Navigation Links
Reconstructing mandibular defects with bioengineered tooth and bone
Date:4/5/2008

Current strategies for jaw reconstruction require multiple procedures, first to repair the bone defect to offer sufficient support, and then to place the tooth implant. The entire procedure can be painful and time-consuming, and the desired esthetic and functional repair can be achieved only when both steps are successful. Although the patients quality of life can be improved significantly, the prognosis is often unpredictable, especially in young patients, whose jaws continue to grow, while the implant remains fixed. The ability to bioengineer combined tooth and bone constructs, which would grow in a coordinated fashion with the surrounding tissues, could potentially improve the clinical outcomes, and also reduce patient suffering.

Under the guidance of Dr. Pamela C. Yelick, a research team at Tufts University (Boston, MA) has examined the feasibility of simultaneously reconstructing both teeth and bone. In 2002, the group first reported the regeneration of tooth crowns, from cultured tooth bud cells seeded onto biodegradable scaffolds and implanted into rat hosts. The morphology of the developing tissue-engineered tooth crowns closely resembled that of naturally formed teeth. Next, they generated a hybrid tooth-bone construct, by combining a bone-marrow-derived stem-cell-seeded scaffold with the previously used tooth model, implanted and grown in the omenta (tissues connecting abdominal structures) of rat hosts. In this case, the formation of not only the tooth crowns but also tooth root and surrounding alveolar bone was observed. However, since the omentum offers an environment quite distinct from that of the natural tooth site, the jawbone, the team examined hybrid tooth-bone construct development using third molar tooth bud cells and bone marrow derived from, and implanted back into, the same minipig.

Their results showed the formation of organized bioengineered dental tissues closely resembling those of naturally formed teeth, includin
'/>"/>

Contact: Linda Hemphill
lhemphill@iadr.org
703-299-8091
International & American Association for Dental Research
Source:Eurekalert

1

GOOD

Page: 1 2

Related medicine news :

1. Folic Acid in the Food Supply Reduces Birth Defects, but May Cause Extra Cancers, Reports the Harvard Womens Health Watch
2. Congenital heart defects increasing among IVF twins
3. Babies With Heart Defects Do Best at Hospitals With Most Experience
4. For babies with heart defects, death risk is far lower at most experienced hospitals
5. Procedure to detect fetal heart defects is first automated use of 3-D ultrasound
6. Hazardous Advanced Micro Devices (A.M.D.) Clean Room Chemicals Caused Multiple Birth Defects, Lawsuit Alleges
7. Heart Defects Can Delay Babys Brain Development
8. Cell-surface sugar defects may trigger nerve damage in multiple sclerosis patients
9. Another Reason Not to Smoke While Pregnant: Birth Defects
10. Toms of Maine Introduces a Patent-Pending New Formula with the Launch of its Natural Clean & Gentle Care and Sensitive Care Toothpastes
11. The Disappearing Toothbrush: Survey Reveals Kids Top Excuses to Avoid Brushing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... Studies from Johns Hopkins University reveal a ... and their inability to get adequate sleep. These same ... naturally relieve many symptoms. , Johns Hopkins University ... was significantly associated with overall weight loss, especially belly ... November 6th, 2012, researchers monitored 77 participants who were ...
(Date:5/25/2013)... May 25, 2013 On May 20, 2013 ... do not wish to discuss or plan for their eventual ... FuneralFinancials.com released a Must-Do List to help people ... Financials recommends, “Creating a personal fact sheet.” , While not ... financial information and personal data. It may include a ...
(Date:5/25/2013)... May 25, 2013 By working diligently ... declared the integration of the 2012 Lamborghini Aventador into ... the latest entrant in the list of vehicles lined ... vehicle is all set to thrill automobile lovers in ... power and spectacular looks, the 2012 Lamborghini Aventador comes ...
(Date:5/25/2013)... orthodontists have thought about moving their office to the ... Most people would naturally assume that the company they'd ... and support would own and maintain all the physical ... wrong. Cloud providers lease space in a ... servers and related equipment to run cloud environments) owned ...
(Date:5/25/2013)... Acuity Games ’ innovative brain games ... Word Hunt is available today, expanding it beyond ... Flash 2, Sudoku and Matchematics will roll out over the ... revolutionary lifetime brain fitness measurement have been re-optimized for the ... of brain fitness measurement in your pocket. What could ...
Breaking Medicine News(10 mins):Health News:hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offers Newly Improved hCG Diet Plans Capable of Delivering Better Sleep 2Health News:FuneralFinancials.com Releases Last Wishes Must-Do List 2Health News:Rim Fitments Provider SizeItUp Launches The Database Integration For The 2012 Lamborghini Aventador 2Health News:Cirrus Ortho Launches Cloud Computing for Orthodontic Industry That is Unlike Any Other 2Health News:Acuity Games Apps Come to the iPhone 2
... Mich., April 1, 2008 ,The Institute for Health ... Health Workplace Center for employers with,founding sponsor HealthMedia, ... demonstrable outcomes. Employers are now paying,attention to this ... -- Behavioral health conditions account for nearly 8% ...
... Researchers Studying New Way to Rehabilitate Stroke Patients, ... people who experience a stroke each year, many never ... their stroke. But physical,therapists, using a specialized treadmill, have ... -- correctly., The results of their study, conducted ...
... ... Named, FRANKLIN LAKES, N.J., April 1, 2008 At the annual,National ... Anthony Welters, Dr. June E. Osborn and Dr. Nelson L. Adams,were the ... Award, respectively., The event was held at the Union League Club ...
... Global,marketing information firm J.D. Power and Associates, ... 40th anniversary today, marking,four decades of fulfilling the ... integrating the voice of the customer into business ... http://www.newscom.com/cgi-bin/prnh/20050527/LAF028LOGO-a ), In 1968, Power established ...
... 1, 2008 Rap music has gone from an art ... to one that often glorifies illegal drug use, according to ... nearly two decades. The study is published in the ... reviewed scientific journal., Positive portrayals of drug use have increased ...
... good patient care , , MONDAY, March 31 (HealthDay News) ... concept of national health insurance, which represents a shift ... survey finds. , Typically, national health insurance plans ... guarantees health coverage for everyone. In most cases, these ...
Cached Medicine News:Health News:IHPM and HealthMedia Announce Industry's First Behavioral Health Workplace Center for Employers 2Health News:IHPM and HealthMedia Announce Industry's First Behavioral Health Workplace Center for Employers 3Health News:Stroke Patients Re-Learn to Walk Correctly Again Using Special Treadmill 2Health News:The Changing Face of Medicine: National Medical Fellowships Annual Awards Gala Honors Three Fellows 2Health News:The Changing Face of Medicine: National Medical Fellowships Annual Awards Gala Honors Three Fellows 3Health News:J.D. Power and Associates Celebrates 40th Anniversary of Representing the Voice of the Customer 2Health News:J.D. Power and Associates Celebrates 40th Anniversary of Representing the Voice of the Customer 3Health News:J.D. Power and Associates Celebrates 40th Anniversary of Representing the Voice of the Customer 4Health News:J.D. Power and Associates Celebrates 40th Anniversary of Representing the Voice of the Customer 5Health News:Drug use increasingly glamorized in rap music, according to new study of 2-decade trends 2Health News:Drug use increasingly glamorized in rap music, according to new study of 2-decade trends 3Health News:Majority of U.S. Doctors Back National Insurance Plan 2
(Date:5/23/2013)... 23, 2013  Texas, premier physician associations today announced ... survival tools they need to provide demonstrably better and ... care marketplace. "I am confident the Physician ... said Stephen L. Brotherton , MD, ... Texas doctors are determined to make health ...
(Date:5/23/2013)... -- Ameritox, the nation,s leader in pain medication monitoring, ... become part of its Urine Drug Monitoring (UDM) ... improve the clinical outcomes for injured workers. ... in the workers, compensation industry, has used UDM ... strategy for several years. By establishing a comprehensive ...
(Date:5/23/2013)... -- CAS Medical Systems, Inc. (NASDAQ: CASM ) (CASMED), ... announced that Thomas M. Patton , President ... Annual Marcum MicroCap Conference on Thursday, May 30, 2013, ... City . The presentation is scheduled to ... and will be available via a live webcast at ...
Breaking Medicine Technology:TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 2Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 3CASMED to Present at the 2nd Annual Marcum MicroCap Conference 2
... Specialty Medicines Companies (ASMC), an informal working group of ... about H.R. 3962, the "Affordable Health Care for America ... smaller companies fear that the cumulative effect of a ... efforts to bring new medicines to market. ...
... Virtual Health Technologies, Inc. (OTC Bulletin Board: VHGI) confirmed ... all health care related assets to Wound Management Technologies, Inc ... of Directors and shareholders of VHGI. , ... dividend, royalty stream and cash realized from the transaction would ...
Cached Medicine Technology:Statement of America's Specialty Medicines Companies On House Health Care Bill (H.R. 3962) 2OTCBB-VHGI Updates Shareholders on Status of Healthcare Asset Sale and Treasure Gulch Gold Mine Development Strategy 2OTCBB-VHGI Updates Shareholders on Status of Healthcare Asset Sale and Treasure Gulch Gold Mine Development Strategy 3OTCBB-VHGI Updates Shareholders on Status of Healthcare Asset Sale and Treasure Gulch Gold Mine Development Strategy 4