Navigation Links
Research Finds Use of Volpara Objective Breast Density Software from Matakina Helps Overcome the Limitations of Mammography for Women with Dense Breasts
Date:3/4/2013

VIENNA, Austria (PRWEB) March 04, 2013

Objective breast density measurement and its impact on breast imaging are among the key abstracts being presented here at the European Congress of Radiology (ECR) meeting, March 7-11, 2013. According to Matakina International, six abstracts highlight the use of Volpara objective breast density measurement software to help overcome the limitations of mammography for women with dense breasts.

Volpara was also recently selected for use in the European Union (EU) collaborative Adapting Breast Cancer Screening Strategy Using Personalised Risk Estimation (ASSURE) research project. Matakina will showcase its role in the ASSURE project as well as the use of Volpara in a number of large clinical trials and national breast cancer screening programs across Europe. (ECR 2013 Booth: Expo E 560).

In her Educational Exhibit (C-1033), titled “This is what volumetric breast density is”         Dr. Gisella Gennaro illustrates how volumetric breast density can be measured on digital mammograms and describes potential clinical applications. Showing quantitative breast density results for more than 500 women from Padua, Italy, Dr. Gennaro concludes that volumetric breast density has potential to become helpful in tailoring patient workups, in order to overcome limitations in mammography for highly dense breasts.

Cleared by the FDA, HealthCanada, the TGA and CE-marked, Volpara is in use at sites across the globe helping radiologists assess breast density more objectively and helping them better consider who might benefit from additional screening. Volpara is a reliable tool which generates objective, automatic measurement of volumetric breast density and a FDA cleared BI-RADS breast density category. Volpara supports most of the major digital mammography systems, can be displayed on digital mammography and PACS workstations and be integrated into mammography reporting systems.

Breast density has been known to increase the risk of breast cancer and recent studies suggest that abnormal changes in breast density over time could also be associated with increased risk. Temporal changes may also aid in evaluating the impact of age and menopause on the breast. However, reader variability and differences in the “For Presentation” mammographic images generated on different vendor x-ray machines, make it difficult to judge breast density change. In the presentation “Assessing breast density changes over time,” (C-1770), Dr. Ralph Highnam, CEO of Matakina International and a co-author, introduces a novel objective method for transforming sequential mammograms into temporal density movies to address some of these issues. Results demonstrate high levels of agreement between sequential images and the use of optimized density maps help standardize mammographic images from different manufacturers to facilitate better judgement of temporal changes. “Breast density is one of the few modifiable breast cancer risk factors and we are encouraged that these results show strong potential for Volpara to accurately track changes in breast density over time,” said Dr. Highnam.

In a similar line of research, Professor Nico Karssemeijer has been testing the temporal stability of Volpara in the exhibit, “Temporal stability of fully automatic volumetric breast density estimation in a large screening population” (C-1953). They ran Volpara over 42,414 temporal pairs of mammograms and looked to see how often Volpara declared the woman to have moved from being a fatty breast (BIRADS 1,2) to a dense breast (BIRADS 3,4). Researchers noted that in a recent study of human observers some 7.1% of the time such a biologically implausible shift was noted, whilst for Volpara it was only 4.1% indicating that Volpara is far more robust at judging temporal change.

Another study, “BI-RADS breast density classification – an international standard?” (C-1762) will review comparisons between volumetric and visual assessment around the world. According to Dr. Highnam, results of the study suggest that there might be systematic bias in people’s interpretations of BI-RADS. “For example, if you see very dense breasts all the time you probably judge BI-RADS breast density lower than if you see fatty breasts all the time. In addition, with US radiologists judging the same set significantly higher than European and Asian radiologists, there is a clear need for a more standardized approach to breast density assessments which will help in interpreting and comparing breast cancer risk studies that are carried out internationally.”

Professor Kwan Ng from University of Malaya is presenting on, “Are volumetric breast density measurements robust enough for routine clinical use?” (C-1787). Prof Ng builds on earlier work which looked at volumetric breast density implementations which used absolute physics and were too susceptible to errors in the physics data. Prof Ng has exhaustively tested Volpara and concludes the Volpara software is robust and ready for routine clinical use. Based on these results, Prof Ng is considering breast screening in Malaysia and his presentation at ECR will show that Chinese-Malay have a significantly higher volumetric breast density than either Malay-Malays and Indian-Malays, and thus might warrant different screening procedures.

For information regarding other research being presented regarding breast density at the ECR meeting, note that in Breast SS1702, there are a range of talks looking at the role of tomosynthesis by breast density including talks from Spain and Italy.

About Matakina
Founded to enable radiologists to give women the most accurate information possible regarding their breast health, Matakina International, Limited is the wholly owned sales and marketing arm of Matakina Technology Limited of New Zealand. Volpara’s founders and Board of Directors includes John Hood, PhD, former Vice Chancellor of the University of Oxford, UK; Ralph Highnam, PhD, former CEO of Mirada Solutions, one of the University of Oxford’s most successful spin-outs of recent times and co-author of the seminal book Mammographic Image Analysis; and Professor Sir Michael Brady, a serial entrepreneur who recently retired from the University of Oxford where he was Professor of Information Technology for 25 years.

# # #

Media Contact:
Chris K. Joseph
510/435-4031
chris(at)ckjcomm(dot)com

Read the full story at http://www.prweb.com/releases/2013/3/prweb10480552.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. UCLA Brain Injury Research Center gets NCAA funding for research on sports concussions
2. NIH awards $20 million over 5 years to train next generation of global health researchers
3. Researchers develop a new cell and animal model of inflammatory breast cancer
4. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
5. Sexually abused boys at risk for more unsafe sex: UBC research
6. Researchers Find Gene Mutations That May Be a Key to Autism
7. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
8. Researchers find evidence of banned antibiotics in poultry products
9. Presidential keynote address and new research highlights from the American Society of Pediatric Otolaryngology meeting
10. Scientific session and new research highlights
11. NJ stroke researchers report advances in spatial neglect research at AAN Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... (PRWEB) , ... February 26, 2017 , ... ... Parkinson’s disease (PD) in persons with a specific LRRK2 mutation, according to a ... , Previous studies have provided evidence of a link between pesticides and incidence ...
(Date:2/24/2017)... ... February 24, 2017 , ... HealthPostures, expert standing desk ... and advantages built into the home office sit stand solution are bold colors, ... to gain the benefits embedded in the TaskMate Go are available 24/7 through ...
(Date:2/24/2017)... ... February 24, 2017 , ... Only two months after the official release of ... in Cannes (France), XO Private has initiated a second print-run of its lavish luxury ... a metre across when open, weighs in at more than six kilos, retails at ...
(Date:2/24/2017)... ... ... An in-depth computational analysis of genetic variants implicated in both schizophrenia and ... may explain why susceptibility to one of the disorders could place individuals at lower ... the journal npj Schizophrenia. , “There is a wealth of genomic data on ...
(Date:2/24/2017)... ... ... Smart Machine Age is here, and it’s disrupting everything. Not only could it drive ... United States may be taken over by technology in the next five to fifteen ... colleagues is drawing to a close. Success will belong to those who can quiet ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... Biophysics Corporation, a global medical device manufacturer based in ... growth in 2016 when compared to the previous year based ... fueled by its AffloVest® sales in the United ... global sales of surgical product lines. Said H. ... 25 th year in delivering high-quality, innovative medical devices ...
(Date:2/27/2017)... (NASDAQ: IPXL ) today announced that it plans to participate ... James and Associates, 38 th Annual Institutional Investors Conference at ... Cowen and Company 37 th Annual ... Boston, MA. Barclays Global Healthcare ... FL. Individuals may listen to the ...
(Date:2/27/2017)... Israel , Feb. 27, 2017 ... of adult stem cell technologies for neurodegenerative diseases, announced ... M.D., Ph.D., FACP, and Arturo O. Araya , ... "Dr. Almenoff and Mr. Araya are talented and ... time for our company," said Chaim Lebovits , ...
Breaking Medicine Technology: