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Research: Lupus drugs carry no significant cancer risk for patients
Date:1/24/2013

ugs commonly used to treat SLE including cyclophosphamide, a drug reserved for severe lupus cases and other chronic inflammatory rheumatic diseases.

The results showed that the risk for lymphoma in lupus patients exposed to cyclophosphamide was less than 0.1% per year. In addition, no clear association was observed between lupus disease activity and lymphoma risk.

"People have been wondering for a long time whether the medications were to blame and the results are reassuring, suggesting that most lymphoma cases in SLE are not triggered by drug exposures," says Dr. Bernatsky.

"This is very good news that cancer risk associated with lupus medication is relatively low," said Louise Bergeron, who has been living with lupus for 12 years.

"It reassures me, especially if I need to take more effective immunosuppressive treatments in the coming years."

Future research will focus on the genetic profiles of lupus patients and what impact that can have on the interaction between medication exposure and lymphoma risk in lupus.


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Contact: Julie Robert
julie.robert@muhc.mcgill.ca
514-934-1934 x71381
McGill University Health Centre
Source:Eurekalert

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