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Regenerative Medicines: Bone and Joint Applications
Date:9/19/2013

2 SUMMARY 7

SUMMARY TABLE U.S. MARKET FOR REGENERATIVE MEDICINE PRODUCTS USED IN
BONE AND JOINT APPLICATIONS, THROUGH 2018 ($ MILLIONS) 8
SUMMARY FIGURE U.S. MARKET FOR REGENERATIVE MEDICINE PRODUCTS USED
IN BONE AND JOINT APPLICATIONS, 2012-2018 ($ MILLIONS) 8

CHAPTER 3 OVERVIEW AND OVERALL STATUS OF THE INDUSTRY 10

TOTAL SCOPE OF REGENERATIVE MEDICINE MARKET 10
ESTIMATED NUMBER OF COMPANIES IN REGENERATIVE SECTOR 10
TABLE 1 FUNCTIONAL ACTIVITIES WITH REGENERATIVE MEDICINE SECTOR 11
SIZE OF ORTHOPEDIC SECTOR AND LEADING SUPPLIERS 12
TABLE 2 2012 REVENUES FOR TOP SUPPLIERS OF ORTHOPEDIC PRODUCTS AND
MATERIALS ($ BILLIONS) 12
HOW REGENERATIVE MEDICINE WORKS 12
TISSUES AND ORGANS ON DEMAND 13
ORGAN REPLACEMENT IS A $100 BILLION PER YEAR BUSINESS 14
EXAMPLE IMPACT ON EXISTING CONDITIONS AND DISEASES 14
BARRIERS TO REGENERATIVE MEDICINE 14
TABLE 3 TEN PRINCIPAL MARKET DRIVERS (RANKED, MOST SIGNIFICANT TO LEAST
SIGNIFICANT) 16
CURRENT R&D PRIORITIES 16
TABLE 4 R&D FOCUSES FOR PRINCIPAL REGENERATIVE MEDICINE 17
TABLE 5 20-YEAR PLANNING HORIZON FOR REGENERATIVE MEDICINE BUSINESS:
LIKELY DEVELOPMENTS 18
NATIONAL SCIENCE FOUNDATION PRIORITIES 18
TABLE 6 NATIONAL SCIENCE FOUNDATION REGENERATIVE MEDICINE FUNDING
PRIORITIES AS OF MAY 1, 2013 ($) 19
TOTAL OUTPUT OF THE SECTOR 19
REGENERATIVE MEDICINE AND HEALTHCARE ECONOMICS 20
POPULATION TRENDS 21
MARKET TIMING 21
OVERSEAS INITIATIVES 21

CHAPTER 4 PRINCIPLE APPROACHES TO REGENERATIVE MEDICINE 24

HUMAN SUBSTANCES 25
CELLS AND TISSUES 25
TISSUE ENGINEERING 25
Importance of Scaffolding in Tissue Engineering 25
Plastic Scaffolding 26
Blood Vessel Scaffolding 27
Center for Integration of Medicine and Innovative Technology (CIMIT) 27
TABLE 7 PRINCIPLE R
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