Navigation Links
Research collaboration seeks blood test for aggressive breast cancer
Date:4/16/2008

, lead investigator on the proteomics half of the project.

The cancer indicators they are seeking are proteins that arise from genes that have run amuck in cancer. Comparing proteins that work in cancer cells to those in normal cells might reveal how the cells maintain and disperse the cancer throughout the body.

"The genes are the generals giving orders. And those proteins are the foot soldiers who take those orders and accomplish the goal based on the local conditions they find," says Shriver. "Until we know what's going on at the protein level, we don't know how the orders are being applied in the cells."

In addition to finding a tool to fight cancer, Shriver says, the project will likely suggest details of the inner workings of breast cancer cells.

"Hunting for biomarkers is a difficult process," adds geneticist Richard Mural, chief scientific officer at Windber. "But this project will generate unique and new data."

The military might seem an odd place to turn to study what largely afflicts women, but a fifth of the Army's active duty contingent are women, and many of the rest are married to women. In concert with Windber, the Army opened the Clinical Breast Care Project in 2001 to focus solely on breast health to assure the well-being of the force. Since then, they have collected more than 30,000 breast cancer and blood samples from about 4000 female patients.

The clinical sample collection is one key to the project's success, the researchers say. The samples follow the course of the disease, which is one of the best ways to track the growth and spread of cancer, says Mural. Blood samples have been collected before and after surgical treatment, and workers gather the clinical and family histories from the women. Pathologists examine the cancer tissue and the samples are handled and stored under strict protocols, Mural says.

The team will compare the proteins of cancers that stayed in the breast to
'/>"/>

Contact: Mary Beckman
mary.beckman@pnl.gov
509-375-1019
DOE/Pacific Northwest National Laboratory
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. OHSU Cancer Institute researchers discover key gene involvement in cancer development
2. IU Health & Wellness: New research findings from the Kinsey Institute
3. The Pancreatic Cancer Action Network Announces Its 2008 Research Grant Awards Totaling Over $1 Million in New Research Funding
4. Key Vioxx Research Was Written by Merck, Documents Allege
5. Combining liver cancer treatments doubles survival rates, UVA researchers find
6. AUDIO from Medialink and Apple Products Research and Education Council: New Research -- Adults Who Eat Apples, Apple Juice Have Healthier Diets and Lower Risk for Metabolic Syndrome
7. Lake Hospital System Selected as Pilot Site for Health Information Literacy Research Project
8. New National Research Center Focuses on Treatment and Prevention of Sports and Exercise Injuries
9. Leading HIV researchers to collaborate on vaccine development
10. Sunesis Pharmaceuticals Presents Nonclinical Data on SNS-595 at the Annual Meeting of the American Association for Cancer Research
11. American Cancer Society awards research grants to 133 investigators at 84 institutions nationwide
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... worsen the symptoms of MS, say researchers, who have zeroed ... development of novel strategies// to treat this severe neurological disease, ... ,The study has indicted that an exercise ... managing the signal, might be the key to unlock a ...
... his ministry views the contamination of soft drinks with utmost ... taken note of the studies carried out by Centre for ... the print and electronic media on Aug 2. The report ... ,The ministry views "the contamination of soft drinks with ...
... Kerala's ruling Left Democratic Front (LDF) urging Chief Minister V.S. ... in the state// , the humble tender coconut may finally ... being available in plenty in the state, sales have been ... aerated soft drinks from Pepsi and Coca-Cola creating a furore ...
... at Washington University School of Medicine in St. Louis have ... high blood pressure get less energy because of their reduced ... recent issue of the Journal of Nuclear Cardiology. ,"The ... the body," says Lisa de las Fuentes, M.D. ,Earlier ...
... understand how IVIG worked. Its ability to treat autoimmune ... ,Intravenous immunoglobulin (IVIG) is a complex mixture of ... pooled antibodies from thousands of people, and is only ... have used it off-label with varied success in patients ...
... telephonic survey conducted by Dr. David Schutt of Thomson Medstat, ... than three-quarters// of Americans who are obese think their eating ... by phone and the participants said that they did vigorous ... people said that they snacked two or more times a ...
Cached Medicine News:Health News:Fat Metabolism Of Heart Muscles Affected By High Blood Pressure 2Health News:Fat Metabolism Of Heart Muscles Affected By High Blood Pressure 3Health News:Single Sugar Enables Antibody to Treat Inflammation 2Health News:Single Sugar Enables Antibody to Treat Inflammation 3
(Date:1/14/2014)... HILLSBORO, Ore. , Jan. 14, 2014 /PRNewswire-iReach/ -- ... and a targeting guide with accompanying instrumentation to place ... new adjunct to the soft tissue (e.g. ligament) repair ... soft tissue repair heals. (Photo: http://photos.prnewswire.com/prnh/20140114/MN45636 ... to maintain the anatomical reduction (spacing) of the scaphoid ...
(Date:1/14/2014)... , Jan. 14, 2014 NineSigma , ... hold its Innovation Leadership Summit , May 14-16, ... Cleveland Ohio . ... and organizations committed to breakthrough achievements through open innovation. ... through unobvious connections, across disciplines and even across industries. ...
(Date:1/14/2014)... 14, 2014   Evidera , a leading ... announced that the Center for Drug Evaluation and ... released its first draft qualification guidance document for ... Qualification of Exacerbations of Chronic Pulmonary Disease ... Bacterial Exacerbation of Chronic Bronchitis in Patients With ...
Breaking Medicine Technology:Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 3Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 3Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 4Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 2Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 3Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 4
... CHICAGO, Oct. 7 A new women,s health, whole ... frequency of moderate to severe hot flashes and reduced ... its kind among postmenopausal U.S. women, according to peer-reviewed ... American Menopause Society (NAMS) Annual Meeting.  Also, the first ...
... Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX ) ... Application (NDA) filing for carfilzomib based on a recent ... division of the U.S. Food and Drug Administration (FDA). ... commercial-scale manufacturing of carfilzomib.  Onyx had previously anticipated filing ...
Cached Medicine Technology:New Soy-Based Natural S-equol Supplement Reduces Menopausal Hot Flashes, Muscle and Joint Pain in First Study Among U.S. Women 2New Soy-Based Natural S-equol Supplement Reduces Menopausal Hot Flashes, Muscle and Joint Pain in First Study Among U.S. Women 3New Soy-Based Natural S-equol Supplement Reduces Menopausal Hot Flashes, Muscle and Joint Pain in First Study Among U.S. Women 4New Soy-Based Natural S-equol Supplement Reduces Menopausal Hot Flashes, Muscle and Joint Pain in First Study Among U.S. Women 5New Soy-Based Natural S-equol Supplement Reduces Menopausal Hot Flashes, Muscle and Joint Pain in First Study Among U.S. Women 6New Soy-Based Natural S-equol Supplement Reduces Menopausal Hot Flashes, Muscle and Joint Pain in First Study Among U.S. Women 7Onyx Pharmaceuticals Provides Status Update on Carfilzomib 2Onyx Pharmaceuticals Provides Status Update on Carfilzomib 3
... System supports approaches to Admitting/Discharge/Transfer ... record keeping functions using a ... facilities and cut across institutional ... community clinics, physician, agency, nursing ...
... Dairylands Clinical Information Management ... suite of integrated applications ... departments and automate administrative ... The applications allow organizations ...
... include a Patient Face Sheet, ... many as six custom tabs, ... information is important for you ... Import Manager utility lets you ...
... WEBeDoctor® Physician-office® is an ... physicians, (Solo practice, group ... to complete their normal ... It is a front ...
Medicine Products: