Navigation Links
Reproductive Factors May Protect Women from Parkinson's Disease

SEATTLE, Feb. 26 /PRNewswire-USNewswire/ -- A large new study provides evidence that longer exposure to the body's own hormones may protect women from Parkinson's disease. The study was released today and will be presented at the American Academy of Neurology's 61st Annual Meeting in Seattle, April 25 to May 2, 2009.

The study found that women who have more years of fertile lifespan (number of years from first menstruation to menopause) had a lower risk of developing the disease than women with fewer years of fertile lifespan. The fertile lifespan is a marker for the body's own sex hormone levels. In addition, women with four or more pregnancies were at greater risk of developing the disease than women with fewer pregnancies. Separately, the risk of Parkinson's disease was increased in women who had hysterectomies and had also previously taken hormone replacement therapy compared to those who never took hormone therapy, but it was not increased in women who took the hormones but had not had hysterectomies.

"These findings suggest that longer duration of exposure to the body's own (endogenous) hormones may help protect the brain cells that are affected by Parkinson's disease. Further investigation is necessary to explain why women with four or more pregnancies are at increased risk compared with those with fewer pregnancies. This study does not support a role for treatment with hormone therapy in Parkinson's, but there are still many unanswered questions," said study author Rachel Saunders-Pullman, MD, MPH, MS, of Albert Einstein College of Medicine in Bronx, NY, and Beth Israel Medical Center in New York, NY, and a member of the American Academy of Neurology.

For the study, researchers analyzed the records of the Women's Health Initiative Observational Study to determine who developed Parkinson's disease. The study involved about 74,000 women who underwent natural menopause and about 7,800 women who underwent surgical menopause.

Among women with natural menopause, those who had a fertile lifespan of more than 39 years, which is a time associated with higher levels of the body's own sex hormones, had about a 25-percent lower risk of developing the disease than women with a fertile lifespan shorter than 33 years. Researchers also looked at the number of pregnancies, and women who had four or more pregnancies were about 20 percent more likely to develop Parkinson's disease than women who had three or fewer pregnancies.

Women who had menopause from surgery had almost twice the risk of developing the disease if they had previously taken hormone therapy and stopped than if they had never taken hormone therapy. Taking hormones did not have any effect on Parkinson's risk for women who had natural menopause.

Because Parkinson's disease is more common in men than in women, researchers have long hypothesized about the role of hormones in the disease.

The study was supported by the Thomas Hartman Foundation for Parkinson's Research and the National Institutes of Health.

The American Academy of Neurology, an association of more than 21,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as multiple sclerosis, restless legs syndrome, Alzheimer's disease, narcolepsy, and stroke.

For more information about the American Academy of Neurology, visit

The AAN 61st Annual Meeting, the world's largest gathering of neurology professionals, takes place April 25 to May 2, 2009, in Seattle. Visit for more information.

Editor's Note: Study authors are available for interviews. Please contact Jenine Anderson, or Jay Mac Bride,

To access 2009 AAN Annual Meeting abstracts available February 25, 2009, visit

Late-breaking abstracts will be featured in press release at the 2009 AAN Annual Meeting in Seattle.

Media Contacts:

Jenine Anderson, (651) 695-2789,

Jay Mac Bride, (651) 695-2795,

SOURCE American Academy of Neurology
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Local Infertility Specialist, Dr. Rachel Bennett, Westchester Reproductive Medicine, Opens New Office in Mount Kisco
2. Living with females extends the reproductive life of the male mouse, says Penn veterinary researcher
3. Seattle Reproductive Medicine Study Investigates Newly Formulated Medications for Luteal Support in IVF
4. Dr. Karen E. Boyle Joins Chesapeake Urology Associates as Director of Reproductive Medicine and Surgery, Sexuality and Aesthetics
5. Elsevier announces the 2008 supplement of Reproductive Health Matters
6. Experts at American Society for Reproductive Medicine (ASRM) Satellite Symposium Reach Consensus: Better Intimacy = Better Overall Well-Being
7. Fertility experts present the latest research at reproductive medicine meeting
8. Georgetown University Med Center reproductive health researchers tackle public health concerns
9. IVF Florida Reproductive Associates Offers IntegraMeds New Enhanced Refund Program for Donor Egg Recipients
10. Trends in Prescription Medication Sharing Among Reproductive-Aged Women Reported in Journal of Womens Health
11. May 2008 issue on conflict and crisis settings: Promoting sexual and reproductive rights
Post Your Comments:
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Comfort ... the American Cancer Society and the Road To Recovery® program to drive cancer patients ... seniors and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Living, is proud to recognize Dr. Barry M. Weintraub as a prominent plastic ... most beautiful women in the world, and the most handsome men, look naturally ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... is actively feeding the Frederick area economy by obtaining investment capital for emerging ... the past 2½ years that have already resulted in more than a million ...
(Date:6/24/2016)... ... ... Venture Construction Group (VCG) sponsors Luke’s Wings 5th Annual ... Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. The event raised funds ... been wounded in battle and their families. Venture Construction Group is a 2016 Silver ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  MedSource announced today ... its e-clinical software solution of choice.  This latest ... possible value to their clients by offering a ... preferred relationship establishes nowEDC as the EDC platform ... MedSource,s full-service clients.  "nowEDC has long been a ...
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... Analysis 2016 - Forecast to 2022" report to their ... contains up to date financial data derived from varied research ... trends with potential impact on the market during the next ... which comprises of sub markets, regional and country level analysis. ...
Breaking Medicine Technology: