Navigation Links
Research Highlights New Approaches to Management of Blood Clotting and Bleeding Disorders
Date:12/8/2007

es undertaken in patients with chronic ITP, as platelets targeted for destruction will often meet their fate in the spleen. Splenectomy is said to be successful in 60 percent of cases although it is less successful in older people. AMG 531 is a novel "peptibody" that acts by stimulating platelet production at the thrombopoietin receptor. Thrombopoietin is a hormone that promotes platelet production by the bone marrow. In this study, subcutaneous AMG 531 or placebo was administered weekly for 24 weeks at a starting dose of 1µg/kg, and adjusted to maintain a target platelet count of 50-200x109/L in the 63 enrolled splenectomized patients with ITP. The results indicated that AMG 531 was well tolerated and effectively increased and sustained platelet counts in patients. AMG 531-treated patients required less frequent rescue medications (medications needed in an emergency to re-stabilize platelet counts and prevent or treat bleeding) in comparison with those receiving the placebo, and were able to reduce their use of concurrent ITP therapies.

-- RECORD1 is the first pivotal trial to demonstrate the efficacy and safety of a fixed, unmonitored dose of an oral, direct Factor Xa inhibitor -- rivaroxaban -- for extended prevention of blood clotting after a total hip replacement [Abstract #6]

Bengt I. Eriksson, MD, PhD, Ortopedkliniken, Sahlgrenska University Hospital/Ostra, Goteborg, Sweden

This multinational, randomized, double-blind, double-dummy phase III trial studied the efficacy and safety of oral rivaroxaban in comparison to subcutaneous enoxaparin to prevent blood clotting (a process known as thromboprophylaxis) for five weeks in patients undergoing a total hip replacement (THA). Thromboprophylaxis is recommended for at least 10 days and for up to four to five weeks after total hip replacement in order to avoid the formation of a thrombembolism, or a clot in a blood vessel that breaks loose and is carried by the blood stream to plug another
'/>"/>

SOURCE American Society of Hematology
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... Randy Dotinga HealthDay Reporter ... genetic tests are developed that spot increased risks for certain ... proactive about getting screened. But a new study suggests ... behavior: People who found out their genes doubled their risk ... average risk to get screened. "It didn,t make any ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 On Saturday, October ... its fourth annual family health and fitness fair ¡Vive tu ... physical activity and good nutrition for better health and wellness ... which is free and open to the public, will be ... Brownsville, from 9:00 am to 1:00 pm. , “¡Vive ...
(Date:10/22/2014)... 2014 Isabel Healthcare will ... Professions (ASAHP) Conference on October 22-24 in Las Vegas, ... in a panel discussion on Technology in Health Professions ... provides a diagnostic decision support tool and clinical education ... of students and clinical learners. The Isabel tools help ...
(Date:10/22/2014)... TUESDAY, Oct. 21, 2014 (HealthDay News) -- The ... passengers arriving from Ebola-affected nations of West Africa ... screen them for infection with the virus. ... Jeh Johnson noted that 94 percent of air ... land at one of these five airports -- ...
(Date:10/22/2014)... California (PRWEB) October 22, 2014 Hay House ... Move Beyond Addiction and Upgrade Your Life (Paperback; $10.82) written ... of Yoga & Recovery. This book is meant to ... in a life of recovery. , Recovery 2.0 is ... 12 Steps; Recovery 2.0 is a guide for what comes ...
Breaking Medicine News(10 mins):Health News:Knowing Genetic Risk for Cancer May Not Change Behavior 2Health News:Brownsville Community Health Center Presents Fourth Annual ¡Vive Tu Vida! Get Up! Get Moving!® Event 2Health News:Brownsville Community Health Center Presents Fourth Annual ¡Vive Tu Vida! Get Up! Get Moving!® Event 3Health News:Brownsville Community Health Center Presents Fourth Annual ¡Vive Tu Vida! Get Up! Get Moving!® Event 4Health News:Isabel Healthcare to Participate in The Association of Schools of Allied Health Professions (ASAHP) 2014 Conference 2Health News:Passengers From Ebola-Affected Countries Must Land at Designated U.S. Airports 2Health News:Passengers From Ebola-Affected Countries Must Land at Designated U.S. Airports 3Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 3
... ... your brand, advertising campaign, competitors or product innovations. , ... (PRWEB) April 6, 2010 -- Six Degrees has ... affordable way to gather insights needed to optimize marketing strategies, increase advertising effectiveness, gather ...
... is weak , TUESDAY, April 6 (HealthDay News) -- A ... in fruits and vegetables helps protect against cancer. , U.S. ... in 10 European countries and found only a weak association ... risk. , The study did find that heavy drinkers who ...
... ARBOR, Mich.---The proportion of older middle-aged Americans who report ... 2007, in contrast to the disability decline that has ... to a new study by the RAND Corporation and ... in the proportion of Americans aged 50 to 64 ...
... support care between office visits, boost efficiency and convenience, ... the April Health Affairs suggests how to ... patients how they like it and what they want. ... health information technology they use is meeting their needs ...
... ... Builders of the Dawn reveals a new world growing all around us and the keys to ... ... planet in 2010 may make some people want to go into hiding. But the authors of ...
... 5, 2010 The Clinical Practice Model Resource Center ... practice guidelines for healthcare, today launched its first Web-based ... online edition of its award-winning guidelines supports new and ... collaboration with a model that helps improve practice at ...
Cached Medicine News:Health News:Fruits, Veggies Have Modest Effect on Cancer Risk 2Health News:Middle-aged Americans report more mobility-related disabilities 2Health News:Middle-aged Americans report more mobility-related disabilities 3Health News:Want better health information technology? Ask patients how they want it 2Health News:The Practical Visionary Offers Eight Keys to Surviving and Thriving in the 21st Century, 2Health News:The Practical Visionary Offers Eight Keys to Surviving and Thriving in the 21st Century, 3Health News:The Practical Visionary Offers Eight Keys to Surviving and Thriving in the 21st Century, 4Health News:The Practical Visionary Offers Eight Keys to Surviving and Thriving in the 21st Century, 5Health News:The CPM Resource Center launches Web-based clinical practice guidelines 2
(Date:10/22/2014)...  Quest Diagnostics (NYSE: DGX ), the ... that its Board of Directors has elected Jeffrey M. ... 1, 2014. Including Dr. Leiden, the Board has 11 ... and CEO of Vertex Pharmaceuticals.   Dr. Leiden has ... in the pharmaceutical and biotechnology industries as well as ...
(Date:10/22/2014)... Calif. , Oct 22, 2014 Antigen ... Irvine, California , announced the receipt of ... Business Innovation Research award (SBIR) from the National Institute of Dental ... fund the development of a Pan-HIV Protein Microarray Chip, ... HIV-1 and HIV-2 subtypes and aid in the development ...
(Date:10/22/2014)... , Oct. 22, 2014   Reproductive Medicine ... leader in the field of infertility, presents new ... embryonic screening. The research abstract, released during the ... Medicine (ASRM) meeting in Honolulu, Hawaii ... single gene defect (SGD) pre-implantation genetic diagnosis (PGD). ...
Breaking Medicine Technology:Quest Diagnostics Adds Jeffrey M. Leiden, M.D., Ph.D., to Board of Directors 2Quest Diagnostics Adds Jeffrey M. Leiden, M.D., Ph.D., to Board of Directors 3Biomarker Discovery Company, Antigen Discovery Inc., Awarded an NIH Phase I Small Business Innovation Research Grant to Develop a Pan-HIV Protein Microarray Chip 2New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 2New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 3
... patented ratchet design provides fingertip ratchet disengagement ... I Instrument program offers state-of-the-art quality in ... maintaining strength and durability. Low profile cutting ... joint spaces. Series I instruments are available ...
Leg holder for arthroscopy....
Irrigation pump for arthroscopy....
The 300 watt Xenon light source will provide intense illumination necessary for demanding, advanced endoscopic procedures....
Medicine Products: