Navigation Links
Research Takes Aim at Pancreatic Cancer
Date:4/18/2009

Discovery and testing in mice may lead to better detection and treatment

SATURDAY, April 18 (HealthDay News) -- An active receptor found in certain pancreatic cancers might offer hope for treatment of the often fatal disease.

A third of human pancreatic cancers looked at by Johns Hopkins University researchers contained a malfunctioning phosophorylated epidermal growth factor receptor (pEGFR), which previous studies had noted as being active in some lung cancers. When mice with this type of pancreatic cancer were given erlotinib, an EGFR-inhibitor drug approved for lung cancer treatment, the pancreatic tumors shrank, according to a news release from Experimental Biology 2009, a program of the American Society for Investigative Pathology.

Hopkins pathologist Dr. Akhilesh Pandey, who made the discovery, was expected to present the findings Saturday in New Orleans at the conference.

Although epidermal growth factor inhibitors had previously been tested as a pancreatic cancer treatment, Pandey and his team re-examined the studies and found that only one of 12 cancer samples tested contained the active pEGFR receptor.

The finding could lead to a biomarker detection tool for pancreatic cancer as well as a new treatment for these types of pancreatic cancers, Pandey said in the news release. His team is now reviewing scientific literature to compile a list of the proteins and genes known to be overexpressed in pancreatic cancers that should be considered future treatment targets.

More information

The American Cancer Society has more about pancreatic cancer.



-- Kevin McKeever



SOURCE: Federation of American Societies for Experimental Biology, news release, April
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Research Takes Aim at Pancreatic Cancer
(Date:10/29/2014)... certain prostate cancer medications are linked with an increased ... congestive heart failure or prior heart attacks. Published in ... and patients weigh the benefits and risks of the ... levels of male hormones in the body to prevent ... treatment for prostate cancer. Despite its anticancer effects, ADT ...
(Date:10/28/2014)... that aims to make personalized medicine a reality for ... across British Columbia. , The "Genomics for Precision Drug ... of its kind in North America. The project is ... (BCPhA), with the research component led by a team ... Sciences (UBC). It will position the pharmacist as the ...
(Date:10/28/2014)... Uppsala University demonstrate that elderly men with self-reported ... Alzheimer,s disease than men without self-reported sleep disturbances. ... Alzheimer,s & Dementia . , The researchers ... 50 year old, between the years 1970 and ... self-reported sleep disturbances were linked to an increased ...
(Date:10/27/2014)... from Massachusetts General Hospital (MGH) investigators has identified ... activity of a key brain region in patients ... a mechanism of action behind one of the ... therapy. They also found evidence that pretreatment ... which patients are likely to respond to that ...
(Date:10/27/2014)... adopt a new therapy by watching others use it, ... , New technology is like an influential colleague -- ... reminded every five to seven days , CHICAGO ... when they are persuaded to do so by an influential ... adopting innovations also have relevance for business, education and research. ...
Breaking Medicine News(10 mins):Health News:Prostate cancer medications linked with increased risk of heart-related deaths in men with cardiovascular problems 2Health News:Genomics helps pharmacists target the right drugs for the right patient 2Health News:PET scans reveal how psychodynamic therapy for depression may change brain function 2Health News:PET scans reveal how psychodynamic therapy for depression may change brain function 3Health News:Persuading doctors to quickly adopt new treatments 2Health News:Persuading doctors to quickly adopt new treatments 3
... recent study accepted for publication in The Endocrine Society,s ... found that postmenopausal women who smoke have higher androgen ... levels being highest in heavy smokers. Previous studies ... are potential risk factors for breast and endometrial cancer ...
... FOR AUG. 31, 2011, ARLINGTON, Va.] Immunizations, including ... protect children from life-threatening pneumonia, according to new guidelines ... Infectious Diseases Society of America (IDSA)., The guidelines, which ... (CAP) in infants and children, place preventing bacterial pneumonia ...
... Research in Marketing Science by Professor Kamel Jedidi, ... Business School; Professor Oded Netzer, Philip H. Geier ... Professor Ricardo Montoya, Department of Industrial Engineering, University ... can maximize the return on marketing investments ...
... Aug. 30 (HealthDay News) -- Nearly one in 10 women in ... new study finds, and they could face a slightly higher risk ... doesn,t prove that so-called "child marriage" causes the increased risk of ... September issue of the journal Pediatrics . Still, the ...
... HealthDay Reporter , TUESDAY, Aug. 30 (HealthDay ... panel began a two-day meeting Tuesday on silicone breast ... post-approval safety studies. After being banned for 14 ... silicone gel-filled breast implants for breast reconstructive surgery and ...
... More and more, patients show up to appointments with hypertension ... products that they hope will help lower their blood pressure. ... products will do any good, or if they will cause ... shift where an increasing number of people want to avoid ...
Cached Medicine News:Health News:Smoking after menopause may increase sex hormone levels 2Health News:IDSA/PIDS announce guidelines for treating pneumonia in children 2Health News:IDSA/PIDS announce guidelines for treating pneumonia in children 3Health News:IDSA/PIDS announce guidelines for treating pneumonia in children 4Health News:Research identifies marketing mix strategy for pharmaceutical firms 2Health News:Women Married Before Age 18 at Higher Risk of Mental Woes: Study 2Health News:Women Married Before Age 18 at Higher Risk of Mental Woes: Study 3Health News:FDA Focuses on Silicone Breast Implant Safety Studies 2Health News:FDA Focuses on Silicone Breast Implant Safety Studies 3Health News:Beyond pills: Cardiologists examine alternatives to halt high blood pressure 2Health News:Beyond pills: Cardiologists examine alternatives to halt high blood pressure 3
(Date:10/30/2014)...  BioMed Realty Trust, Inc. (NYSE: ... on life sciences, today announced financial results for ... Third Quarter 2014 Highlights Financial and Operating ... during the quarter representing approximately 657,700 square feet, ... third quarter of approximately 219,700 square feet; and ...
(Date:10/27/2014)... Research and Markets has announced the ... report to their offering. H1N1 influenza (zoonotic) ... of the swine H1N1 virus, known as H1N1v virus. The ... and lungs. H1N1 virus is an RNA virus belonging to ... such as humans, swine, birds, seals, and horses. Influenza A ...
(Date:10/27/2014)... Research and Markets has announced the addition ... report to their offering. A service ... of tasks that might be simple or complex, time-consuming, ... broad divisions: Professional Robot and Personal/domestic Robot. Professional robots ... such as underwater applications, defense, and security and surveillance ...
Breaking Medicine Technology:BioMed Realty Trust Reports Third Quarter 2014 Financial Results 2BioMed Realty Trust Reports Third Quarter 2014 Financial Results 3BioMed Realty Trust Reports Third Quarter 2014 Financial Results 4BioMed Realty Trust Reports Third Quarter 2014 Financial Results 5BioMed Realty Trust Reports Third Quarter 2014 Financial Results 6BioMed Realty Trust Reports Third Quarter 2014 Financial Results 7BioMed Realty Trust Reports Third Quarter 2014 Financial Results 8BioMed Realty Trust Reports Third Quarter 2014 Financial Results 9BioMed Realty Trust Reports Third Quarter 2014 Financial Results 10BioMed Realty Trust Reports Third Quarter 2014 Financial Results 11BioMed Realty Trust Reports Third Quarter 2014 Financial Results 12BioMed Realty Trust Reports Third Quarter 2014 Financial Results 13BioMed Realty Trust Reports Third Quarter 2014 Financial Results 14BioMed Realty Trust Reports Third Quarter 2014 Financial Results 15BioMed Realty Trust Reports Third Quarter 2014 Financial Results 16BioMed Realty Trust Reports Third Quarter 2014 Financial Results 17BioMed Realty Trust Reports Third Quarter 2014 Financial Results 18BioMed Realty Trust Reports Third Quarter 2014 Financial Results 19BioMed Realty Trust Reports Third Quarter 2014 Financial Results 20BioMed Realty Trust Reports Third Quarter 2014 Financial Results 21Global H1N1 Vaccines Market 2014-2018: Key Vendors are AstraZeneca, GlaxoSmithKline, Novartis and Sanofi Pasteur 2Global H1N1 Vaccines Market 2014-2018: Key Vendors are AstraZeneca, GlaxoSmithKline, Novartis and Sanofi Pasteur 3Global Service Robot Market 2014-2018: Key Vendors are GeckoSystem, Honda Motor, iRobot and Toyota Motor 2Global Service Robot Market 2014-2018: Key Vendors are GeckoSystem, Honda Motor, iRobot and Toyota Motor 3
... N.C. , April 22 The reporting of ... pharmaceutical industry and its importance is clear as the U.S. ... for adverse events. Yet when it comes to gray areas ... A Best Practices, LLC post-marketing surveillance study found that 50 ...
... /PRNewswire-Asia-FirstCall/ -- Lotus Pharmaceuticals,Inc. (OTC Bulletin Board: LTUS) ("Lotus" or the "Company"), a growing,developer, ... (the "PRC"), today reported it will exhibit at the 63rd,PHARMCHINA. , , ... Venue: International Convention ... , , ...
Cached Medicine Technology:Best Practices, LLC Report on Post-Marketing Surveillance Programs Sheds Light on Gray Areas of Adverse Event Reporting 2Best Practices, LLC Report on Post-Marketing Surveillance Programs Sheds Light on Gray Areas of Adverse Event Reporting 3Lotus Pharmaceuticals to Exhibit at the 63rd PHARMCHINA 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: