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Research Validates Safety of Dawn AC Anticoagulation Management Software
Date:3/24/2009

A respected medical journal recently cited Dawn AC anticoagulation management software as a safe and effective way to provide dosage for patients. The scientific article, published in Thrombosis and Haemostasis, also revealed other significant findings related to the widely-used Dawn AC warfarin software.

Cumbria, England -- Dawn AC's computer-dosage program has proven to be "...as safe clinically for patients as manual dosage by experienced medical staff," according to an article in a recent issue of Thrombosis and Haemostasis (Thromb Haemost 2009; 101:487-494). Led by Professor Leon Poller of the University of Manchester, UK, the scholarly report was authored by a group of eminent thrombosis physicians mainly in Europe and around the world.

The report referenced a large international clinical trial of the Dawn AC computer-assisted oral anticoagulant dosage program. The five-year study involved 2631 patients who were randomized to either manual or computer-assisted dosage in 13 centers around the world.

The Dawn AC program provided dosage for a variety of drugs, including warfarin, nicoumalone (Acenocoumarol) and phenprocoumon. The results were impressive:
·   Clinical events of bleeding and thrombosis were almost identical.
·   Therapeutic INR control improved from 63.4 percent with manual dosage to 66.8 percent with Dawn AC. (These results are particularly significant given that 2,099 or 80 percent of the patients were new to anticoagulation.) This difference between the two legs of the trial was statistically highly significant in terms of INR control.

"The results should reassure hospitals and community clinics that the Dawn AC program is safe and facilitate greater and longer provision of warfarin in treatment where required," the article stated.

Dawn AC's favorable assessment is sign
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