Navigation Links
Research Yields Clues to Severe Form of Sinusitis
Date:11/23/2009

Obstructive polyps can impair breathing, protein may be the cause

MONDAY, Nov. 23 (HealthDay News) -- U.S. researchers say they've identified a protein that causes nasal and sinus polyps in 15 percent to 30 percent of people with chronic sinusitis.

The condition is one of the most serious forms of sinusitis, a constant irritation and swelling of the nasal passages. Polyps - unhealthy overgrowths of sinus tissue -- can block the sinus passages and make it difficult or impossible to breathe through the nose. This often leads to pain, swelling and infections.

"This type of sinusitis isn't subtle -- you can spot the patients with polyps across the room. They're breathing through their mouths, they talk with nasal voices, they're constantly sniffling, and their faces are swollen," Dr. Jean Kim, an assistant professor in the departments of otolaryngology and allergy and clinical immunology at the Johns Hopkins University School of Medicine, said in a news release.

Kim and colleagues analyzed sinus tissue from patients and concluded that a protein called vascular endothelial growth factor (VEGF) -- which is known to stimulate blood vessel growth -- causes the cell overgrowth that causes the polyps.

The protein may offer a target for new treatments for the condition, which typically resists all current therapies. Surgery is a common treatment but the polyps nearly always regrow. Oral steroids only temporarily treat the problem and have a number of harmful side effects.

"In the future, we might have a nasal spray with an anti-VEGF agent in it," Kim said.

The study appears in the Dec. 1 issue of the American Journal of Respiratory and Critical Care Medicine.

More information

The U.S. National Institute of Allergy and Infectious Diseases has more about sinusitis.


Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... "I injured my shoulder and had to have ... Sunnyvale, Calif. "When I slept in one, I almost strangled ... and require too many straps. That is why I came ... Vest to improve the design of a standard sling. The ... properly. This helps to speed up the healing process. The ...
(Date:7/28/2014)... HealthDay Reporter FRIDAY, July 25, ... policy that bans blood donations from gay and bisexual men, according ... in the Journal of the American Medical Association . ... cannot donate blood in the United States -- a lifetime ban ... and Drug Administration adopted this policy at the dawn of the ...
(Date:7/28/2014)... MONDAY, July 28, 2014 (HealthDay News) -- Following a ... risk for chronic health issues, a new study indicates. ... who survived childhood cancer should be educated ... their health in the future. "These findings are ... for cancer as children have the opportunity to influence ...
(Date:7/28/2014)... "We experienced difficulty filling our pill ... two inventors from Jamestown, Calif. "We came up with ... we could pour medications in more easily." , They ... keep the lids open as the pill box is ... compartments have been filled. This eliminates hassles and frustrations, ...
(Date:7/28/2014)... Scientists in Japan have completed initial ... test for the asbestos cancer mesothelioma. Surviving Mesothelioma has ... Click here to read it now. , Researchers ... University Graduate School of Medicine say a new test ... above the old test. , “Particularly for the ...
Breaking Medicine News(10 mins):Health News:Lift U.S. Ban on Blood Donations by Gay Men, Experts Say 2Health News:Lift U.S. Ban on Blood Donations by Gay Men, Experts Say 3Health News:Healthy Habits May Help Childhood Cancer Survivors Avoid Chronic Ills 2Health News:Test Results Look Promising for New Mesothelioma Blood Test, According to Surviving Mesothelioma 2
... that only aims at malignant cells might fall short ... of normal cells which are present long before any ... is going to be, new research suggests. , Such ... the body, residing innocently there until certain cancer genes ...
... [New Jersey plastic surgeon] Dr. Paul M. Parker has been performing ... months. His patients have loved their sculpted tummies and their quick ... added two significant refinements to the procedure making the results and ... ...
... 5000 survey recognizes Alpharetta-based Company for outstanding growth, and success in ... ... 28, 2008 -- www.jacksonhealthcare.com [Jackson Healthcare] (JH) has been ... of the nation,s fastest growing and most entrepreneurial private companies. ...
... another Major Rise in Listeners. Affordable Health Insurance and Health ... ... City, MO (PRWEB) August 28, 2008 -- The Health Insurance Advocate ... 6th on 1260 AM and 104.1 FM KSGF. The weekly ...
... Volunteer to take part in Signature,Chefs Auction Galas, ... a kitchen near you: Chef Rahman "Rock" Harper will ... Chef Auctions open to the public,nationwide this fall., ... celebrity chef,spokesperson. In this role, Chef Rock, winner of ...
... for Efforts to Create Sensible Fire Safety ... ... have voted to maintain California,s tough fire,standards by striking down proposed fire ... of sensible,legislation to address fire safety regulations in the state. The bill ...
Cached Medicine News:Health News:Normal Cells May Predict Cancer Virulence 2Health News:Lipoabdominoplasty: A New Type of Tummy Tuck Gets Even Better 2Health News:Lipoabdominoplasty: A New Type of Tummy Tuck Gets Even Better 3Health News:Lipoabdominoplasty: A New Type of Tummy Tuck Gets Even Better 4Health News:Jackson Healthcare Ranked 48th of All Health Companies on Inc. Magazine's 2008 List of 5000 Fastest Growing Private Companies 2Health News:The Health Insurance Advocate Radio Show Expands to Springfield, Missouri, and Reaches a New All-Time Ratings High for Female Listenership 2Health News:The Health Insurance Advocate Radio Show Expands to Springfield, Missouri, and Reaches a New All-Time Ratings High for Female Listenership 3Health News:Chef Rock to Rock Signature Chefs Auctions(R) Nationwide 2Health News:California Senate Rejects Proposed Effort to Weaken Fire Safety Standards 2
(Date:7/28/2014)... 28, 2014  Isis Pharmaceuticals, Inc. (NASDAQ: ... 2014 Financial Results and Highlights Conference CallWhen:Monday, August 4 ... How:Live on the Internet. Simply log onto our ... during the live event, a replay of the webcast ... www.isispharm.com . ABOUT ISIS PHARMACEUTICALS, INC. Isis ...
(Date:7/28/2014)... , July 28, 2014 ... £2.5 million to help it meet the global ... healthcare, pharmaceuticals and logistics. Albion joins Shackleton Ventures. ... Over the past 18 months OmPrompt ... platform, its management team and its operations. The ...
(Date:7/25/2014)... July 25, 2014  Depomed, Inc. (NASDAQ: ... quarter fiscal year 2014 financial results after the market ... a conference call beginning at 4:30 pm EDT, 1:30 pm PDT ... the call by dialing 877-317-6789 ( United States ... also be available via a live webcast on the ...
Breaking Medicine Technology:Webcast Alert: Isis Pharmaceuticals' Second Quarter 2014 Financial Results Conference Call 2OmPrompt Funded for Customer Automation Management Market Expansion 2Depomed To Report Second Quarter Fiscal Year 2014 Financial Results On Wednesday, August 6, 2014 2
... Feb. 28, 2012   New Mexico Software, Inc. , d/b/a ... NMXC ), a developer of medical IT solutions and ... community, announced today that the company,s long standing suit brought ... judgment in favor of New Mexico Software. The ...
... 2012   Alexander Orthopaedic Associates (AOA) in Largo, FL, ... their practice with White Plume Technologies between Exscribe ... (ADSC) practice management system (PM system). EMRs ... the billing process unfilled. White Plume Technologies bridges ...
Cached Medicine Technology:New Mexico Software Prevails in Lawsuit 2Alexander Orthopaedic Associates Chooses White Plume Technologies to Fill the EMR Gap 2
Each handle is designed to fit a specific trephine size....
Each handle is designed to fit a specific trephine size....
Each handle is designed to fit a specific trephine size....
Each handle is designed to fit a specific trephine size....
Medicine Products: