Navigation Links
Refusing immunizations puts children at increased risk of pertussis infection
Date:5/25/2009

May 26, 2009 (DENVER) Children of parents who refuse vaccines are 23 times more likely to get whooping cough compared to fully immunized children, according to a new study led by a vaccine research team at Kaiser Permanente Colorado's Institute for Health Research.

The study will appear in the June 2009 issue of the journal Pediatrics, the journal of the American Academy of Pediatrics.

Funded by the National Institute of Allergy and Infectious Diseases, this is the first study to use electronic health records to look for immunization refusal and possible pertussis infections, making it the most definitive on the risk of vaccine refusal to date.

While most families vaccinate their children, leading to dramatic reductions in several serious childhood illnesses, the number of parents refusing immunizations appears to be increasing in the United States, researchers say. The study could not determine from the information available why parents elected to refuse vaccines. The study also did not evaluate the side effects of vaccines.

The study findings are important for parents who cite low risk of infection as a reason to choose fewer or no immunizations, and for researchers who are concerned that decreased immunization rates could lead to more disease outbreaks across the country.

"This study helps dispel one of the commonly held beliefs among vaccine-refusing parents: that their children are not at risk for vaccine preventable diseases," said study lead author Jason Glanz, Ph.D., a senior scientist at Kaiser Permanente's Institute for Health Research. "It also shows that the decision to refuse immunizations could have important ramifications for the health of the entire community. Based on our analysis, we found that one in 10 additional whooping cough infections could have been prevented by immunization."

Pertussis more commonly known as whooping cough is a highly contagious bacterial disease that causes uncontrollable, violent coughing and can be deadly in infants, especially those under two months of age who are too young to be fully vaccinated. In 1976 there were just over 1,000 reported cases of pertussis in the United States; by 2004, it climbed to nearly 26,000 cases. Between 2000 and 2005 there were 140 deaths resulting from pertussis in the United States.

The best way to prevent pertussis is through vaccinations. The childhood vaccine, DTaP, is a "3-in-1" immunization that protects against diphtheria, pertussis, and tetanus. It is given in a series to children at two months, four months, six months and 15-18 months of age, and a booster is given before kindergarten. The DTaP vaccine, like other routine childhood immunizations, has been shown to be more than 98 percent effective.

To assess the risk of DTaP refusal, researchers reviewed the electronic health records of children between the ages of two months and 18 years who were members of Kaiser Permanente Colorado between 1996 and 2007. First, investigators confirmed which children had pertussis infections. Next, they verified whether parents had refused some or all vaccines for their children.

The researchers found 156 laboratory-confirmed pertussis cases that met the study's criteria. They compared these cases to four times as many children of the same age and gender who were not infected with pertussis. Based on this analysis, the researchers discovered that children of vaccine refusers were 23 times more likely to be infected with whooping cough than vaccinated children.

"As a father of young children, I understand that vaccines can pose confusing and difficult choices, so the purpose of this research is to give parents more information to weigh the benefits and risks, and to provide pediatricians with more information to help participate in the discussion," Glanz said.

According to pediatrician and co-author Matthew F. Daley, MD, of The Children's Hospital Denver and Kaiser Permanente's Institute for Health Research: "Parents want to do what is best for their children and need information to make good decisions regarding immunizations. This study will benefit parents and pediatric health care providers because it helps us better understand some of the risks of not vaccinating against childhood diseases."


'/>"/>

Contact: Danielle Cass
danielle.x.cass@kp.org
510-267-5354
Kaiser Permanente
Source:Eurekalert

Related medicine news :

1. Refusing Immunizations Puts Children at Increased Risk of Pertussis Infection, Kaiser Permanente Study Finds
2. Parents of Autistic Children Fight Back -- Warn HMO Regulator Against Siding With Insurers Refusing to Pay for Treatment
3. Parents of Autistic Children Fight Back - Warn HMO Regulator Against Siding with Insurers Refusing to Pay for Treatment
4. San Francisco Health Plan is U.S. Leader in Childhood Immunizations
5. Independent Audit of Global Child Immunizations Urged
6. WXYZ-TV/Channel 7 is On Your Side With Healthy Living For Kids; Free Immunizations for Children on Sunday, August 24 at Charles H. Wright Museum of African American History
7. Immunizations Part of Back to School Preparations
8. STARscanner, STARband Cranial Helmets Making a Difference in the Lives of New York Children
9. STARscanner, STARband Cranial Helmets Making a Difference in the Lives of New Jersey Children
10. STARscanner, STARband Cranial Helmets Making a Difference in the Lives of Children
11. First of its kind study identifies risk factors for LRTIs in Inuit children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... February 08, 2016 , ... If you are feeling that ... you are not alone. According to the Center for Disease Control and Prevention (CDC), ... 2 diabetes and certain types of cancer, some of the leading causes of preventable ...
(Date:2/8/2016)... Francisco, CA (PRWEB) , ... February 08, 2016 , ... ... raise $792,000 to help combat pancreatic cancer. , Gary D. Radine, who recently retired ... also was the American Cancer Society’s 2015 CEO of the Year , helped ...
(Date:2/8/2016)... ... , ... Discover the Rocky Mountain region’s longest running and impressive garden and ... also get to see the most incredible gardens and home improvement experts that attend ... Colorado Convention Center - 700 14th St. Denver CO, is an exciting event that ...
(Date:2/8/2016)... ... February 08, 2016 , ... Guruji Mahendra Kumar Trivedi is ... 11th, 2016 in honor of his birthday on February 10th. During this time, ... Trivedi is known by over 250,000 people from over 40 different countries as an ...
(Date:2/7/2016)... ... February 07, 2016 , ... HealthSmart Holdings, Inc. announced today ... the tools and information to lower the costs, and increase the impact of ... providing employee healthcare benefits by as much as 22%:, + Price and ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... Feb.8, 2016 Alzheimer Diagnostic Tests - ... Medical Devices sector report , "Alzheimer Diagnostic ... an overview of Alzheimer Diagnostic Tests currently in ... on the pipeline products with comparative analysis of ... report reviews major players involved in the pipeline ...
(Date:2/8/2016)... 2016 Cardiovascular Surgery Devices - Medical ... Medical Devices sector report, "Cardiovascular Surgery Devices - ... of Cardiovascular Surgery Devices currently in pipeline stage. ... The report provides comprehensive information on the pipeline ... various stages of development. The report reviews major ...
(Date:2/8/2016)... NEW YORK , Feb. 8, 2016 /PRNewswire/ ... market, today announces its first male sexual enhancement ... enhancement, EnduramenT combines proven ethnobotanicals with a patented ... of nitric oxide, the chemical compound responsible for ... Forgoing the ...
Breaking Medicine Technology: