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Reportlinker Adds Antibiotic Resistance and Antibiotic Technologies: Global Markets
Date:12/2/2009

F THE DIGESTIVE TRACT 25

CLASSIFICATION OF ANTIBIOTICS 25

BACTERICIDAL AND BACTERIOSTATIC 26

CLASSIFICATION BASED ON STRUCTURE 26

Penicillins 26

Cephalosporins 27

Fluoroquinolones 27

Tetracyclines 28

Macrolides 28

TABLE 4 COMMONLY USED ANTIBIOTICS BY CLASS 29

CLASSIFICATION BASED ON THE MODE OF ACTION OF ANTIBIOTICS 29

Cell Wall Inhibitors 29

Cell Membrane Inhibitors 30

Nucleic Acid Inhibitors 30

Protein Synthesis Inhibitors 30

TABLE 5 COMMONLY USED PROTEIN SYNTHESIS INHIBITORS 31

Metabolic Inhibitors 31

Fatty Acid Biosynthesis (Fab) Inhibitors 31

ADMINISTRATION OF ANTIBIOTICS 32

DETERMINING THE POTENCY OF ANTIBIOTICS 32

ANTIBIOTIC SUSCEPTIBILITY TESTING 32

DRUG RESISTANCE: THE GREATEST CHALLENGE FACING THE ANTI-INFECTIVE DRUG MARKET 33

THE HISTORY OF ANTIBIOTIC RESISTANCE 33

CURRENT CRISIS OF ANTIBIOTIC RESISTANCE 34

THE MICROBIOLOGY OF ANTIBIOTIC RESISTANCE 34

MECHANISMS OF RESISTANCE DEVELOPED BY VARIOUS BACTERIA 35

Enzymatic Deactivation or Modification of Antibiotic 35

ESBL-Producing Organisms 35

Alteration of the Target Site of the Antibiotic 36

Alteration of the Metabolic Pathways 36

Reducing the Potential for Drug Accumulation 36

Biofilm Formation 37

TABLE 6 HUMAN INFECTIONS INVOLVING BIOFILMS 37

RESISTANCE IN GRAM-POSITIVE BACTERIA 37

Methicillin-Resistant Staphylococcus Aureus (MRSA) 38

Vancomycin-Intermediate S. aureus (VISA) 38

Vancomycin-Resistant Enterococci (VRE) 38

Multi-Drug-Resistant Clostridium difficile 39

RESISTANCE IN GRAM-NEGATIVE BACTERIA 39

Multi-Drug-Resistant Acinetobacter Baumannii 40

Enterobacteriacae- (Re
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