Navigation Links
Rehabilitation therapies can lead to recovery from chronic fatigue syndrome
Date:1/31/2013

Research led by Queen Mary, University of London, has shown that recovery from chronic fatigue syndrome (CFS) is possible for some patients, and has identified two treatments most likely to lead to recovery.

The latest results from the PACE trial* show that cognitive behaviour therapy (CBT) and graded exercise therapy (GET), as supplements to specialist medical care, increase the likelihood of recovery from CFS three-fold compared to other treatments studied. The trial, carried out in collaboration with researchers from King's College London, the University of Oxford and the Medical Research Council (MRC), is published today in Psychological Medicine.

CFS is a long-term and debilitating condition that affects around 250,000 people in the UK. Symptoms include profound physical and mental fatigue (characteristically made worse by exertion), muscle and joint pain, disturbed sleep and both concentration and memory problems. The researchers studied 640 participants with CFS who were randomised into one of four treatment groups:

  • Specialist medical care (SMC) alone;
  • SMC plus adaptive pacing therapy (APT);
  • SMC plus cognitive behavioural therapy (CBT);
  • SMC plus graded exercise therapy (GET)

Evidence for recovery was assessed one year after participants were randomly allocated to treatments.

Previous published results showed that both CBT and GET led to greater reductions in symptoms and disability than either APT or SMC. In this analysis the researchers have gone a step further and examined how many patients had recovered from their illness after these treatments. Patients were classed as recovered if they no longer met several criteria for ill health which were initially used to define eligibility for the trial. These included not suffering from significant fatigue or physical disability, and no longer meeting diagnostic criteria for CFS. Patients also had to rate themselves as being "much" or "very much better" in their overall health.

The findings showed that those who received CBT or GET, in addition to SMC, were three times more likely to meet the criteria for recovery than those receiving SMC alone or in combination with APT. Overall 22 per cent of those who received either CBT or GET, in addition to SMC, met the criteria for recovery, compared to eight per cent after APT in addition to SMC, and seven per cent after SMC alone. There were similar patterns of recovery however CFS was defined, including those who were diagnosed as having myalgic encephalomyelitis (ME), thought by some to be the same as CFS and by others as being different.

Peter White, Professor of Psychological Medicine at Barts and the London School of Medicine and Dentistry, part of Queen Mary, was the lead co-principal investigator of the PACE trial and co-author of the latest paper.

Professor White said: "This is good news and shows that recovery from this debilitating condition is possible for some patients. We now need to go further to understand why only a relatively small proportion of patients recover, which shows how much this condition varies between individuals; one treatment is unlikely to work for everyone.

"Some people may question the use of the term 'recovery', and how to define when a patient is 'recovered' was a key issue we faced. We focussed on recovery from the current episode of the illness and used several measures of both symptoms and disability to give us the most complete picture possible. Further analysis is needed to see if recovery is sustained in the long-term."

Professor Michael Sharpe, University of Oxford co-principal investigator of the PACE trial and co-author of the latest paper, said: "The rehabilitative treatments of CBT and GET for CFS have been controversial. This analysis of the PACE trial data shows that not only do they achieve improvements in the majority, but that they can also lead to recovery in a substantial minority."

Professor Trudie Chalder from King's College London's Institute of Psychiatry, said: "The fact that people can recover from chronic fatigue syndrome is excellent news. Healthcare professionals can now be more confident in sharing this possibility with patients, many of whom are understandably concerned about their future."


'/>"/>

Contact: Katrina Coutts
k.coutts@qmul.ac.uk
Queen Mary, University of London
Source:Eurekalert

Related medicine news :

1. Rehabilitation Continuing Education Provider HomeCEUConnection.com Qualifies to Offer Interactive Continuing Education For Florida Occupational Therapists
2. Drug abuse impairs sexual performance in men even after rehabilitation
3. Best Drug Rehabilitation CEO Launches Boxing Program to Steer Kids away from Drugs and Alcohol
4. Best Drug Rehabilitation's New Indiana Facility to Create Dozens of Quality Long-Term Jobs
5. Best Drug Rehabilitation to Open New Facility in March 2013
6. Dr. Chiaravalloti of Kessler Foundation comments on trends in rehabilitation research in MS
7. Scientists report promising new direction for cognitive rehabilitation in the elderly
8. The Journal of Injury, Function and Rehabilitation to be covered in Reuters Indexing Database
9. Study suggests changes in rotator cuff surgery rehabilitation needed
10. International symposium on veterinary rehabilitation and physical therapy to be held in Vienna
11. Coronary rehabilitation programs in Europe are underused
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... New York, NY (PRWEB) , ... May 27, ... ... has partnered with Mediaplanet to help educate the many who are unaware of ... section dedicated to aphasia will run within the “Stroke Awareness” campaign. , The ...
(Date:5/27/2016)... ... May 27, 2016 , ... Each year ... medicine. Allison Outerbridge is this year’s Life University winner of a ... the university’s Student Leadership Awards ceremony. , Outerbridge is approaching her last quarter ...
(Date:5/26/2016)... , ... May 26, 2016 , ... W.S. Badger ... has been honored with a 2016 When Work Works Award for its use of ... of the national When Work Works project administered by the Families and Work Institute ...
(Date:5/26/2016)... ... ... Connor Sports, through its Connor Cares initiative, will continue to expand ... Tour that will commemorate the Indiana Fever legend’s hall-of-fame career and final WNBA ... levels of the game, Connor Sports has committed to a significantly increased focus on ...
(Date:5/26/2016)... , ... May 26, 2016 , ... There are nearly ... than 32 million cancer survivors worldwide. On Sunday, June 5, 2016, communities around the ... National Cancer Survivors Day®. , National Cancer Survivors Day® is an annual worldwide ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... -- According to a new market research ... by Therapeutic Area (Oncology, Cosmeceutical/Plastic Surgery), by Application (Drug ... Hospitals/ Clinics) - Forecast to 2021", published by MarketsandMarkets, ... the forecast period of 2016 to 2021. This market ... from USD 117.3 Million in 2016, at a CAGR ...
(Date:5/25/2016)... Germany and GERMANTOWN, Maryland ... N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: QIA) ... and co-development agreement with Therawis Diagnostics GmbH to develop and ... to develop and market PITX2 as a marker to predict ... breast cancer patients. "We are pleased to partner ...
(Date:5/25/2016)... , May 25, 2016  According to Kalorama ... $381 billion in 2015.  Though these are challenging ... of opportunity for success for companies that remain ... search of new growth prospects medical device companies ... research and development (R&D) than do companies in ...
Breaking Medicine Technology: