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Research explores lung cancer among pediatric cancer patients
Date:11/1/2010

age, we were reluctant to call such tumors 'BAC' and instead qualified these cases as 'BAC-like nodule,'" explained lead investigator, Dr. Marc Ladanyi of Memorial Sloan-Kettering Cancer Center. "Our findings now confirm the presence of EGFR and KRAS mutations in some of these pediatric lung cancers in a proportion similar to lung cancers seen in adults, which allows us to more confidently propose that this is genuine lung cancer in the pediatric population. The clinical course of these lung adenocarcinomas in children remains unclear because all 8 patients had their lung tumors fully removed without subsequent recurrence. This may reflect the fact that half of the patients had AIS, which is now recognized to have a 100 percent disease free survival for completely resected cases. An open question is whether these lung adenocarcinomas are increasing in the pediatric age group or is this due to a detection bias due to more detailed lung imaging in patients with common, non-pulmonary, childhood cancers."


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Contact: Kaitlin Doody
kdoody@spectrumscience.com
202-587-2553
International Association for the Study of Lung Cancer
Source:Eurekalert

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