Navigation Links
Research Warns of Overuse of Powerful Class of Antibiotics

SUNDAY, April 3 (HealthDay News) -- The use of a powerful class of antibiotics called carbapenems has increased dramatically in the United States over the past five years, a new study shows.

The increased use of these drugs -- widely regarded as the last option for treating severe infections caused by multidrug-resistant bacteria -- is cause for concern because carbapenem-resistant bacteria are becoming more common, the researchers said.

Overuse of carbapenem drugs could lead to the reduction of their effectiveness against tough-to-treat infections.

For this study, the researchers analyzed antibiotic use in 110 VA facilities from 2005 to 2009. They found a gradual rise in overall antibiotic use, but major increases in the use of certain types of antibiotics: carbapenems (102 percent); intravenous vancomycin (79 percent); and combinations of penicillin with beta-lactamase-inhibitors (41 percent).

The investigators also found that fluoroquinolones were the most frequently used class across all the VA facilities, accounting for 20 percent of all antibiotic use.

The study was to be presented Sunday at the Society for Healthcare Epidemiology of America (SHEA) annual meeting, in Dallas.

"Use of these antibiotics helps the patient receiving the treatment, but has future consequences for innocent bystanders. The more these drugs are used, the more resistance we see," study author Dr. Makoto Jones said in a society news release.

"In this era of multidrug-resistant organisms, clinicians are placed in a difficult situation," Dr. Steven Gordon, SHEA president, said in the news release. "As treatment outcomes of many bacterial infections are influenced by the timing of appropriate therapy, the increasing presence of resistant organisms triggers broader use of these powerful antibiotics for proven or suspected infections when treating patients in the hospital."

Gordon added that doctors "must always put the patient first in treatment decisions but we must empower effective antibiotic stewardship programs, infection prevention and control efforts, the development of new diagnostic testing to facilitate better treatment decisions as well as support development of new antibiotics."

Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. Centers for Disease Control and Prevention has more about antibiotics.

-- Robert Preidt

SOURCE: Society for Healthcare Epidemiology of America, news release, April 3, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. BATTLE researchers identify new biomarkers for EGFR inhibition
2. Pitt-Stanford research suggests aimless proteins crucial to disease
3. New strategic plan for NIH obesity research seeks to curb epidemic
4. Researchers need to engage lesbian, gay, bisexual, and transginder populations in health studies
5. Researchers publish molecular disease model for melanoma
6. Researchers find possible clues to tamoxifen resistance in breast cancer patients
7. UCSF researchers identify promising new treatment for childhood leukemia
8. Research explores link between asthma and smoking
9. Researchers make the leap to whole-cell simulations
10. UT Southwestern research advances fight against kidney cancer
11. Stepchildren relate to stepparents based on perceived benefits, researchers find
Post Your Comments:
Related Image:
Research Warns of Overuse of Powerful Class of Antibiotics
(Date:11/27/2015)... ... November 27, 2015 , ... ... convenient way to dispense prescription medications at home, so he invented the patent-pending ... monitor and dispense prescription medications. In doing so, it could help to prevent ...
(Date:11/27/2015)... ... 2015 , ... MPWH, the No.1 Herpes-only dating community in the world, revealed that over 50% ... More than 3.7 billion people under the age of 50 – or 67% of the ... first global estimates of HSV-1 infection . , "The data shocks us highly!" said ...
(Date:11/27/2015)... ... November 27, 2015 , ... Keeping in mind challenges ... health and wellness consultation, has collaborated with a leading web-based marketplace for extra-curricular ... experienced by parents and bring advice from parenting experts within their reach. As ...
(Date:11/27/2015)... ... November 27, 2015 , ... Indosoft ... announces the incorporation of Asterisk 11 LTS (Long Term Support) into its Q-Suite ... LTS brings Q-Suite 5.10 up-to-date with a version of Asterisk that will receive ...
(Date:11/26/2015)... ... 2015 , ... The Catalent Applied Drug Delivery Institute today ... dose form selection in early phase drug development. The first of these is ... together the UK’s emerging life sciences companies, corporate partners, and investors, at Milton ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 ... "Self Administration of High Viscosity Drugs" ... ) has announced the addition of the ... to their offering. --> Research and ... of the "Self Administration of High Viscosity ...
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... announced the addition of the  "2016 ... the European Cell Surface Marker Testing ... Opportunities"  report to their offering.  ... the addition of the  "2016 Future ...
(Date:11/25/2015)... 25, 2015  Amgen (NASDAQ: AMGN ) today ... with the United States (U.S.) ... biosimilar candidate to Humira ® (adalimumab). Amgen believes ... to the FDA and represents Amgen,s first BLA submission ... Harper , M.D., executive vice president of Research and ...
Breaking Medicine Technology: