Navigation Links
Remove Diabetes Drug Avandia From Market: FDA Documents
Date:2/20/2010

Controversial medicine raises users' heart risk, leaked files suggest

SATURDAY, Feb. 20 (HealthDay News) -- The blockbuster type 2 diabetes drug Avandia raises users' odds for heart attack and heart failure and should be removed from the market, according to confidential government reports.

The New York Times on Saturday reported on documents from the U.S. Food and Drug Administration that find that if people now taking (rosiglitazone) Avandia switched to a similar medication, Actos, about 500 heart attacks and 300 cases of heart failure would be eliminated each month. And in a report from the Institute for Safe Medication Practice, Avandia was linked to 304 deaths in the third quarter of 2009 alone, the highest for any prescribed drug in that time period, the Times reported.

In one of the FDA documents, dated October 2008, Drs. David Graham and Kate Gelperin -- drug safety officials at the agency -- agreed that "rosiglitazone should be removed from the market."

The reports, obtained early by the Times, are yet another chapter in Avandia's checkered history. The drug was once taken by millions worldwide, but that changed after a study released in early May of 2007 by the Cleveland Clinic suggested that Avandia carried cardiovascular risks. That study, which included more than 28,000 people, found that Avandia increased a user's odds of heart attack by 43 percent compared to those not taking the medicine.

At the time, Dr. Bruce M. Psaty of the University of Washington -- who also co-wrote an accompanying editorial in the New England Journal of Medicine -- urged the FDA to restrict access to Avandia and cited both the agency and the drug's maker, GlaxoSmithKline, for poor oversight.

"The primary problem here is that studies that were needed early on about the health benefits of this drug were never done," Psaty told HealthDay. "As a result of the failure of the
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Single-incision belly-button surgery to remove kidney performed first at UT Southwestern
2. Surgeons Remove Gallbladder Through Vagina
3. CVS/pharmacy to Remove OTC Infant Cough & Cold Products from Its Stores as Part of CHPAs Voluntary Withdrawal
4. Prominent Farmington Plastic Surgeon Uses Two New Non-Surgical Procedures to Tighten Skin and Remove Fat
5. Stop & Shop Removes Childrens Cough and Cold Medicine from Store Shelves
6. Giant Food Removes Childrens Cough and Cold Medicine From Store Shelves
7. Schwarzenegger Signs Bill to Remove Written Informed Consent for HIV Testing; "Most Important Change in Public HIV/AIDS Policy in Years," Says AHF
8. Health Groups Call on Cosmetic Giant LOreal to Remove Lead From Lipstick
9. Video: Trinity Mother Frances Neurosurgeon First in Region to Remove Brain Tumor Using Unique Surgical Procedure
10. Nations Largest Pet Insurer Reveals Top 10 Items Surgically Removed From Pets
11. Safety Concerns Prompt Prime to Remove Avandia(R) from Formulary
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... As reported by Wood TV 8 in the article ... a nearly 500-person increase in heroin related overdose deaths in ... 1999 and 2002, the toll increased to 728 during the ... drug users in Michigan have turned to heroin after getting ... price of both substances, noting that an 80-milligram pill can ...
(Date:7/25/2014)... 2014 (HealthDay News) -- The human brain can preserve ... a new study finds. Although dehydration significantly ... have found that the brain compensates by increasing the ... "This research has helped us understand a lot more ... in extreme conditions," study first author Steven Trangmar, a ...
(Date:7/25/2014)... Ticket Down is a reliable source ... Berkeley at California Memorial Stadium. With the post-World Cup ... the organizers of the 2014 Guinness International Champions Cup have ... America. With teams representing La Liga, English Premier League, Serie ... the best football players from around the world to 12 ...
(Date:7/25/2014)... July 25, 2014 This is ... state of the Galactooligosaccharides (GOS) industry in ... overview of the industry, including definitions, applications and ... domestic market analysis are provided with a focus ... the market. A comparison between the international and ...
(Date:7/25/2014)... 25, 2014 (HealthDay News) -- Babies seem to learn ... By the time women are 34 weeks pregnant, their ... mother,s voice reciting a familiar nursery rhyme, the researchers ... of sensory stimulation in the developing fetus," Charlene Krueger, ... Florida,s College of Nursing, said in a university news ...
Breaking Medicine News(10 mins):Health News:Rise in Heroin Use, Overdose Deaths in Michigan 2Health News:Human Brain Has Coping Mechanism for Dehydration 2Health News:Real Madrid vs. Inter Milan Tickets Berkeley: Ticket Down Slashes Ticket Prices on Guinness International Champions Cup Tickets at California Memorial Stadium 2Health News:Real Madrid vs. Inter Milan Tickets Berkeley: Ticket Down Slashes Ticket Prices on Guinness International Champions Cup Tickets at California Memorial Stadium 3Health News:GOS Market (Galacto-oligosaccharides) Development in Global & China Regions Now Available at DeepResearchReports.com 2Health News:GOS Market (Galacto-oligosaccharides) Development in Global & China Regions Now Available at DeepResearchReports.com 3Health News:Rhymes Reveal Evidence of Learning in the Womb 2
... , , , , ... (Nasdaq: STXS ) today announced that its Board of Directors ... effective November 15, 2009. He will join Stereotaxis in September, 2009 ... will retire from the Company effective at year end 2009. Mr. ...
... , , , ... (Nasdaq: STXS ) today reported improved financial results for the ... quarter totaled $12.6 million, an increase of 19% over the $10.7 million ... Company recognized revenue on eight Niobe(R) Magnetic Navigation Systems and two Odyssey(TM) ...
... Tinnitus Sufferer ... ... of a deep-sleep to a high pitch ringing sound in your ear, or constantly hearing ... reality for millions of men and women who suffer from the medical condition tinnitus, often ...
... ... can now access comprehensive pharmacology information and fast drug interaction screening tools tailored to ... ... publisher of clinical resources for the dental market, has released Lexi-Comp® ONLINE™ for ...
... ... charity, received another $300,000 in donations from network marketing icon, Tom Mower, making total ... frenzy of contributions by others. , ... Springville, UT (PRWEB) August 6, 2009 -- Tom Mower Sr., a ...
... ... the benefit of the community through various events and initiatives. For example, on June 20, ... to the Round Rock Express, to support to the Round Rock Express AAA Minor League ... Austin, TX ...
Cached Medicine News:Health News:Stereotaxis Names Daniel Johnston as Chief Financial Officer 2Health News:Stereotaxis Names Daniel Johnston as Chief Financial Officer 3Health News:Stereotaxis Reports 19% Second Quarter Revenue Growth 2Health News:Stereotaxis Reports 19% Second Quarter Revenue Growth 3Health News:Stereotaxis Reports 19% Second Quarter Revenue Growth 4Health News:Stereotaxis Reports 19% Second Quarter Revenue Growth 5Health News:Stereotaxis Reports 19% Second Quarter Revenue Growth 6Health News:Stereotaxis Reports 19% Second Quarter Revenue Growth 7Health News:Stereotaxis Reports 19% Second Quarter Revenue Growth 8Health News:Lipo-Flavonoid Launches New Video Testimonial 2Health News:Lipo-Flavonoid Launches New Video Testimonial 3Health News:Lexi-Comp ONLINE™ for Oral Surgery 2Health News:Lexi-Comp ONLINE™ for Oral Surgery 3Health News:Orphanage Receives Nearly $1 Million from Private Donor 2Health News:Orphanage Receives Nearly $1 Million from Private Donor 3Health News:HealthYes! Provides Free Preventive Screening in Support of Round Rock Express 2Health News:HealthYes! Provides Free Preventive Screening in Support of Round Rock Express 3
(Date:7/25/2014)... /PRNewswire-iReach/ -- Full Service CRO WCCT Global ... President of Business Development. Peter has been in the ... of different business development positions with some of the ... related to business development/sales management and marketing.  The experience ... him a key and strategic asset to WCCT Global ...
(Date:7/25/2014)... July 25, 2014  Acsis Inc., the market ... serialization solutions, has recently posted an article, ... current and future needs for companies, extended supply ... supply chain model no longer work today.  The ... the growth of mobile technology, machine to machine ...
(Date:7/25/2014)... 25, 2014  IDEXX Laboratories, Inc. (NASDAQ: ... quarter of 2014 increased 11% versus the prior year ... for the second quarter of 2014 versus the prior ... in distributor inventory 2 . Earnings per diluted share ... 11% from the prior year period to $1.10."In the ...
Breaking Medicine Technology:Contract Research Organization WCCT Global Welcomes Peter Nieto as Vice President of Business Development 2Acsis Addresses Questions on the Modern Supply Chain 2IDEXX Laboratories Announces Second Quarter Results 2IDEXX Laboratories Announces Second Quarter Results 3IDEXX Laboratories Announces Second Quarter Results 4IDEXX Laboratories Announces Second Quarter Results 5IDEXX Laboratories Announces Second Quarter Results 6IDEXX Laboratories Announces Second Quarter Results 7IDEXX Laboratories Announces Second Quarter Results 8IDEXX Laboratories Announces Second Quarter Results 9IDEXX Laboratories Announces Second Quarter Results 10IDEXX Laboratories Announces Second Quarter Results 11IDEXX Laboratories Announces Second Quarter Results 12IDEXX Laboratories Announces Second Quarter Results 13IDEXX Laboratories Announces Second Quarter Results 14IDEXX Laboratories Announces Second Quarter Results 15IDEXX Laboratories Announces Second Quarter Results 16IDEXX Laboratories Announces Second Quarter Results 17IDEXX Laboratories Announces Second Quarter Results 18IDEXX Laboratories Announces Second Quarter Results 19IDEXX Laboratories Announces Second Quarter Results 20IDEXX Laboratories Announces Second Quarter Results 21IDEXX Laboratories Announces Second Quarter Results 22IDEXX Laboratories Announces Second Quarter Results 23IDEXX Laboratories Announces Second Quarter Results 24IDEXX Laboratories Announces Second Quarter Results 25IDEXX Laboratories Announces Second Quarter Results 26IDEXX Laboratories Announces Second Quarter Results 27IDEXX Laboratories Announces Second Quarter Results 28IDEXX Laboratories Announces Second Quarter Results 29IDEXX Laboratories Announces Second Quarter Results 30IDEXX Laboratories Announces Second Quarter Results 31IDEXX Laboratories Announces Second Quarter Results 32IDEXX Laboratories Announces Second Quarter Results 33IDEXX Laboratories Announces Second Quarter Results 34
... Inc. (NYSE: WPI ), a leading integrated global ... its first quarter 2011 financial results on Wednesday, April 27, ...  The Company will also host a conference call and webcast ... discuss its financial results and provide an update on the ...
... STAUNTON, Va., April 5, 2011 Cadence is pleased ... as President.  Alan joins the company following years in ... companies, including most recently as the Vice President and ... in Charlottesville, Virginia. Prior to his role ...
Cached Medicine Technology:Watson to Host Conference Call and Webcast to Discuss First Quarter 2011 Earnings 2
... been selling replacement bulbs on ... we are extremely proud of ... out our catalog of replacement ... light bulbs specials. ,Check ...
... has been selling replacement bulbs ... and we are extremely proud ... Check out our catalog of ... discount light bulbs specials. ...
... been selling replacement bulbs on ... we are extremely proud of ... out our catalog of replacement ... light bulbs specials. ,Check ...
... has been selling replacement bulbs ... and we are extremely proud ... Check out our catalog of ... discount light bulbs specials. ...
Medicine Products: