Navigation Links
Research Reveals How Down Syndrome Shields Against Cancer
Date:5/20/2009

The findings might someday lead to better treatments, experts say

WEDNESDAY, May 20 (HealthDay News) -- A pair of genes may explain why people with Down syndrome are largely spared from many types of cancer, Boston researchers report.

The same genetic mechanism could be a potent target for new anti-cancer therapies, said the scientists, who published their findings online May 20 in Nature.

The pressing question now becomes, when will this happen? Or will it happen at all?

"Most universities around the country are very good at finding targets for intervention in cancer and this study suggests that these two genes, if they were overexpressed in a tumor, could shut down the tumor blood vessels," explained Dr. Arthur E. Frankel, holder of the Tula Lee Stone Chair in Cancer Research at the Texas A&M Health Science Center College of Medicine.

"The problem is that's not such a trivial thing to do," added Frankel, who is also director of the Cancer Research Institute and of hematology/oncology with Scott & White. "The observation is true, but it's not immediately obvious to me that it's going to help anyone in the short term."

Individuals with Down syndrome, the most common genetic cause of mental retardation, carry an extra copy of chromosome 21 and, therefore, extra copies of each of the 231 genes found on that chromosome.

And while people with Down syndrome have an increased risk of developing certain types of leukemia compared to the general population, they have just 10 percent the risk of dying from many common solid-tumor cancers, including breast, brain, pancreas, lung and colon cancers.

The phenomenon has long been a scientific riddle.

"In the 1950s at Harvard Medical School, one of the exam questions was, 'Why don't people with Down Syndrome get cancer?' The answer then was because they don't live long enough," said study senior author Sandra Ryeo
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. PIPC Supports New Comparative Effectiveness Research (CER) Bill
2. CSI: Mayo Clinic Researchers Find Television Shows Inaccurately Portray Violent Crime
3. Prestigious award for outstanding primary-care researcher
4. University of Haifa research team awarded European Union research grant
5. Peter MacCallum Cancer Centre Expands Cancer Research Efforts with Automation Tool from Caliper Life Sciences
6. Research reveals molecular pathway behind invasive prostate cancers
7. Mayo Clinic Researchers Say Triple Drug Combination is Promising Option to Treat Metastatic HER2+ Breast Cancer
8. Two Targeted Therapies Likely Better Than One in Patients with Aggressive Lymphoma, Mayo Clinic Researchers Say
9. Mayo Clinic Researchers Say Agent Provides Treatment Option for Women with Hot Flashes
10. Drug That Targets Vasculature Growth Attacks Aggressive Thyroid Cancer, Mayo Clinic Researchers Report
11. $1.5 million awarded for palliative care research to improve care of seriously ill patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Research Reveals How Down Syndrome Shields Against Cancer
(Date:8/30/2015)... ... August 31, 2015 , ... Avid collector Andrew Hawley ... Doors Shrine Auditorium concert posters. This hand colored artwork is one of the most ... Los Angles. Hawley states, "When the doors played the Shrine, the band was ...
(Date:8/30/2015)... ... August 31, 2015 , ... ChopChop Kids, the nonprofit publisher ... recently elected two new officers to serve on the organization’s Board of Directors ... and teaching kids to cook real food with their families and help continue ...
(Date:8/30/2015)... ... August 30, 2015 , ... Scientists in France say asbestos exposure ... of digestive cancers. Surviving Mesothelioma has just posted an article on the new research. ... Caen measured the cancer incidence among 2,024 French asbestos plant workers from 1978 to ...
(Date:8/30/2015)... ... August 30, 2015 , ... Nutritional Products International ( ... to Executive Assistant to CEO Mitch Gould for Nutritional Products International. Through ... goals. Kathleen graduated from Florida State University with a Bachelor of Science ...
(Date:8/29/2015)... ... August 29, 2015 , ... On Saturday, September 19, 2015, Diane ... Foundation (Meso Foundation) will present an educational program titled “Asbestos and Your Health.” ... through 9:30 PM (doors open at 6:45pm) at Calvary United Methodist Church, 16 E ...
Breaking Medicine News(10 mins):Health News:ChopChop Kids Appoints New Chair and Vice-Chair to Board of Directors 2Health News:ChopChop Kids Appoints New Chair and Vice-Chair to Board of Directors 3Health News:Researchers Say Mesothelioma Not the Only Cancer Linked with Asbestos Exposure, According to Surviving Mesothelioma 2Health News:NPI Appoints New Executive Assistant To CEO 2Health News:Mesothelioma Applied Research Foundation to Hold Educational Class About Asbestos and Mesothelioma Prevention 2
... likely woman was first infected with dangerous germ, , , WEDNESDAY, ... their food and more with their pets, but one thing ... is a drug-resistant staph infection. , However, according to a ... England Journal of Medicine , a German family appears to ...
... Public Understanding of a,21st Century Epidemic, ... of the,population, experts warn that Alzheimer,s disease ... and unsustainable burdens in,terms of health care ... lost to a devastating disease., (Photo: ...
... 2008, LANCASTER, Pa., March 12 Herley Industries,Inc. ... the second quarter,ended February 3, 2008., Net sales ... $34.7 million. Net loss for the period was approximately ... Company,s Chairman and CEO, will host a conference call,on ...
... 3 and Turmeric ... Supplement, LEXINGTON, ... the latest addition to their family of joint,relief products, which can be ... formula containing Omega 3 and,Turmeric for double strength joint relief., Over ...
... Caregivers were stressed, ate poorly, study found , , WEDNESDAY, March ... serious heart problem may raise your own risk of cardiac ... than 500 family members and others caring for a heart ... of the time were more likely to show psychological strain ...
... novel aerosol version of the most common tuberculosis ... an oral mist, offers significantly better protection against ... dose of the traditional injected vaccine, researchers report ... Academy of Sciences. , The aerosol vaccine -- ...
Cached Medicine News:Health News:Woman and Cat Shared 'Super Bug' 2Health News:Woman and Cat Shared 'Super Bug' 3Health News:New Tools Boost Alzheimer's Awareness 2Health News:New Tools Boost Alzheimer's Awareness 3Health News:Herley Reports Second Quarter Results 2Health News:Herley Reports Second Quarter Results 3Health News:Herley Reports Second Quarter Results 4Health News:Herley Reports Second Quarter Results 5Health News:Herley Reports Second Quarter Results 6Health News:Herley Reports Second Quarter Results 7Health News:Herley Reports Second Quarter Results 8Health News:Herley Reports Second Quarter Results 9Health News:Herley Reports Second Quarter Results 10Health News:The Makers of Conquer HA(TM) Launch All-Natural Double Strength Anti- Inflammatory Formula 2Health News:Caring for Heart Patients Can Strain Hearts 2Health News:Caring for Heart Patients Can Strain Hearts 3Health News:Inhaled tuberculosis vaccine more effective than traditional shot 2
(Date:8/28/2015)... and LONDON , August 28, ... approach seamlessly connects people, ... improving outcomes and the cost ... PHG AEX: PHIA) today announced its presence at  ESC ... cardiology solutions, including Heart Model A.I. , EchoNavigator and IntelliSpace ...
(Date:8/27/2015)... CUPERTINO, Calif. , Aug. 27, 2015 ... management is scheduled to present at three upcoming healthcare ... , President and CEO, will present at the Rodman ... 10:00 a.m. Eastern time. The conference is being held ... York City . A live audio webcast of ...
(Date:8/27/2015)... Aug. 27, 2015  Eli Lilly and Company (NYSE: ... Healthcare Conference on Thursday, September 17, 2015. Sue ... Lilly Oncology and Richard Gaynor , M.D., senior ... Lilly Oncology, will participate in a fireside chat at ... live audio webcast will be available on the "Webcasts ...
Breaking Medicine Technology:Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 2Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 3Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 4DURECT to Participate in Upcoming Healthcare Conferences 2Lilly to Participate in Morgan Stanley Global Healthcare Conference 2
... Parkinson,s Disease, ... Decision Resources, WALTHAM, Mass., Aug. 13 Decision ... focusing on pharmaceutical and,healthcare issues, finds that 61 percent ... drug treatment in the first year of,diagnosis. According to ...
... VIENNA, Va., Aug. 14 CEL-SCI CORPORATION,(Amex: ... an agreement with a,biomedical real estate group under which ... for its cancer drug Multikine(R). The,financial value of this ... located near Baltimore, Maryland. Once fully built out to ...
Cached Medicine Technology:Sixty-One Percent of Newly Diagnosed Parkinson's Disease Patients Do Not Receive Any Drug Treatment in the First Year of Diagnosis 2Sixty-One Percent of Newly Diagnosed Parkinson's Disease Patients Do Not Receive Any Drug Treatment in the First Year of Diagnosis 3CEL-SCI Secures Manufacturing Facility for Multikine Cancer Drug 2CEL-SCI Secures Manufacturing Facility for Multikine Cancer Drug 3CEL-SCI Secures Manufacturing Facility for Multikine Cancer Drug 4
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
... a monopolar cautery connector extending from the ... used for electrosurgery when properly attached to ... ,Ethicon Endo-Surgery provides disposable handheld instruments ... Our handheld instruments come in 5mm and ...
... The Featured Products ... at Mediflex and are ... modular in regular or ... come equipped with insulation, ...
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
Medicine Products: