Navigation Links
Research Finds Causal Link Between Ending Drinking, Depression

But giving mice on the wagon an antidepressant restored brain's ability to make new cells

FRIDAY, July 18 (HealthDay News) -- Giving up your few drinks a day may lead to health issues, including depression, a new study says.

"Our research in an animal model establishes a causal link between abstinence from alcohol drinking and depression," study senior author Clyde W. Hodge, a professor of psychiatry and pharmacology in the University of North Carolina School of Medicine, said in a UNC news release. "In mice that voluntarily drank alcohol for 28 days, depression-like behavior was evident 14 days after termination of alcohol drinking. This suggests that people who stop drinking may experience negative mood states days or weeks after the alcohol has cleared their systems."

The research, published online in the journal Neuropsychopharmacology, also found that the mice developed a reduced capacity for the brain to produce new neurons, a process called neurogenesis. This lack of neuron production occurred in the hippocampus, an area critical for learning and memory.

Recent studies have also shown neuron development in the hippocampus may regulate mood, Hodge said.

"Thus, people who drink moderate alcohol socially, or for potential health benefits, may experience negative mood or diminished cognitive abilities due to a loss of the brain's ability to form new neurons," he said.

However, the researchers also found that treating the mice on the wagon for 14 days with an antidepressant prevented the depression and restored the brain's ability to produce new cells.

"Treatment with antidepressant drugs may help people who suffer from both alcoholism and depression by restoring the brain's ability to form new neurons," Hodge said. "Moreover, this research provides an animal model of alcohol-related depression with which we can begin to fully understand the neurobiology underlying co-occurring alcoholism and depression, and thereby develop successful treatment options."

Some scientific evidence has long suggested that moderate drinking may help prevent heart disease, certain types of stroke and some forms of cancer.

More information

The U.S. National Library of Medicine has more about alcohol and health.

-- Kevin McKeever

SOURCE: University of North Carolina School of Medicine, news release, July 8, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Alzheimers Research Brings Progress, Setbacks
2. The Supports Intensity Scale Assessment Can be Used to Build Robust Funding Methods for Developmental Disability Services, New Research Reveals
3. North Carolinas Center For Advanced Medicine & Clinical Research Celebrates Opening of New LKN Medical Spa and Rejuvenation Center
4. New research from Rhode Island Hospital may help predict outcomes for stomach cancer patients
5. Researchers Find Link Between Organ Transplants, Cancer
6. R&D and Regulatory Leaders in the Cosmetics/Personal Care Field Present Latest Industry Research at HBA Global Expo
7. Tufts researchers discover link between DNA palindromes and disease
8. Researchers hone technique to KO pediatric brain tumors
9. Chicago-Based Speaker/Author Concurs with Research Finding of Using Journaling as a Tool to Combat Obesity and Other Health Problems
10. Researchers link Huntingtons disease to overactive immune response in the brain
11. Dartmouth research reveals passive learning imprints on the brain just like active learning
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... A novel class of antimicrobials ... effective in fighting methicillin-resistant Staphylococcus aureus (MRSA), one of the major drug-resistant bacterial ... small molecule analogs that target the functions of SecA, a central part of ...
(Date:11/30/2015)... ... 30, 2015 , ... Using a combination of two blood sugar tests rather ... according to a new study by researchers at the School of Public Health at ... Using Combinations of Blood Glucose Tests ,” published in Frontiers in Public Health, the ...
(Date:11/30/2015)... PA (PRWEB) , ... November 30, 2015 , ... ... to a new study by UPMC and KingMed Diagnostics ... over three years found that consultation with UPMC pathologists resulted in significantly altered ...
(Date:11/30/2015)... ... 30, 2015 , ... The Foundation for Breast and Prostate ... joining forces with the award-winning creator and writer of Downton Abbey Julian Fellowes ... at the Union League of Philadelphia. , The benefit, titled “An Evening ...
(Date:11/30/2015)... , ... November 30, 2015 , ... ... for the last 15 years, announced today that Michigan-based Family Health Center (FHC) ... care for over 45 years, FHC was awarded the largest Affordable Care Act ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Diagnostics, the U.S.-based manufacturer of point-of-care biometric testing devices ... systems, and PTS Detect™ cotinine systems, has announced the ... the company into the mHealth market. ... The technology is a system that interfaces with mobile ... and uses test strip technology already developed by PTS ...
(Date:11/30/2015)... and ST. LOUIS , Nov. ... (NASDAQ: ESRX ) today announced an early renewal ... which began in 1999, will now extend through at ... --> After evaluating pharmacy benefit manager capabilities during ... Express Scripts continues to offer the best health plan ...
(Date:11/30/2015)... 30, 2015   Nuance Communications, Inc. (NASDAQ: ... Support Company (NDSC) today jointly announced a new ... that utilize the American College of Radiology,s (ACR) Imaging ... to comply with current and emerging value-based payment ... --> By combining clinical decision support, radiology reporting ...
Breaking Medicine Technology: