Navigation Links
Remote-control closed system invented for inserting radio-active atoms inside fullerenes
Date:7/7/2009

n further purified by passage through a column that traps the empty-cage fullerenes. The resulting liquid is evaporated and hydroxyl atoms are attached to the molecules so they will be soluble in biofluids.

All of the steps of the process are managed remotely and the purified product is decanted into a shielded container.

Dorn and Duchamp have used non-radioactive Lu to produce the trimetallic nitride endohedral metallofullerenes (Lu3N@C80) in other words, three atoms of Lu attached to a nitrogen atom inside an 80-atom carbon molecule cage. Once the apparatus is at VCU, Fatouros will use isotope 177Lu, which is used to treat cancer. Although other details need to be worked out, Dorn is confident the generator will work just as well with the radiolabeled product and will produce (177Lu3N@C80).

It all takes less than a day, which is important because 177Lu has a half life of six and one-half days. "So we can't take 30 days to make the product," said Duchamp.

It will be the first time that 177Lu has been encapsulated in a fullerene and the first time any radioactive metal has been encapsulated under remote control with direct purification to a pure product.

"The advantage of the metal cage is we can control where it goes biologically," Dorn said.

"We believe it will mean fewer side effects with better targeted localization, but that remains to be tested," said Fatouros.

"Another advantage is we can deliver other materials inside the fullerene with the 177Lu such as a targeting agent (interleukin-13) and an MRI contrast agent," said Dorn.

Creation of such a multi-modality material for use on brain tumors is a specific goal of Fatouros and Dorn's NCI-funded research project, "Metallofullerene imaging and targeting of glioma." "The MRI agent lets you see where you are going and the 177Lu lets you treat an exact region," said Dorn. "The imaging ability also lets you see if the tumor is shrinking
'/>"/>

Contact: Susan Trulove
STrulove@vt.edu
540-231-5646
Virginia Tech
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Remote-control health
2. Gain Entry to the Closed 2009 Chicago Marathon by Joining Susan G. Komens Marathon for the Cure(R)
3. Rarely Used Closed Doors Slammed Again in U.S. Senate Health Care Reform; Sen. Max Baucus Must Publicly Answer 10 Questions About Mandatory Purchase of Health Insurance
4. Dissident Stockholder Ted Karkus Found to Have Undisclosed Financial Arrangements With Dr. Richard A. Rosenbloom, COO Of Quigley Pharma, From 2008 to Date of Proxy: Rosenbloom Suspended Without Pay Pending Further Investigation
5. Closing Open Heart Surgery: Saint Josephs Performs Georgias First Totally-Closed, Beating Heart Bypass Surgery
6. AIM Health Group Inc. and Med-Emerg International Inc. Announce Completion of Previously Disclosed Merger Transaction
7. PARI Pharma Unveils Closed System Using eFlow Technology at Medical Plastics Conference
8. NCRA Urges U.S. Reps. Danny Davis and Judy Biggert to Approve in Conference the Higher Education Reauthorization Bill Providing Closed Captioning for 30 Million Deaf and Hard-of-Hearing Americans
9. NCRA Urges Congressman David Wu to Approve in Conference the Higher Education Reauthorization Bill Providing Closed Captioning for 30 Million Deaf and Hard-of-Hearing Americans
10. Previously Disclosed Changes in Board Composition of NightHawk Radiology Holdings, Inc. Prompt Notice of Noncompliance from the Nasdaq Global Market
11. HealthSouth Announces Final Agreement on Previously Disclosed Settlement with Federal Government
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Remote-control closed system invented for inserting radio-active atoms inside fullerenes
(Date:4/23/2014)... NY, April 23, 2014Men whose testosterone falls below normal ... to be overweight and have heart disease and type ... identify testosterone-deficient men for further testing and possible treatment ... Men,s Health , a peer-reviewed publication from Mary Ann ... the Journal of Men,s Health website at ...
(Date:4/23/2014)... (April 23, 2014) The American Gastroenterological Association ... 2014 AGA Research Scholars. The AGA Research Scholar ... to develop independent and productive research careers in ... Awards fund an additional year allowing for three ... to supporting junior faculty who are paving the ...
(Date:4/23/2014)... country as wealthy as the United States, it may come ... have access to adequate food due to lack of money ... Recent research at the University of Illinois using data from ... the seniors who are dealing with hunger are also facing ... percent of Americans over age 60 faced the threat of ...
(Date:4/23/2014)... about an increase in adolescents, marijuana use following the ... relief. According to a new study at Rhode Island ... states with and without medical marijuana laws, legalizing the ... The study is published online in advance of print ... , "Any time a state considers legalizing medical marijuana, ...
(Date:4/23/2014)... may prevent the depletion of self-control, according to research ... the Association for Psychological Science. , Self-control can be ... focus attention on a boring textbook are hard things ... this difficulty: Exerting self-control for a long period seems ... subsequent tasks. , "It is as if self-control is ...
Breaking Medicine News(10 mins):Health News:AGA announces 2014 Class of AGA Research Scholars 2Health News:More Americans in their golden years are going hungry 2Health News:RI Hospital physician: Legalizing medical marijuana doesn't increase use among adolescents 2Health News:ADHD drug may help preserve our self-control resources 2
... The world's leading climate experts and state representatives from ... meet on the UN's recommendations for curbing// carbon emissions ... now," said Chartree Chueytrasit, deputy permanent secretary of Thailand's ... at the UN's Intergovernmental Panel on Climate Change (IPCC). ...
... focus on cars or factories. Yet a study commissioned ... production plants must run worldwide just to provide electricity ... PCs in private or corporate settings to be figured ... disposal of the machines, all of which damage the ...
... chemotherapy drug has recently been tested in 950 ... found //to have significant improvement in Progression-Free Survival. ... Phase III trial on Satraplatin has shown: ... in Progression-Free Survival ,* Progression-Free ...
... get married is a waste of breath, a US expert ... // ,William Smith, the vice president of the Sexuality, ... a six-year study commissioned by the US Congress found that ... on pushing sexual abstinence outside marriage had had no discernible ...
... for health, Indiana legislators in the US have decided on ... healthcare. // ,As per a deal agreed upon on ... cents per pack and the expected additional flow to the ... would help fund several health programs. ,Most of ...
... of successive Australian governments, a report commissioned by the ... lags an appalling one century behind that of the ... have significantly worse outcomes than their fellow countrymen on ... while inequality exists between Maori and non-Maori the gaps ...
Cached Medicine News:Health News:Study Focus on Environmental Hazards Posed by IT Scraps 2Health News:Satraplatin Benefits Hormone Refractory Prostate Cancer Patients 2Health News:Satraplatin Benefits Hormone Refractory Prostate Cancer Patients 3Health News:Satraplatin Benefits Hormone Refractory Prostate Cancer Patients 4Health News:Satraplatin Benefits Hormone Refractory Prostate Cancer Patients 5Health News:Smokers to Be Taxed to Fund Healthcare for Uninsured 2Health News:Aborigines Century Behind the Health of Colonizers, WHO Report 2
(Date:1/15/2014)... , Jan. 15, 2014  Manufacturers, suppliers and distributors ... able to protect their most important business assets, ... ) Because of the highly-competitive ... remains one of the most litigious industry sectors ...
(Date:1/15/2014)... 15, 2014 The Cadence Fitness & Health Center ... the Medical Fitness Association, a non-profit organization assisting medically ... potential. The Cadence Fitness & Health Center is the ... second in the Chicagoland area. "The certification ...
(Date:1/15/2014)... NEW YORK , Jan. 15, 2014 ... research report is available in its catalogue: ... Technologies for Advanced Drug Delivery Systems -- ... http://www.reportlinker.com/p01940411/Global-Markets-and-Technologies-for-Advanced-Drug-Delivery-Systems----Focus-on-End-Users.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology STUDY OBJECTIVES ...
Breaking Medicine Technology:Intellectual Property Insurance for Medical-related Products and Services 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 16Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 18
... April 20 Scientists from the Barbara ... presented data at the American Association for ... represents significant research advancements in the treatment ... breast cancer.(Logo: http://www.newscom.com/cgi-bin/prnh/20071106/KARMANOSLOGO )Karmanos researchers discovered ...
... Improves Survival in Animals with Clinical Symptoms of ... 20 Elusys Therapeutics, Inc. (Elusys), ... the treatment of life-threatening infectious diseases, today announced ... safety trial of Anthim(TM), a high-affinity humanized ...
Cached Medicine Technology:Karmanos Cancer Institute Researchers Present Breast Cancer Advancements at Conference 2Karmanos Cancer Institute Researchers Present Breast Cancer Advancements at Conference 3Elusys' Anthrax Anti-Toxin, Anthim(TM), Enters Second Phase I Clinical Study 2Elusys' Anthrax Anti-Toxin, Anthim(TM), Enters Second Phase I Clinical Study 3
... products for autoimmune testing feature single-well ANA ... as specific reflex tests including dsDNA, and ... (Ro), SS-B (La), Scl-70 and Jo-1. In ... full line of products for Cardiolipins (IgA, ...
... ELISA products for autoimmune testing feature single-well ... well as specific reflex tests including dsDNA, ... SS-A (Ro), SS-B (La), Scl-70 and Jo-1. ... a full line of products for Cardiolipins ...
... ELISA products for autoimmune testing feature single-well ... well as specific reflex tests including dsDNA, ... SS-A (Ro), SS-B (La), Scl-70 and Jo-1. ... a full line of products for Cardiolipins ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: