Navigation Links
Research Reveals How Breast Cancer Rearranges Genome
Date:12/24/2009

Disease plays havoc with DNA sequence, study finds

THURSDAY, Dec. 24 (HealthDay News) -- An analysis of breast cancer genomes has provided insight into how the human genome is rearranged when the disease strikes, researchers report.

"We have looked at the level of the DNA sequence at just how splintered and reorganized the genome is in many breast cancers. We were, frankly, astounded at the number and complexity of rearrangements in some cancers," Mike Stratton of the Wellcome Trust Sanger Institute in Cambridge, U.K., said in a news release from the institute.

"Just as important, the genomes were different from each other, with multiple distinctive patterns of rearrangement observed, supporting the view that breast cancer is not one, but several diseases," Stratton added.

According to the researchers, who looked at 24 breast cancer samples, the study findings will help doctors do a better job of classifying tumors, which will improve the diagnosis and treatment of breast cancer.

"It looks as though some breast cancers have a defect in the machinery that maintains and repairs DNA, and this defect is resulting in large numbers of these abnormalities," said the institute's Dr. Andy Futreal, in the news release. "At the moment, we do not know what the defect is or the abnormal gene underlying it, but we are seeing the result of its malfunction in the hideously untidy state of these genomes. Identifying the underlying mutated cause will be central to working out how some breast cancers develop."

The study findings are published online Dec. 23 in the journal Nature.

More information

The U.S. National Cancer Institute has more about breast cancer.



-- Randy Dotinga



SOURCE: Wellcome Trust Sanger Institute, news release, Dec. 23, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Researchers find new patterns in H1N1 deaths
2. Hard to treat Diseases (HTDS) To Sell Its MindUp BioResearch Division
3. Pot and pop: New research finds stronger link between music and marijuana use among teens
4. National MS Society Continues to Propel Research Forward to End MS - Launches 2010 With Call for Research Grants to Pursue CCSVI Leads
5. Lung Cancer Foundation of America Gives the Gift of Life This Holiday Season: Announces Inaugural $125,000 Scientific Research Grant
6. Researchers discover gene therapy to prevent progression of emphysema
7. Orameds Dr Roy Eldor was Chosen to Lecture at the First International Conference Held by the Bildirici Center for Diabetes Care Research in Israel.
8. Exposing the Double Standard of the Forgotten Cancer: Biggest Cancer Killer for Women and Men, Lung Cancer, Receives Least Research Funds
9. Lung Cancer Alliance Hails New Federal Funding for Lung Cancer Research
10. IBS Treatment Center Calls on McCain to Support IBS Research
11. Researchers at the John Theurer Cancer Center Present Cutting-Edge Research Results at this Years American Society of Hematology Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2017)... ... 2017 , ... After months of negotiations, FaceCradle USA is proud to announce the debut of ... , “Introducing our product on QVC is something we all worked hard to achieve for ... more than 90 million homes in the United States,” said FaceCradle USA President Dylan Doherty. ...
(Date:6/20/2017)... ... 20, 2017 , ... Hayes, Inc., a leading provider of ... “ 5 Questions to Ask Before Entering the Maze of Genetic Testing .” ... (GTE) team, the book explores the various types of the more than 65,000 ...
(Date:6/20/2017)... , ... June 20, 2017 , ... Kenneth Mayer, MD, ... Society (JIAS). , Dr. Mayer, who joined the JIAS Editorial Board in 2016, ... founding Medical Research Director of Fenway Health and Co-Chair of The Fenway ...
(Date:6/20/2017)... ... June 20, 2017 , ... HOUSTON – Brazos Towers at Bayou ... host of new options for today’s modern senior. Brazos Towers at Bayou Manor has ... they love while offering them the services to support that lifestyle both now and ...
(Date:6/20/2017)... SAN DIEGO, California (PRWEB) , ... June 20, ... ... modern product documentation and help content solutions for the enterprise, is proud to ... web properties, including CRM, e-commerce, ticketing systems, company websites, and more to provide ...
Breaking Medicine News(10 mins):
(Date:6/14/2017)... Calif. , June 14, 2017 The ... the City of Fremont and ... of the bio-pharma industry in California ... technology, enabling executive networking, and fostering workforce development. The ... development and growth of start-ups, as well as small ...
(Date:6/12/2017)... , June 12, 2017 Kineta, Inc., a ... announced Kineta Vice President of R&D and Head ... the Pandemic Preparedness for the Northwest and Beyond ... held on June 14, 2017 from 8:30-10:30 AM PDT at ... Dr. Bedard will be joined by ...
(Date:6/9/2017)... AirXpanders, Inc. (ASX: AXP) (AirXpanders or Company), ... sale and distribution of the AeroForm® Tissue Expander System, ... commercial roll-out in the United States ... hundred (100) medical institutions and health systems, located throughout ... alternative for women who choose reconstructive surgery following a ...
Breaking Medicine Technology: