Navigation Links
Regenerative medicine: Mayo Clinic and collaborators develop new tool for transplanting stem cells
Date:12/16/2013

ROCHESTER, Minn. -- Mayo Clinic researchers and colleagues in Belgium have developed a specialized catheter for transplanting stem cells into the beating heart. The novel device includes a curved needle and graded openings along the needle shaft, allowing for increased distribution of cells. The result is maximized retention of stem cells to repair the heart. The findings appear in the journal Circulation: Cardiovascular Interventions.

"Although biotherapies are increasingly more sophisticated, the tools for delivering regenerative therapies demonstrate a limited capacity in achieving high cell retention in the heart," says Atta Behfar, M.D., Ph.D., a Mayo Clinic cardiology specialist and lead author of the study. "Retention of cells is, of course, crucial to an effective, practical therapy."

Researchers from the Mayo Clinic Center for Regenerative Medicine in Rochester and Cardio3 Biosciences in Mont-Saint-Guibert, Belgium, collaborated to develop the device, beginning with computer modeling in Belgium. Once refined, the computer-based models were tested in North America for safety and retention efficiency.

What's the significance?

  • The new curved catheter eliminates backflow and limits loss of cells
  • Graded small to large side holes limit pressures in the heart to keep cells targeted
  • The design has proved to be more effective in both healthy and damaged hearts

This new catheter is being used in the European CHART-1 clinical trials, now underway. This is the first Phase III trial to regenerate hearts of patients who have suffered heart attack damage. The studies are the outcome of years of basic science research at Mayo Clinic and earlier clinical studies with Cardio3 BioSciences and Cardiovascular Centre in Aalst, Belgium, conducted between 2009 and 2010.


'/>"/>

Contact: Jennifer Schutz
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1

Related medicine news :

1. More Efficient Way to Grow Heart Muscle from Stem Cells Could Yield New Regenerative Therapies
2. Regenerative Agriculture Products & Services Company, Advancing Eco Agriculture, Discuss Initiative to Test Regenerative Practices to Restore Soil Quality
3. Mayo Clinic researchers apply regenerative medicine to battlefield injuries
4. Institute for regenerative medicine to lead national effort to aid wounded warriors
5. Regenerative Medicines: Bone and Joint Applications
6. The American Academy of Anti-Aging Medicine (A4M) Will Travel to Bangkok Congress on Anti-Aging and Regenerative Medicine September 6-8, 2013 for Largest Asian Event
7. New Biotechnology Report: Regenerative Medicine Markets
8. Gene therapies for regenerative surgery are getting closer, says review in PRS
9. The Institute of Regenerative & Molecular Orthopedics Applauds Newly Released Study on Platelet-Rich Plasma
10. Not all stem cells are equally efficient for use in regenerative medicine
11. Regenerative medicine: Clinical trials launched for the treatment of delayed union fractures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... ... 08, 2016 , ... Vida Health, the digital health platform that ... Canvas Ventures . Other investors include Nokia Growth Partners (NGP) and returning investor ... more consumers who are managing chronic conditions or simply want to improve ...
(Date:12/8/2016)... Cincinnati, OH (PRWEB) , ... December 08, 2016 ... ... offering insurance and financial planning services from offices headquartered in Hamilton County, is ... animal rescue LuvFurMutts. , LuvFurMutts specializes in finding new homes for orphaned or ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... that serve communities in and around the greater Phoenix metropolitan region, is announcing ... Connection. , The mission of the Homeless Youth Connection is to promote community ...
(Date:12/8/2016)... ... December 08, 2016 , ... The Compretta Insurance Agency, a ... clients in and around the Hancock County area, is announcing the launch of a ... Pantry. , The Hancock County Food Pantry has worked for more than 30 years ...
(Date:12/8/2016)... ... 2016 , ... Bill Mull Agencies, a Wichita-based firm offering ... central Kansas, is joining the Youth Horizons organization for a charity event that ... Wichita, Youth Horizons works to empower area children from unstable, troubled, or single-parent ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... Dec. 8, 2016 True Health Diagnostics ... leading-edge laboratory services and management expertise to hospital ... , allowing more doctors and patients to benefit ... solutions. Logo - http://photos.prnewswire.com/prnh/20161208/447162LOGO ... systems, under pressure to contain costs, have struggled ...
(Date:12/8/2016)... Inc . hat die behördliche Zulassung durch die CFDA sowie die Produkteinführung ... China angekündigt. ... ... Live Stretta procedure performed and broadcast during the Chinese Congress of Digestive ... , ...
(Date:12/8/2016)... 8, 2016 Dignitana, a world leader in ... Boa® Technology, creator of the award-winning, patented Boa® system, ... with the DigniCap® scalp cooling system. DigniCap® was cleared ... 2015, and is the first medical scalp cooling device ... cooling system features a patented tight-fitting silicone cooling cap ...
Breaking Medicine Technology: