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Research Findings on Nine GlaxoSmithKline Cancer Compounds to be Presented at ASCO 2009
Date:5/11/2009

Data Include First Presentation of Phase III Progression Free Survival Results for Pazopanib in Kidney Cancer

LONDON and PHILADELPHIA, May 11 /PRNewswire/ -- GlaxoSmithKline (GSK) Oncology announced that new clinical data from nine of its oncology molecules will be featured in various presentations at the annual meeting of the American Society of Clinical Oncology (ASCO) in Orlando beginning May 29. The presentations cover GSK Oncology research in solid and blood tumor treatment, supportive care and prevention in an array of difficult to treat tumors including kidney cancer, advanced breast cancer, leukemia and prostate cancer.

The following investigational presentations reflect the broad spectrum of GSK-sponsored studies being presented at this year's ASCO Congress:

Kidney Cancer: New, pivotal Phase III data surrounding the GSK oral, investigational, angiogenesis/VEGF inhibitor, pazopanib. Also, Phase II data on GSK089, a new investigational compound with a MET/VEGFR2 mechanism of action.

  • ORAL PRESENTATION: "A randomized, double-blind Phase III study of pazopanib in treatment naive and cytokine-pretreated patients with advanced renal cell carcinoma (RCC)." Dr. C. Sternberg, San Camillo and Forlanini Hospitals, Italy; Presentation on June 1.
  • "A Phase II study of 2 dosing regimens of GSK 1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in patients (pts) with papillary renal carcinoma (PRC)." Dr. R. Srinivasan, National Cancer Institute; Poster presentation on May 31.

Gastric Cancer: Investigational Phase II study exploring GSK089 in gastric cancer.

  • ORAL PRESENTATION: "Assessment of 2 dosing schedules of GSK1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in metastatic gastric cancer (GC): Interim results of a multicenter phase II study." Dr. M. A. Shah, Memorial-Slo
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SOURCE GlaxoSmithKline
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