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Renal risk index: A clinical tool to predict the risk of end-stage renal disease
Date:10/1/2013

ed that other factors, like serum sodium over 134 mEq/L at transplant were associated with a lower risk of post-transplant end-stage renal disease.

Sharma said the renal risk index is an objective score based upon readily available clinical and laboratory data that can help clinicians stratify liver transplant recipients into mild, moderate or high risk of post-liver transplant end-stage renal disease at the time of transplant.

"Knowledge of that future risk can help them reach making informed evidence-based decisions regarding post-transplant management including individualized tailoring of immunosuppression, stricter control of hypertension and diabetes, weight loss for obese patients as well as treatment of hepatitis C after transplant with newer antiviral agents," Sharma says.

"In the long run, risk stratification using renal risk index and risk modification among highest risk group can help prevent or delay the progression of kidney disease to end-stage renal disease and improve overall patient survival."

Sharma says future research should focus on using the renal risk index to personalize immunosuppression strategies and risk modification to improve patient outcomes.


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Contact: Mary Masson
mfmasson@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1 2

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