Navigation Links
Red wine's resveratrol may help battle obesity

Resveratrol, a compound present in grapes and red wine, reduces the number of fat cells and may one day be used to treat or prevent obesity, according to a new study. The results will be presented at The Endocrine Society's 90th Annual Meeting in San Francisco.

Past research found that resveratrol protected laboratory mice that were fed a high-calorie diet from the health problems of obesity, by mimicking the effects of calorie restriction. Researchers at the University of Ulm in Germany wanted to know if resveratrol could mimic the effects of calorie restriction in human fat cells by changing their size or function. The German team used a strain of human fat cell precursors, called preadipocytes. In the body, these cells develop into mature fat cells, according to the study's lead author, Pamela Fischer-Posovszky, PhD, a pediatric endocrinology research fellow in the university's Diabetes and Obesity Unit.

In the cell-based study, they found that resveratrol inhibited the pre-fat cells from increasing and prevented them from converting into mature fat cells. Also, resveratrol hindered fat storage. Most interesting, according to Fischer-Posovszky, was that resveratrol reduced production of certain cytokines (interleukins 6 and 8), substances that may be linked to the development of obesity-related disorders, such as diabetes and clogged coronary arteries. Also, resveratrol stimulated formation of a protein known to decrease the risk of heart attack. Obesity decreases this substance, called adiponectin.

The new finding is consistent with the theory that the resveratrol in red wine explains the French paradox, the observation that French people eat a relatively high-fat diet but have a low death rate from heart disease.

"Resveratrol has anti-obesity properties by exerting its effects directly on the fat cells," Fischer-Posovszky said. "Thus, resveratrol might help to prevent development of obesity or might be suited to treating obesity."

Fischer-Posovszky cautioned that, while the health benefits of resveratrol seem promising, there is not sufficient knowledge about the effects of long-term treatment. One small study found that a single dose of up to 5 grams of resveratrol (much higher than the amount in a bottle of red wine) caused no serious ill effects in healthy volunteers, she pointed out. However, she said another study theorized that resveratrol may stimulate the growth of human breast cancer cells, possibly because resveratrol's chemical structure is similar to a phytoestrogen, an estrogen-like substance found in some plants.


Contact: Aaron Lohr
The Endocrine Society

Related medicine news :

1. Photos: Drink Wine and Live Longer - 1907 Madiran and Plaimont Wines of Southwest France Sponsor the Launch of The Red Wine Diet
2. Consumers Being Misled Over Bioavailabity of Resveratrol
3. Dr. William S. Gruss, M.D., Says That Medical Research Shows You Can Reduce Your Risk of Cancer By Up To 77% and Reverse the Effects of Aging in A CARDIOLOGISTS GUIDE TO ... ANTI-AGING, ANTIOXIDANTS & RESVERATROL
4. New: Longevinex(R) First to Introduce Micronized Resveratrol Matrix - Now Stabilized by Microencapsulation
5. Resveratrol: Thousands of Bottles of Wine, High-Dose Pills Not Required; Mega-doses May Induce Side Effects
6. Battle Continues Over Vietnam PTSD Numbers
7. Life-Saving News for Battlefield Soldiers & Wounded Civilians
8. The Fight for His Life: Author, Family Battle Disease and Challenge Politics in the Face of Survival
9. National Battle of the Hospital Chefs Cooks Up a Winner
10. Parents can Help Young Superheroes Battle Cavities on Halloween Night
11. Early predictive model may be new weapon against leading cause of death on battlefield
Post Your Comments:
(Date:11/24/2015)... FL (PRWEB) , ... November 24, 2015 , ... In ... a growing epidemic as deaths from prescription opioids in the United States grew 400 ... cocaine. In 2013 alone, opioids were involved in 37 percent of all fatal drug ...
(Date:11/24/2015)... ... , ... Serenity Point Rehabilitation, a holistic treatment center for substance abuse located ... the staff members at their recovery center. The videos highlight some of the various ... the things that make their recovery program so unique. , “Making the decision to ...
(Date:11/24/2015)... ... November 24, 2015 , ... Chiropractic student Katie Benson received ... in Overland Park, Kansas. Benson, a fifth-trimester student in the university’s College of ... on October 16. , “Katie is very excited and greatly appreciative to receive ...
(Date:11/24/2015)... ... November 24, 2015 , ... Autism Speaks, the world’s leading autism science ... social media and the generosity of people around the world. On December 1, supporters ... to give – and share the personal stories behind those gifts. , Just ...
(Date:11/24/2015)... IL (PRWEB) , ... November 24, 2015 , ... ... and engineer of patented products, announces Fragrance by Marcelle, a cosmetic invention which ... The Perfume & Fragrance Manufacturing Market in the US is worth $3 billion ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... 24, 2015  Freudenberg Medical has developed specialty tubing for ... of medical facilities. Africa and ... is sparse. Nevertheless, prompt diagnosis is important to treat those ... virus. With the help of a portable mini-lab or "lab ... village in affected areas and perform rapid testing for HIV. ...
(Date:11/24/2015)... November 24, 2015 Edelris announce today ... co-own with Inserm, Poxel, CNRS, UCBL and ENS-Lyon on a ... --> Hepatitis B virus (HBV) infection is ... people chronically infected worldwide, 20 to 40% of them being ... carcinoma. Despite the existence of an effective preventive vaccine, the ...
(Date:11/24/2015)... Ill. , Nov. 24, 2015  Wellness Center USA ... November shipments of its flagship product, Psoria-Light® (PL 1000), to targeted dermatology ... Houston, Minnesota , and North Carolina ... Cleveland , Chicago , and ... --> Revenue for the earlier shipments reported on October ...
Breaking Medicine Technology: