Navigation Links
Renal denervation treats resistant hypertension in real world patient populations
Date:8/27/2012

Munich, Germany August 27 2012: Renal denervation successfully treats patients with resistant hypertension in real world patient populations, according to a study presented at ESC Congress 2012. The findings were presented by Dr Darren Mylotte from France.

Transcatheter renal denervation represents a novel therapy for treating patients with treatment resistant hypertension, a condition which greatly increases the risk of myocardial infarction and stroke.

"The Symplicity Hypertension I and II studies have suggested that this procedure significantly lowers blood pressure in these patients with few remaining options in terms of treatment," said Dr Mylotte. "However, patients included in clinical trials are often highly selected, and therefore may not reflect the patient encountered by physicians on a day-to-day basis. As such, the results of these trials may not be applicable to less-selected patient populations."

In light of this potential problem, the investigators sought to evaluate the effect of transcatheter renal denervation in a group of patients with resistant hypertension in their own clinical practice at The Institut Cardiovasculaire de Paris Sud, Paris, France.

They intended to perform transcatheter renal denervation on 35 consecutive patients referred to the service with resistant hypertension. The study used the same definition as the Symplicity trials to define resistant hypertension (1).

Among these patients, 36.5% were female, 36.4% were diabetic, and 15.2% had kidney dysfunction. Baseline office blood pressure (BP) was 181.121.9 /100.816.8 mmHg, despite an average of 4.61.0 medications per patient. Successful bilateral sympathetic denervation was performed in 33 out of 35 patients (1 patient was not treated due to a stenosis of the renal artery; 1 patient had treatment on one side only, as multiple small renal arteries were found on the other side). No procedural complications occurred.

At 6-months follow-up, the average office BP reduction from baseline was 30.321.1/14.615.3 mmHg (P<0.0001). Similarly, ambulatory BP was reduced 23.312.1/10.29.9 mmHg from baseline (P<0.001). There were no adverse events during follow-up (death, myocardial infarction, or stroke), and no deterioration in renal function was observed.

"Transcatheter renal denervation is a safe and efficacious treatment, which results in significant reductions in blood pressure in real world patients with treatment resistant hypertension," said Dr Mylotte. "Although longer-term results are required, renal denervation should be considered for all patients with treatment resistant hypertension, as it is likely to lower their blood pressure and reduce their chances of myocardial infarction and stroke."


'/>"/>

Contact: ESC Press Office
press@escardio.org
European Society of Cardiology
Source:Eurekalert

Related medicine news :

1. Newborn Screening May Miss Adrenal-Gland Disorder
2. Broken heart syndrome protects the heart from adrenaline overload
3. Renal denervation gives better outcomes than drugs in advanced heart failure
4. Intense light prevents, treats heart attacks
5. Novel radiation therapy safely treats prostate cancer and lowers the risk of recurrence
6. Kinase test may yield big gains for drug-resistant cancers
7. New drug strategy attacks resistant leukemia and lymphoma
8. Einstein awarded $6 million grant to develop new TB vaccine against drug-resistant strains
9. New Medicine Might Fight Drug-Resistant TB, Study Says
10. Antibiotic-Resistant Gonorrhea Spreading: WHO
11. Rare Drug-Resistant Bacteria Spotted in U.S. Hospital
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... ... May 23, 2017 , ... New England Journal Of Medicine Confirms ... a Policy Response”, -The Rory Staunton Foundation Calls on Health & Human Services, Tom ... of Sepsis ( http://www.rorystauntonfoundation.org ) today reported on a new study released on May ...
(Date:5/23/2017)... ... May 23, 2017 , ... By all indications, and due to ... While officials call for diligence, asking homeowners to scout for any open water sources ... Along with the annoying buzz of mosquitos is the buzz associated with potential infections ...
(Date:5/23/2017)... ... May 23, 2017 , ... Orbita’s Nathan Treloar will discuss the ... in San Francisco. Titled Connected Health and IoT: Technology Innovators and Disruption , ... by Parks Associates, a market research and consulting firm specializing in emerging consumer technology ...
(Date:5/22/2017)... ... May 22, 2017 , ... The American Academy ... development, healthcare training and clinical application of medical infrared imaging, has announced two ... medical thermal imaging services. , The first new educational offering is an online ...
(Date:5/22/2017)... ... May 22, 2017 , ... “Homeostasis: The Journey of a Manic-Depressive” tells ... Bipolar 1. Donald Rodriguez takes readers on a rollercoaster ride that includes a midnight ... winter and to a dark place where Donald considers suicide. Readers learn how ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... , May 4, 2017 Clarius Mobile ... wireless, handheld ultrasound scanners this week at the ... Meeting (ACOG) in San Diego, CA ... "Clarius is the perfect tool for clinicians ... heart rate, and evaluate pregnancy-related complications like ectopic ...
(Date:5/4/2017)... 2017  A new tight-tolerance microextrusion medical tubing ... materials, is being launched by Natvar, a Tekni-Plex ... in recent years to service a wide variety ... More expensive materials such as glass and fluoropolymers ... to their ability to consistently hold tolerances. This ...
(Date:5/3/2017)... , May 3, 2017  Kalorama Information notes ... nine percent next year and this is projected ... hematopoietic stem cell (HSCT) or bone marrow transplants ... technologies are well-suited for this task. This according ... publisher Kalorama Information. The various PCR-based methodologies, Sanger ...
Breaking Medicine Technology: