Navigation Links
Recurrence of Oral Cancer Found to Signal Poor Outcome
Date:12/22/2010

WEDNESDAY, Dec. 22 (HealthDay News) -- How people fare when oral cancer recurs depends on where and when the cancer returns, a new study has found.

The research included 77 people in Australia who'd had oral squamous cell carcinoma, a cancer that occurs in the thin, flat cells that line the lips and mouth. The cancer was treated with surgery, radiation or both. However, the cancer came back, and they all subsequently had what's called salvage surgery, which is a procedure to remove cancer after an initial treatment fails.

The researchers found that people whose cancer recurred at the same site as the initial cancer tended to do worse if the disease returned within six months, whereas those with recurrence at a different site did worse if their cancer came back after six months or more.

The overall five-year survival rate after salvage surgery was 50 percent. People who had initially had both surgery and radiation were 1.3 times as likely to die, the investigators found.

The median, or midpoint, in time to recurrence was 7.5 months after treatment, and 86 percent of the recurrences occurred within 24 months, the study found. Recurrence occurred at the initial site in 39 people, in the neck on the same side as their initial cancer in 27 people and in the neck on the opposite side in 11 people.

"Presumably, the poor outcome reflects a combination of more advanced disease at initial presentation, resistant tumor biology and limited salvage options," wrote Michael D. Kernohan and his colleagues from the Royal Prince Alfred Hospital in Camperdown, Australia. "These findings suggest that patients whose disease fails maximal combination therapy have a low likelihood of successful salvage; we recommend that such patients be counseled accordingly."

The study is published in the December issue of Archives of Otolaryngology -- Head & Neck Surgery.

More information

The U.S. National Cancer Institute has more about oral cancer.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Dec. 20, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
2. After a Stroke, High Risk for a Recurrence
3. Delaying post-surgical radiation increases risk of breast cancer recurrence in older women
4. Costly tests may not help detect bladder cancer recurrence, M. D. Anderson study finds
5. Recurrence of breast cancer after more than 10 years is an important indicator of survival
6. Obesity and weight gain near time of prostate cancer surgery doubles risk of recurrence
7. FDG-PET/CT plays a definite role in detecting colorectal cancer recurrences
8. Patients at high risk of recurrences of heart disease: Breakthrough in prevention
9. Pain Med May Affect Breast Cancer Recurrence
10. Dont Count on Selenium to Prevent Lung Cancer Recurrence
11. Intervention program helps breast cancer patients live longer after recurrence
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Recurrence of Oral Cancer Found to Signal Poor Outcome
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their media with ... X," said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color ... users can now reveal the media of their split screens with growing colorful ...
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... TopConsumerReviews.com recently ... of Eyeglasses . , Millions of individuals in the United States and Canada ... become a way to both correct vision and make a fashion statement. Even celebrities ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet ... product that was developed to enhance the health of felines. The formula is all-natural ... two main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Austin residents seeking ... American College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical ... effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by ...
(Date:6/25/2016)... , ... June 25, 2016 , ... As a lifelong ... Cum Laude and his M.D from the David Geffen School of Medicine at UCLA. ... to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... HILL, N.C. , June 24, 2016 /PRNewswire/ ... healthcare decisions and regulators/payers have placed more emphasis ... new environment, patient support programs in the pharmaceutical ... for patients, medications. Consequently, pharmaceutical companies are focusing ... ensure they are providing products and services that ...
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... , June 24, 2016 According ... by Type (Standard Pen Needles, Safety Pen Needles), Needle ... GLP-1, Growth Hormone), Mode of Purchase (Retail, Non-Retail) - ... This report studies the market for the forecast period ... reach USD 2.81 Billion by 2021 from USD 1.65 ...
Breaking Medicine Technology: