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Rehabilitation therapies can lead to recovery from chronic fatigue syndrome
Date:1/31/2013

Research led by Queen Mary, University of London, has shown that recovery from chronic fatigue syndrome (CFS) is possible for some patients, and has identified two treatments most likely to lead to recovery.

The latest results from the PACE trial* show that cognitive behaviour therapy (CBT) and graded exercise therapy (GET), as supplements to specialist medical care, increase the likelihood of recovery from CFS three-fold compared to other treatments studied. The trial, carried out in collaboration with researchers from King's College London, the University of Oxford and the Medical Research Council (MRC), is published today in Psychological Medicine.

CFS is a long-term and debilitating condition that affects around 250,000 people in the UK. Symptoms include profound physical and mental fatigue (characteristically made worse by exertion), muscle and joint pain, disturbed sleep and both concentration and memory problems. The researchers studied 640 participants with CFS who were randomised into one of four treatment groups:

  • Specialist medical care (SMC) alone;
  • SMC plus adaptive pacing therapy (APT);
  • SMC plus cognitive behavioural therapy (CBT);
  • SMC plus graded exercise therapy (GET)

Evidence for recovery was assessed one year after participants were randomly allocated to treatments.

Previous published results showed that both CBT and GET led to greater reductions in symptoms and disability than either APT or SMC. In this analysis the researchers have gone a step further and examined how many patients had recovered from their illness after these treatments. Patients were classed as recovered if they no longer met several criteria for ill health which were initially used to define eligibility for the trial. These included not suffering from significant fatigue or physical disability, and no longer meeting diagnostic criteria for CFS. Patients also had to rate themselves as being "much" or "very muc
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Contact: Katrina Coutts
k.coutts@qmul.ac.uk
Queen Mary, University of London
Source:Eurekalert

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