Navigation Links
Recruiting E. coli to combat hard-to-treat bacterial infections
Date:10/2/2013

The notorious bacteria E. coli is best known for making people sick, but scientists have reprogrammed the microbe which also comes in harmless varieties to make it seek out and fight other disease-causing pathogens. The researchers' report appears in the journal ACS Synthetic Biology and describes development of this new type of E. coli that can even kill off slimy groups of bacteria called biofilms that are responsible for many hard-to-treat infections, such as those that take hold in the lungs, the bladder and on implanted medical devices.

Matthew Wook Chang and colleagues explain that biofilm infections are difficult to treat because the bacteria hide away under a protective barrier of sugars, DNA and proteins. That shield makes them very resistant to conventional therapies. In addition, overuse of antibiotics in medicine and agriculture also have made some bacteria, such as MRSA, shrug off most known treatments, making at least 2 million Americans sick every year. This growing public health threat has motivated scientists to look for new antibiotics and alternative treatments to beat infections. In the past, researchers made bacteria that fight off other microbes, but they had limitations. Chang's team addressed those limitations by making a new kind of bacterial "gun-for-hire" that can sense an infection, swim toward it and kill off the disease-causing microbes.

They reprogrammed E. coli to sense Pseudomonas aeruginosa a bacteria that can form biofilms and causes hospital-acquired infections in the lungs and the gut. The new E. coli then swims directly toward P. aeruginosa and launches an attack with an antimicrobial peptide and an enzyme that breaks down biofilms. Though the researchers successfully tested their engineered microbe on P. aeruginosa, they say that their engineering strategy could be used to combat other pathogens as well.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Recruiting for Good Launches Pet Philanthropy Program to Collaboratively Fundraise for Kitt Crusaders an Animal Rescue Organization
2. Online Recruiting Service PlentyofJobs.com Announces Integration with eQuest and Offers a Complimentary Job Posting Promotion on Facebook
3. Human Capital Resource, LLC, Adds Contract Staffing to Its Recruiting Services
4. myCNAjobs Unveiling New Caregiver Recruiting Technology During Upcoming HomeCare Association Conference
5. UCLA researchers combat global disease with a cell phone, Google Maps and a lot of ingenuity
6. For Combat Vets, Brain Injury Symptoms Can Last Years
7. Local Woodinville Contractor, Washington State Kitchen and Bath, Combats Toxic Mold, Adhering to the Toughest Mold Protection Standards in the Nation with New Promotion
8. Undergrads invent cell phone screener to combat anemia in developing world
9. Couples Therapy May Help Combat PTSD
10. New technology combats global pandemic of drug counterfeiting
11. Simple new test to combat counterfeit drug problem in developing countries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... UT (PRWEB) August 20, 2014 ... Solution, announced the publication of a new eBook, ... Benefits, many small business owners feel uncertain about ... their family, and their bottom line. , The ... FAQs, and helps businesses navigate their upcoming health ...
(Date:8/20/2014)... A new trend in the insurance ... before issuing an approximate quote for insurance coverage, according ... helping the public to obtain life insurance quotes without ... http://quotespros.com/life-insurance.html . , The coverage industry has changed ... appeared in many U.S. states. Some consumers are now ...
(Date:8/20/2014)... August 20, 2014 Locating rates for insurance ... the Quotes Pros website. A new source of term life ... review rates good for all 50 states at http://quotespros.com/life-insurance.html ... one of the new methods available for the public to ... that are supplied. The instant quotations that are available are ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 Ticket Down ... tickets in NYC. In just a week, the U.S. ... King Tennis Center. The event was originally founded in 1881 and ... Rafael Nadal was forced to withdrawal from the event because of ... women’s tournament and will return to New York City with hopes ...
(Date:8/20/2014)... Aug. 19, 2014 (HealthDay News) -- A group representing ... get a flu shot. According to the American ... in recent years have upheld the safety and effectiveness ... is highly infectious and can be particularly dangerous to ... and other complications," Dr. Laura Riley, chair of the ...
Breaking Medicine News(10 mins):Health News:Life Insurance Quotes Without Medical Exams Now Displayed to Adults at Insurance Website 2Health News:Term Life Insurance Price Database Now Helps Quote Prices for Adults in 50 States Online 2Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 2Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 3Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 4Health News:2014 U.S. Open Tennis Tickets: Ticket Down Slashes Ticket Prices on All US Open Tennis Championship Sessions in New York at Arthur Ashe Stadium 5Health News:All Pregnant Women Need Flu Shot: Ob/Gyn Group 2
... vaccination and a lack of time as main reasons adults avoid ... ... December 10, 2008 -- A new survey of approximately 4,000 American ... against the flu this season. The survey is the first of ...
... Dec. 10 Markel Corporation is,pleased to announce the ... insurance product. DataBreach(SM) helps businesses manage,risk associated with their ... information in their custody or care. , ... to the increase in identity theft,that has been plaguing ...
... might yield new insights into eating disorders, experts say ... verifying what many overeaters have suspected for a long ... sweetener seems to prompt the same chemical changes in ... as cocaine and heroin. , The findings were to ...
... Healthcare Management Systems,Inc.(R) (HMS) hospital customers completed three paintings ... were entered into a drawing,to receive the paintings to ... Recipients of the 4-foot by 6-foot, multiple-canvas paintings were,announced ... HMS, annual,conference. , , ...
... to Attempt to Prevent Complete Vision Loss in Patient ... Dec. 10 NeoVista, Inc., announced today that ... the company,s "compassionate case" waiver to utilize its novel ... with an advanced form of the disease who did ...
... children, new government survey says , , WEDNESDAY, Dec. ... U.S. adults and 12 percent of children use some ... government survey finds. , Complementary and alternative medicine -- ... a collection of wide-ranging medical and health care systems, ...
Cached Medicine News:Health News:Mid-Season Flu Immunization Rates are Too Low 2Health News:Mid-Season Flu Immunization Rates are Too Low 3Health News:Mid-Season Flu Immunization Rates are Too Low 4Health News:Mid-Season Flu Immunization Rates are Too Low 5Health News:Markel Corporation Announces New DataBreach(SM) Privacy Liability Coverage 2Health News:Study Suggests Sugar May Be Addictive 2Health News:Study Suggests Sugar May Be Addictive 3Health News:HMS Donates Hospital Art 2Health News:FDA Grants NeoVista's Request to Utilize Novel Wet AMD Treatment in Compassionate Case 2Health News:FDA Grants NeoVista's Request to Utilize Novel Wet AMD Treatment in Compassionate Case 3Health News:38% of U.S. Adults Use Alternative Treatments 2Health News:38% of U.S. Adults Use Alternative Treatments 3
(Date:8/20/2014)... LUTHERVILLE, Md. , Aug. 20, 2014 /PRNewswire/ ... today lauded the latest results achieved by the ... known as the National Precursor Log Exchange (NPLEx), ... enforcement officials track down meth offenders and make ... in Indiana blocked the ...
(Date:8/20/2014)... Md. , Aug. 20, 2014  The ... lauded the latest results achieved by the real-time, ... as the National Precursor Log Exchange (NPLEx), automatically ... officials track down meth offenders and make arrests. ... Kentucky blocked the sale ...
(Date:8/20/2014)... 20, 2014 The National Association of ... results achieved by the real-time, pseudoephedrine (PSE) blocking ... Precursor Log Exchange (NPLEx), automatically blocks unlawful pseudoephedrine ... meth offenders and make arrests. Data released by ... blocked the sale of more than ...
Breaking Medicine Technology:Indiana's Stop-Sale System Achieves Significant Results In Battle Against Meth 2Kentucky's Stop-Sale System Achieves Significant Results In Battle Against Meth 2Kansas's Stop-Sale System Achieves Significant Results In Battle Against Meth 2
... Therapeutics,(Amex: CXM ) and its operating ... from a preclinical study, demonstrating a new ... for the potential,treatment of acute myocardial infarction ... Central (BMC) Cardiovascular Disorders (2008, 8:7, April,10, ...
... Regimen Designed to Avoid Risk of Toxicity ... Associated with Nucleoside Class of HIV Drugs, ... ) today announced that it has initiated a Phase ... in first-line therapy of adult treatment-naive HIV-infected patients,with R5-type ...
Cached Medicine Technology:Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 2Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 3Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 4Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 5Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 6Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 7Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 8Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 9Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 10Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 11Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack 12Schering-Plough Initiates Phase II Study With Vicriviroc in Treatment-Naive HIV-Infected Patients 2Schering-Plough Initiates Phase II Study With Vicriviroc in Treatment-Naive HIV-Infected Patients 3Schering-Plough Initiates Phase II Study With Vicriviroc in Treatment-Naive HIV-Infected Patients 4Schering-Plough Initiates Phase II Study With Vicriviroc in Treatment-Naive HIV-Infected Patients 5Schering-Plough Initiates Phase II Study With Vicriviroc in Treatment-Naive HIV-Infected Patients 6
... The series SV stereomicroscopes are ... Thanks to their mature modular ... the job in hand. This ... of demanding routine applications will ...
10:1 Zoom Ratio - The parallel optical system of the SMZ-1000 has a 10:1 zoom with clickstops at 1X intervals. It features a zoom range of 0.8X to 8.0X and total magnification (depending on eyepieces...
... ratio of 15:1, a zoom ... and the convenience of clickstops ... to 11X, observation becomes easier ... to 540X can be obtained ...
Inquire...
Medicine Products: