Navigation Links
Recurrence of Oral Cancer Found to Signal Poor Outcome
Date:12/22/2010

WEDNESDAY, Dec. 22 (HealthDay News) -- How people fare when oral cancer recurs depends on where and when the cancer returns, a new study has found.

The research included 77 people in Australia who'd had oral squamous cell carcinoma, a cancer that occurs in the thin, flat cells that line the lips and mouth. The cancer was treated with surgery, radiation or both. However, the cancer came back, and they all subsequently had what's called salvage surgery, which is a procedure to remove cancer after an initial treatment fails.

The researchers found that people whose cancer recurred at the same site as the initial cancer tended to do worse if the disease returned within six months, whereas those with recurrence at a different site did worse if their cancer came back after six months or more.

The overall five-year survival rate after salvage surgery was 50 percent. People who had initially had both surgery and radiation were 1.3 times as likely to die, the investigators found.

The median, or midpoint, in time to recurrence was 7.5 months after treatment, and 86 percent of the recurrences occurred within 24 months, the study found. Recurrence occurred at the initial site in 39 people, in the neck on the same side as their initial cancer in 27 people and in the neck on the opposite side in 11 people.

"Presumably, the poor outcome reflects a combination of more advanced disease at initial presentation, resistant tumor biology and limited salvage options," wrote Michael D. Kernohan and his colleagues from the Royal Prince Alfred Hospital in Camperdown, Australia. "These findings suggest that patients whose disease fails maximal combination therapy have a low likelihood of successful salvage; we recommend that such patients be counseled accordingly."

The study is published in the December issue of Archives of Otolaryngology -- Head & Neck Surgery.

More information

The U.S. National Cancer Institute has more about oral cancer.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Dec. 20, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
2. After a Stroke, High Risk for a Recurrence
3. Delaying post-surgical radiation increases risk of breast cancer recurrence in older women
4. Costly tests may not help detect bladder cancer recurrence, M. D. Anderson study finds
5. Recurrence of breast cancer after more than 10 years is an important indicator of survival
6. Obesity and weight gain near time of prostate cancer surgery doubles risk of recurrence
7. FDG-PET/CT plays a definite role in detecting colorectal cancer recurrences
8. Patients at high risk of recurrences of heart disease: Breakthrough in prevention
9. Pain Med May Affect Breast Cancer Recurrence
10. Dont Count on Selenium to Prevent Lung Cancer Recurrence
11. Intervention program helps breast cancer patients live longer after recurrence
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Recurrence of Oral Cancer Found to Signal Poor Outcome
(Date:2/28/2017)... City, Utah (PRWEB) , ... February 28, 2017 , ... ... is a time for everyone to reaffirm their commitment to improving cardiovascular health for ... of death for men and women. Every year, one in four deaths are caused ...
(Date:2/27/2017)... WI (PRWEB) , ... February 27, 2017 , ... Bo ... Investigator Award. Dr. Chen will receive his award during the Plenary Session at ASLMS ... (ASLMS), to be held in San Diego, California April 5-9, 2017. , During ...
(Date:2/27/2017)... ... 27, 2017 , ... Much attention has been paid to the problem of ... opioid painkillers has fallen short. From 1999 until 2010, fatal overdoses from prescription pain ... overdoses in male populations.(1) , The proportion of women using illicit drugs is also ...
(Date:2/27/2017)... Shenzhen, China (PRWEB) , ... February 26, 2017 , ... ... , This pioneer sound and video system brings songs, movies, TV shows and much ... 3D sound offers clear, high-definition sound. An immersive view of 1280 x 720 provides ...
(Date:2/27/2017)... , ... February 27, 2017 , ... ... Francisco and environs, is proud to announce an upgrade to the company's Yelp ... upgraded Yelp page on topics as diverse as Platelet Rich Plasma (PRP) therapy, ...
Breaking Medicine News(10 mins):
(Date:2/28/2017)... This report provides all the information you ... and activities since 2010. Download the full ... Deals and Alliance since 2010 report provides an in-depth ... world,s leading life sciences companies. On demand ... of the most up to date deal and company ...
(Date:2/28/2017)... 2017   Fourth-quarter 2016 ... $4,010 million to top end of guidance ... impairment charges in fourth-quarter 2016 associated with the write-down ... Company,s Generics reporting unit ... continuing operations; Full-year 2016 reported $14.48 diluted (GAAP) loss ...
(Date:2/27/2017)... Inc. (NYSE: HYH ) today reported fourth quarter ... related key planning assumptions. Executive Summary 2016 fourth ... compared to the prior year. Net income ... net income of $15 million in the fourth quarter of ... to adjusted net income of $27 million in the prior ...
Breaking Medicine Technology: