick-Borne Disease Research 2Health News:Global Lyme Alliance's “Time for Lyme” Gala Raises Over $850,000 for Tick-Borne Disease Research 3
... Hospital and Columbia University Medical Center has led the ... HIV.// He is lead author and chair of the ... treatment of the disease in developed nations—presented on Aug. ... and published in the Aug. 16 Journal of the ...
... scientists childhood allergies are increasing around the world, even ... eczema have become serious// public health issues. ... being hospitalized or even dying. ,Although the ... inflammation of the airways, it is still unknown what ...
... maternity hospital was diagnosed with deadly whooping cough. As a ... as a precautionary measure. ,This woman was working ... in Camperdown. The Sydney South West Area Health Service had ... staff member ceased all contact with patients and families immediately,' ...
... epidemic of this season. This disease seems to have overshadowed ... the viral disease had been reported from Tamil Nadu, Karnataka, ... last 2 years. In Tamil Nadu alone, 49,567 people have ... · Aedes aegypti mosquito is 60 % higher than ...
... not to give unpasteurized apple juice or other unpasteurized products ... Even the elderly and people with weak immune systems are ... is that such products contain Salmonella and E. coli, which ... also said that a majority of juice n the country ...
... project that will test the clinical efficacy of Ayurvastra, ... herb// concoctions." The project was launched at the Government ... project was started by the Directorate of Handloom, Department ... Vijnan, Government Ayurveda College. The project aims to start ...
Cached Medicine News:Health News:Dr. Scott Hammer Authors Two New Guidelines for HIV Treatment 2Health News:World wide Increase in Childhood Allergies 2Health News:Beware of Chikungunya !! 2
(Date:4/20/2015)... is the daily "Profile America" feature from the U.S. ... Profile America — Tuesday, April 21st. One ... for general use this month in 1923, saving the ... is a hormone produced by the pancreas and is ... body. It was first isolated the year before by ...
(Date:4/20/2015)... 20, 2015 Actavis plc (NYSE: ... Mayr , Chief Communications Officer, will retire from ...  In conjunction with Mayr,s retirement, Alex Kelly ... of Chief Communications Officer, effective immediately. Prior to ... Vice President, Chief Communications Officer, Public Affairs and ...
(Date:4/20/2015)... , April 20, 2015   Precision Image ... series designed to highlight advances in cardiovascular imaging and ... president of the Society for Cardiovascular Magnetic Resonance ... will highlight improvements in patient management by providing broader ... presentation will help attendees to better understand appropriate use ...
Breaking Medicine Technology:U.S. Census Bureau Daily Feature for April 21 2Actavis Announces Retirement of Charles M. Mayr 2Actavis Announces Retirement of Charles M. Mayr 3Educational Webinar Teaches Improved Patient Management Through Broader Access to Cardiac MRI 2
... - Neose Technologies,Inc. (Nasdaq GM:NTEC) today ... with its collaborative partner, Novo Nordisk ... at the XXIst,Congress of the International ... Switzerland. The data presented demonstrates that,GlycoPEGylation(TM) ...
... On Wednesday,July 11, 2007, at 1:30 p.m. ... of Cell Therapeutics, Inc.'s (CTI),management team will ... of the interim results of its phase ... which pixantrone is substituted for,doxorubicin in standard ...
Cached Medicine Technology:Neose Announces Presentation of Positive Preclinical Data on,GlycoPEGylated Factor VIIa at the XXI Congress of the International,Society on Thrombosis and Haemostasis 2Cell Therapeutics, Inc. Management to Discuss Today's Announcement,of Interim Pixantrone Study Results 2
Reliavac 100cc evacuators offer a more constant suction profile than silicone evacuators. 100cc capacity is easy for patient to carry. Bottom emptying port reduces chance of contamination....
100cc silicone evacuator...
Single round silicone drain with 10 in. hole pattern, 49 in. long...
Siliconized PVC drains...
Medicine Products: