Navigation Links
Research defines timeframes, factors to deem early stage lung cancer cured
Date:8/2/2010

In patients with non-small cell lung cancer (NSCLC), five-year disease-free survival is currently the benchmark of cure. However, there are two issues that remain with the follow-up standards: (1) When can cure be declared with confidence and (2) for how long should follow-up examination be continued?

In order to define a strategy for long-term follow-up for early stage lung cancer patients, research published in the August edition of the Journal of Thoracic Oncology (JTO) quantified the risk of late recurrence in patients with stage IA NSCLC who remained recurrence-free for more than five years after complete tumor resection. Overall, the findings indicate that in patients with stage IA NSCLC without vascular invasion (cancer cells within blood vessels), five years may be sufficient to declare that the patients are cured. In contrast, patients with stage IA NSCLC with vascular invasion need follow-up until at least nine years after resection.

In this study, the research team identified a total of 519 patients with stage IA NSCLC who underwent complete resection between August 1992 and December 2002. Recurrence-free probability was measured from the benchmark of five years after primary tumor resection to the date of first recurrence or last follow-up. Of the 519 patients, 434 remained recurrence-free for the first five years. Among these, only 21 (4.8 percent) developed late recurrence more than five years after resection.

The researchers identified one independent significant predictor of late recurrence in stage IA five-year recurrence-free survivors: the presence of vascular invasion. The five-year recurrence-free probability from the benchmark was 84 percent for patients with vascular invasion and 95 percent for patients without vascular invasion.

Summarizing the findings, lead investigator, Ryo Maeda, MD, explains that "If they are recurrence-free, patients without vascular invasion may be declared cured at five years after resection. On the other hand, patients with stage IA NSCLC with vascular invasion, five years without recurrence is not sufficient to conclude that NSCLC is cured."


'/>"/>

Contact: Megan Richter
mrichter@spectrumscience.com
202-587-2556
International Association for the Study of Lung Cancer
Source:Eurekalert  

Related medicine news :

1. Women attracted to men in red, research shows
2. Researchers develop advanced search tool to help physicians sort and retrieve vital EMR data
3. Reality TV, cosmetic surgey linked, says Rutgers-Camden researcher
4. MSU targets womens health research with $2.5 million grant
5. Researchers identify key enzyme in DNA repair pathway
6. A breakthrough in tuberculosis research
7. Researchers study benefits of white button mushrooms
8. AWARD Fellowship highlights critical role of African women in agricultural research
9. Use of decision-aid program increases safety for women experiencing abuse, researchers find
10. Trainee publication highlights success of US-China agricultural injury research training project
11. Researchers uncover biological rationale for why intensive lupus treatment works
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Research defines timeframes, factors to deem early stage lung cancer cured
(Date:6/20/2017)... ... 20, 2017 , ... New, state-of-the-art magnetic resonance imaging (MRI) ... with advanced capabilities for diagnosing and treating disease. , Jefferson’s Siemens Magnetom ... get a more accurate look inside the patient’s body. The new scanner was ...
(Date:6/20/2017)... ... June 20, 2017 , ... Uniform Advantage (UA), ... seven new products designed to create tailored looks and athleisure-inspired outfits. UA Flex fabric ... easy care stretch twill. , With trendy looks hitting the medical community, UA Flex ...
(Date:6/20/2017)... (PRWEB) , ... June 20, 2017 , ... Uniworld ... of living” aboard the line’s latest all-inclusive boutique ship, S.S. Joie de Vivre ... was built specifically for cruising France’s Seine River and designed small enough to dock ...
(Date:6/20/2017)... TX (PRWEB) , ... June 20, 2017 , ... ... that Michael McKenna has joined the company as Vice President of Sales, a ... company for continued growth and increased customer satisfaction. , Mr. McKenna is a ...
(Date:6/19/2017)... ... June 19, 2017 , ... Intrinsic Clinical ... the international exchange of actionable insights to improve health globally through the advancement ... make clinical trial management faster, easier, and less painful. Attendees can visit Intrinsic’s ...
Breaking Medicine News(10 mins):
(Date:6/8/2017)... , June 8, 2017  StatLab ... leading developer and manufacturer of diagnostic supplies ... today that Cressey & Company LP ("Cressey ... has completed a growth-focused investment in the ... majority ownership position from selling shareholder, Prairie ...
(Date:6/5/2017)... June 5, 2017 Kohll,s Pharmacy & Homecare is the ... the United States . The Raizer is a simple ... person up to an almost-standing position within a ... by one assistant and does not require any ... that a child can operate it, and lightweight ...
(Date:5/30/2017)... , May 30, 2017 Hill-Rom Holdings, Inc. ... Annual Global Healthcare Conference on Tuesday, June 13, 2017, ... John Greisch , Hill-Rom,s president and chief executive officer, is ... The live audio webcast can be accessed at http://ir.hill-rom.com/events.cfm ... conclusion of the live event through September 13, 2017. ...
Breaking Medicine Technology: