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Regenerative Medicines: Bone and Joint Applications
Date:9/19/2013

TE INC. 299
WAKE FOREST INSTITUTE FOR REGENERATIVE MEDICINE 300
WRIGHT MEDICAL GROUP INC. 301
ZIMMER HOLDINGS INC. 301
OTHER ORGANIZATIONS INVOLVED IN REGENERATIVE MEDICINE R&D 302
ACADEMIC INSTITUTIONS 302
U.S. GOVERNMENT 303
OTHER SOCIETIES AND ORGANIZATIONS 303

CHAPTER 21 GLOSSARY OF KEY TERMS IN REGENERATIVE MEDICINE BUSINESS 306

LIST OF TABLES

SUMMARY TABLE U.S. MARKET FOR REGENERATIVE MEDICINE PRODUCTS USED IN
BONE AND JOINT APPLICATIONS, THROUGH 2018 ($ MILLIONS) 8
TABLE 1 FUNCTIONAL ACTIVITIES WITH REGENERATIVE MEDICINE SECTOR 11
TABLE 2 2012 REVENUES FOR TOP SUPPLIERS OF ORTHOPEDIC PRODUCTS AND
MATERIALS ($ BILLIONS) 12
TABLE 3 TEN PRINCIPAL MARKET DRIVERS (RANKED, MOST SIGNIFICANT TO LEAST
SIGNIFICANT) 16
TABLE 4 R&D FOCUSES FOR PRINCIPAL REGENERATIVE MEDICINE 17
TABLE 5 20-YEAR PLANNING HORIZON FOR REGENERATIVE MEDICINE BUSINESS:
LIKELY DEVELOPMENTS 18
TABLE 6 NATIONAL SCIENCE FOUNDATION REGENERATIVE MEDICINE FUNDING
PRIORITIES AS OF MAY 1, 2013 ($) 19
TABLE 7 PRINCIPLE RESEARCH PROJECTS OF CIMIT IN THE TISSUE-ENGINEERING
AND BIOMATERIALS FIELDS, 2008-2011 27
TABLE 8 COMPANIES INVOLVED IN BONE AND JOINT STEM CELL-BASED
THERAPEUTICS 33
TABLE 9 COMMERCIAL SUPPLIERS OF BIOREACTORS FOR USE IN REGENERATIVE
MEDICINE 36
TABLE 10 BONE MORPHOGENETIC PROTEINS 44
TABLE 11 TOTAL U.S. MARKET FOR TISSUE-ENGINEERED CARTILAGE PRODUCTS,
THROUGH 2018 ($ MILLIONS) 50
TABLE 12 FEDERAL FUNDING FOR STEM CELL RESEARCH THROUGH 2012 ($
MILLIONS) 59
TABLE 13 STATE LEVEL PROGRAMS FOCUSED ON STEM CELL RESEARCH 60
TABLE 14 CHARACTERISTICS OF IDEAL BONE GRAFT MATERIAL 76
TABLE 15 U.S. BONE GRAFT PROCEDURE VOLUMES BY APPLICATION, THROUGH
2018 77
TABLE 16 U.S. BONE GRAFT PROCEDURE VOLUMES BY TYPE OF GRAFT, THROUGH

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